THE STUDY OF THE PHOTOKILLING EFFECT AND MECHANISM OF ULTRAFINE TIO2 PARTICLES ON U937 CELLS

Authors
HUANG NP XU MH YUAN CW YU RR
Citation
Np. Huang et al., THE STUDY OF THE PHOTOKILLING EFFECT AND MECHANISM OF ULTRAFINE TIO2 PARTICLES ON U937 CELLS, Journal of photochemistry and photobiology. A, Chemistry, 108(2-3), 1997, pp. 229-233
Citations number
11
Categorie Soggetti
Chemistry Physical
Journal title
Journal of photochemistry and photobiology. A, Chemistry → ACNP
ISSN journal
10106030
Volume
108
Issue
2-3
Year of publication
1997
Pages
229 - 233
Database
ISI
SICI code
1010-6030(1997)108:2-3<229:TSOTPE>2.0.ZU;2-K
Abstract
The killing effect of photoexcited ultrafine TiO2 particles (UFP TiO2) on U937 cells has been studied. The mechanism concerned has been furt her investigated by DNA agarose gel electrophoresis. The electrophorog ram shows that reactive oxygen species produced by photoexcited UFP Ti O2 can damage DNA, which results in cell death. Finally, a new assumpt ion of the way to kill cancer cells is proposed. (C) 1997 Elsevier Sci ence S.A.