INTRAVASCULAR LARGE-CELL LYMPHOMA COEXISTING WITHIN HEMANGIOMAS OF THE SKIN

Intravascular lymphomatosis is a rare and peculiar subtype of large ce ll lymphoma. The authors present the pathologic, clinical, and radiolo gic findings of a patient with intravascular large cell lymphoma coexi sting within hemangiomas of the skin. Initially the lymphoma was clini cally confined to the hemangiomas and the patient was closely observed for disease progression. Within 10 months the patient developed disse minated lymphoma involving both adrenals. A clinical remission was ach ieved, but the patient soon relapsed. and despite further chemotherapy he died with disseminated disease 23 months after the initial diagnos is. This report presents the only known case of an intravascular large cell lymphoma coexisting within a vascular lesion and highlights the potential aggressive nature of intravascular lymphomas.