ALTERNATIVE MOLECULARLY IMPRINTED POLYMERIC MEMBRANES FROM A TETRAPEPTIDE RESIDUE CONSISTING OF D-AMINO-ACIDS OR L-AMINO-ACIDS

Alternative molecularly imprinted polymeric membranes were prepared fr om a polystyrene resin bearing tetrapeptides consisting of D-amino aci ds or L-amino acids. The membrane prepared from a DLDE derivative (H-A sp(OcHex)-Leu-Asp(OcHex)-Glu(OBzl)-CH2-) consisting of D-amino acids a nd imprinted by Boc-D-Trp recognizes the D-isomer in preference to the corresponding L-isomer and vice versa. The amino acid preferentially adsorbed by the membrane was selectively permeated by applying electro dialysis.