THE EFFECT OF SELENIUM ON ANTIOXIDANT SYSTEM IN ERYTHROCYTES AND LIVER OF THE CARP (CYPRINUS-CARPIO L.)

The effect of selenium-supplemented diet (sodium selenate and selenium yeast) on antioxidant in erthrocytes and liver of the carp (Cyprinus carpio L.) fingerlings was studied. With this goal, the activities of glutathione peroxidase (GSH-Px), catalase (CAT), superoxide dismutase (SOD), glutathione reductase (GR) and glutathione-S-transferase (GST), as well as glutathione (GSH + GSSG) level, were determined. in the gr oup supplemented with sodium selenate, no significant changes in the a ctivity of the above enzymes were recorded in both the erythrocytes an d in the liver, with the exception of GST activity that was significan tly reduced in the plasma compared with the controls. Glutathione cont ent was at the control level. In the group supplemented with selenium- yeast, the activities of GSH-Px, CAT, and SOD were significantly incre ased in erythrocytes, whereas GST activity and plasma content of GSH GSSG were reduced compared with the controls. At the same time, the a ctivities of hepatic SOD and GST were increased compared with the cont rols. These results demonstrate that organically bound selenium (selen ium-yeast) acts more efficiently on antioxidant system of the carp fin gerlings than inorganic selenium salts.