M. Tori et al., SYNTHESIS OF LIVERWORT SESQUITERPENE (-)-ISOCUPARENE(HERBERTENE) VIA A DIELS-ALDER REACTION USING PHENYLETHYLAMINE AS CHIRAL AUXILIARY, Tetrahedron : asymmetry, 8(16), 1997, pp. 2731-2738
The imine of 2-methylcyclopentanone with (S)(-)-phenylethylamine was s
ubjected to reaction with methyl propiolate and the product was transf
ormed into (-)-isocuparene by use of a Diels-Alder reaction to constru
ct the aromatic ring. (C) 1997 Elsevier Science Ltd.