A. Zamecnikova et al., KARYOTYPIC AND CLINICAL PROGRESSION OF ANLL IN A PATIENT WITH CONSTITUTIONAL DER(15-21)(Q10-Q10), Cancer genetics and cytogenetics, 98(1), 1997, pp. 81-83
A patient with a constitutional chromosomal abnormality who developed
acute nonlymphocytic leukemia (ANLL-M4) at the age of 31 is presented.
At the time of diagnosis the only acquired chromosomal change was the
presence of a small marker chromosome. The patient was studied period
ically for 11 years during his illness with no evidence of karyotypic
progression, until the last study, when a deletion of the long arm of
chromosome 7 was detected. (C) Elsevier Science, Inc., 1997.