DIRECT HPLC SEPARATION OF BETA-AMINOESTER ENANTIOMERS ON TOTALLY SYNTHETIC CHIRAL STATIONARY PHASES

Authors
GASPARRINI F DACQUARICA I VILLANI C CIMARELLI C PALMIERI G
Citation
F. Gasparrini et al., DIRECT HPLC SEPARATION OF BETA-AMINOESTER ENANTIOMERS ON TOTALLY SYNTHETIC CHIRAL STATIONARY PHASES, BMC. Biomedical chromatography, 11(5), 1997, pp. 317-320
Citations number
45
Categorie Soggetti
Chemistry Analytical","Pharmacology & Pharmacy",Biology,"Biochemical Research Methods
Journal title
BMC. Biomedical chromatography → ACNP
ISSN journal
02693879
Volume
11
Issue
5
Year of publication
1997
Pages
317 - 320
Database
ISI
SICI code
0269-3879(1997)11:5<317:DHSOBE>2.0.ZU;2-F
Abstract
The direct separation of beta-aminoester enantiomers by HPLC on synthe tic chiral stationary phases based on a pi-acidic derivative of trans 1,2-diaminocyclohexane as selector is described. The application of di fferent columns containing the stationary phase with opposite configur ations and in the racemic form to the determination of enantiomeric ex cess in chemically impure samples is demonstrated. (C) 1997 by John Wi ley & Sons, Ltd.