Panic disorder (PD) and asthma share many common characteristics and h
ave been found in epidemiological studies to be significantly comorbid
. To investigate possible reasons for this overlapping, the authors ev
aluated 51 patients with asthma, assessing the prevalence of PD and sp
oradic panic attacks, the temporal relationship between these two diso
rders, and the familial risk for PD in the families of asthmatics, The
results showed significantly higher prevalences of PD, sporadic panic
attacks, and social phobia in asthmatics than those reported for the
general population. In 9 (90%) of the asthmatics with PD, asthma appea
red first, Finally, the morbidity risk for PD in families of asthmatic
s with PD (13.5%) was significantly higher than in families of asthmat
ics without evidence of panic (2%), Our results suggest that the high
prevalence of PD in asthmatics might be related to a facilitating effe
ct of asthma on the development of PD in subjects with familial predis
position to PD. (C) 1997 Society of Biological Psychiatry.