Femoral pseudoaneurysm is a serious complication in drug addicts who h
abitually inject via the groin. A total of 33 drug addicts presenting
with 34 infected femoral pseudoaneurysms were treated in the Departmen
t of Surgery, the University of Hong Kong, Queen Mary Hospital from Ju
ly 1993 to June 1996. There were 27 men and 6 women, with ages ranging
from 23 to 76 years (mean 39.6 years). Positive intraoperative tissue
cultures were seen in 29 (85%), with 17 being pure growth of methicil
lin-sensitive Staphylococcus aureus (MSSA). Twenty-four pseudoaneurysm
s involved the femoral bifurcation and were treated by triple ligation
of the common femoral, superficial femoral, and profunda femoris arte
ries. Seven other limbs underwent ligation of the common femoral arter
y alone, and three had superficial femoral artery ligation. Nineteen l
imbs had the external iliac artery ligated in addition to the femoral
ligation for better proximal control. The mean postoperative ankle-bra
chial index (ABI) was 0.43 and 0.52 in those with triple ligation and
those with single-vessel ligation, respectively. There was no hospital
mortality, and all patients were discharged with a viable limb. The d
uration of follow-up ranged from 2 to 36 months (mean 15.5 months). Fo
ur patients were asymptomatic, but the rest suffered some degree of in
termittent claudication. No delayed limb loss was identified. We concl
ude that systemic antibiotics active against MSSA are the antibiotics
of choice in drug addicts with infected femoral pseudoaneurysms. Ligat
ion and excision of the pseudoaneurysm without revascularization is sa
fe, with acceptable morbidity and a low limb loss rate.