SYNTHESIS AND STUDIES OF THE 15-CROWN-5 COMPLEX OF THE SODIUM-SALT OF2-NITROIMIDAZOLE

Authors
DUNCANSON P GRIFFITHS DV MILLER JR
Citation
P. Duncanson et al., SYNTHESIS AND STUDIES OF THE 15-CROWN-5 COMPLEX OF THE SODIUM-SALT OF2-NITROIMIDAZOLE, Tetrahedron, 53(38), 1997, pp. 13177-13182
Citations number
21
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron → ACNP
ISSN journal
00404020
Volume
53
Issue
38
Year of publication
1997
Pages
13177 - 13182
Database
ISI
SICI code
0040-4020(1997)53:38<13177:SASOT1>2.0.ZU;2-0
Abstract
The 15-crown-5 complex of the sodium salt of 2-nitroimidazole has been isolated and its solid state structure determined by X-ray crystallog raphy. This shows bonding interactions between the sodium atom and the imidazolate through a ring nitrogen and one of the nitro-oxygen atoms . The sodium ion is seven co-ordinate and is located slightly out of t he least-squares plane of the crown ether. In solution, the complex ac ts as a naked anion allowing the heterocyclic ring to be N-alkylated u nder mild conditions. (C) 1997 Published by Elsevier Science Ltd.