SYNTHETIC RECEPTORS FOR URONIC-ACID SALTS BASED ON BICYCLIC GUANIDINIUM AND DEOXYCHOLIC-ACID SUBUNITS

Authors
SEGURA M ALCAZAR V PRADOS P DEMENDOZA J
Citation
M. Segura et al., SYNTHETIC RECEPTORS FOR URONIC-ACID SALTS BASED ON BICYCLIC GUANIDINIUM AND DEOXYCHOLIC-ACID SUBUNITS, Tetrahedron, 53(38), 1997, pp. 13119-13128
Citations number
51
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron → ACNP
ISSN journal
00404020
Volume
53
Issue
38
Year of publication
1997
Pages
13119 - 13128
Database
ISI
SICI code
0040-4020(1997)53:38<13119:SRFUSB>2.0.ZU;2-5
Abstract
Four receptors for uronic acid salts have been prepared using a chiral bicyclic guanidinium unit and deoxycholic acid derivatives as buildin g blocks. Binding constants in CD3CN/CDCl3 ranged from 3200 to 7000 M- 1 for glucuronate and galacturonate salts. Nordeoxycholic-containing r eceptors were found more efficient and moderately selective for glucur onic salts. (C) 1997 Elsevier Science Ltd.