This review describes the findings from human and animal studies indic
ating that B is a dynamic trace element which, in physiological amount
s, can affect the metabolism or utilisation of numerous other substanc
es involved in life processes including macrominerals, energy substrat
es such as triglycerides and glucose, nitrogen containing substances s
uch as amino acids and proteins, reactive oxygen species, and estrogen
. Through these effects, B can affect the function or composition of s
everal body systems, including the brain, skeleton and immune system,
generally in a beneficial fashion. Moreover, homeostatic mechanisms ap
parently exist for B because it is rapidly excreted in the urine, does
not accumulate in tissues, and is maintained in a relatively narrow r
ange of concentrations in blood of healthy individuals. Thus, even tho
ugh B has not been conclusively established as essential because a bio
chemical function for it has not been identified, its beneficial actio
ns suggest that an intake of over 1 mg day(-1) (but probably not more
than 13 mg day(-1)) is desirable; diets low in fruits, vegetables, leg
umes and nuts may not provide this amount of B. Boron may be of more p
ractical nutritional importance than currently acknowledged.