Fq. Ye et al., QUANTITATION OF REGIONAL CEREBRAL BLOOD-FLOW INCREASES DURING MOTOR ACTIVATION - A STEADY-STATE ARTERIAL SPIN TAGGING STUDY, NeuroImage, 6(2), 1997, pp. 104-112
Steady-state arterial. spin tagging MRI approaches were used to quanti
tate regional cerebral blood flow increases during finger tapping task
s in seven normal subjects. Statistically significant increases in cer
ebral blood flow were observed ill the contralateral primary sensorimo
tor cortex in all seven subjects and in the supplementary motor area i
n five subjects. The intrinsic spatial resolution of the cerebral bloo
d flow images was similar to 4 mna. If no spatial filtering was applie
d, the average increase in cerebral blood flow in the activated primar
y sensorimotor cortex was 60 +/- 10 cc/100 g/min (91 +/- 32%). If the
images were filtered to a spatial resolution of 15 mm, the average inc
rease in cerebral blood flow in the activated primary sensorimotor cor
tex was 23 +/- 7 cc/100 g/min (42 +/- 15%), in agreement with previous
ly reported Xe-133 slid PET results. (C) 1997 Academic Press.