X=Y-ZH SYSTEMS AS POTENTIAL 1,3-DIPOLES .47. TANDEM NUCLEOPHILIC SUBSTITUTION-1,3 DIPOLAR CYCLOADDITION REACTIONS OF OXIMES WITH EPOXIDES AND DIPOLAROPHILES

Authors
MARKANDU J DONDAS HA FREDERICKSON M GRIGG R
Citation
J. Markandu et al., X=Y-ZH SYSTEMS AS POTENTIAL 1,3-DIPOLES .47. TANDEM NUCLEOPHILIC SUBSTITUTION-1,3 DIPOLAR CYCLOADDITION REACTIONS OF OXIMES WITH EPOXIDES AND DIPOLAROPHILES, Tetrahedron, 53(38), 1997, pp. 13165-13176
Citations number
12
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron → ACNP
ISSN journal
00404020
Volume
53
Issue
38
Year of publication
1997
Pages
13165 - 13176
Database
ISI
SICI code
0040-4020(1997)53:38<13165:XSAP1.>2.0.ZU;2-W
Abstract
Regiospecific nucleophilic substitution reactions involving attack of the nitrogen atom of oximes on epoxides are used to generate nitrones which are then trapped in 1,3-dipolar cycloaddition reactions. These t andem processes are shown to be flexible and to have wide synthetic sc ope for the construction of complex molecular frameworks. (C) 1997 Els evier Science Ltd.