CAPRINE ENTEROTOXEMIA ASSOCIATED WITH CEREBRAL MICROANGIOPATHY

Cerebral microangiopathy is described in naturally occurring clostridi al enterotoxaemia in two goats. The two cases were selected from the f iles of two diagnostic laboratories in Australia, on the basis that th e clinical syndrome and history were consistent with a diagnosis of en terotoxaemia, and that the diagnosis was confirmed by the identificati on of epsilon toxin in intestinal contents. The lesions consisted of a cute perivascular proteinaceous exudate in the brain and bilaterally s ymmetrical foci of encephalomalacia were observed in one of the goats, These brain lesions confirm that Clostridium perfringens type D enter otoxaemia may produce histologically detectable brain changes in goats .