Hypertension is one of the major risk factors for coronary artery dise
ase. This risk is considerably magnified by the presence of left ventr
icular hypertrophy. The likeliest dominant factor in this increased ri
sk is myocardial ischaemia, the recognition of which is of key importa
nce. Antihypertensive agents ideally should also protect against occur
rence of the clinical syndromes associated with coronary artery diseas
e.