EXPRESSION OF DROSOPHILA-MELANOGASTER GENE ENCODING TRANSCRIPTION FACTOR GAGA IS TISSUE-SPECIFIC AND TEMPERATURE-DEPENDENT

The GAGA factor (GAF) of Drosophila melanogaster encoded by the Tritho rax-like gene is known to maintain expression of many Drosophila genes including homeotic ones, through configuration remodeling of local ch romatin, The complicated transcript pattern of the GAF gene has been r evealed at all stages of development, The study of GAF gene expression in whole flies and in salivary glands and in the brains with adjacent imaginal disks of the third instar larvae showed tissue-specific vari ations in transcript patterns and dependence of these patterns on the temperature of development (14-37 degrees C). (C) 1997 Federation of E uropean Biochemical Societies.