A STEREOSELECTIVE SYNTHESIS OF MALBRANICIN

Authors
VANDERLEI JML COELHO F ALMEIDA WP
Citation
Jml. Vanderlei et al., A STEREOSELECTIVE SYNTHESIS OF MALBRANICIN, Tetrahedron : asymmetry, 8(16), 1997, pp. 2781-2785
Citations number
16
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Inorganic & Nuclear","Chemistry Physical
Journal title
Tetrahedron : asymmetry → ACNP
ISSN journal
09574166
Volume
8
Issue
16
Year of publication
1997
Pages
2781 - 2785
Database
ISI
SICI code
0957-4166(1997)8:16<2781:ASSOM>2.0.ZU;2-L
Abstract
In this communication we describe the first synthesis of Malbranicin, a novel antibiotic quinone, isolated from Malbranchea cinnamomea. Our strategy was based on a diastereoselective alkylation of a chiral oxaz olidinone enolate. Our results suggest the absolute configuration of t his compound. (C) 1997 Elsevier Science Ltd.