SARCOIDOSIS INVOLVING THE THYROID AND PLEURA

We report the coincidence of uncommon manifestations of sarcoidosis, e ach confirmed by percutaneous needle biopsy, revealing noncaseating gr anulomas. A patient presented with a thyroid nodule which demonstrated noncaseating granulomas on biopsy. When pleural effusion subsequently developed, pleural biopsy demonstrated noncaseating granulomas with n o acid fast bacilli on stain or culture, and a diagnosis of sarcoidosi s was made, Thyroid and pleural involvement are each rare manifestatio ns of sarcoidosis, and are usually associated with extensive systemic disease. The diagnosis of sarcoidosis requires the appropriate clinica l presentation, compatible histologic findings, and evaluation for oth er causes of granuloma formation.