Ms. Pearle et al., BOLUS INJECTION V DRIP INFUSION CONTRAST ADMINISTRATION FOR URETERAL STONE TARGETING DURING SHOCKWAVE LITHOTRIPSY, Journal of endourology, 11(3), 1997, pp. 163-166
Intraoperative excretory urography may be used to facilitate stone tar
geting during in situ SWL for ureteral stones, precluding the need for
ureteral catheter placement. We compared bolus injection with drip in
fusion urography for efficacy in stone localization, Twenty-seven pati
ents with normal renal function and a solitary, difficult to visualize
, radiopaque ureteral calculus were randomized to receive intravenous
contrast by either bolus injection (N = 13) or drip infusion (N = 14),
The bolus injection patients received an average of 74 mL of Conray 4
00 contrast over 1 minute; the drip infusion patients received an aver
age of 92 mL of contrast over 15 minutes, After bolus injection, it to
ok an average of 12 minutes to opacify the ureter compared with 14 min
utes after drip infusion (P = 0.62), It took longer to initiate (5 min
utes) and complete (6 minutes) treatment after drip infusion than afte
r bolus injection (P = 0.28 and P = 0.16, respectively), Imaging time
was significantly longer in the infusion group than in the bolus group
(12 v 7 minutes; P = 0.04), Stone-free rates were similar in the two
groups: 100% for the bolus group and 91% for the infusion group, No pa
tient in either group experienced an adverse reaction to the contrast,
Overall, the two methods of contrast administration were equally effi
cacious for stone targeting during SWL, However, bolus injection requi
red lesser amounts of contrast, provided more rapid opacification of t
he ureter, and resulted in an overall shorter procedural time, althoug
h the only statistically significant differences were in imaging time
and contrast volume.