We report a 24-year-old man with eosinophilic fasciitis who presented
with progressive joint contractures of all four limbs, In this patient
, the serum aldolase concentration was elevated while the serum creati
nine kinase concentration was normal. Magnetic resonance imaging showe
d gadolinium enhancement of fascial structures in the lower limbs. Wit
h the clinical improvement by the treat ment with oral corticosteroid,
the aldolase concentration was decreased, and the fascial]al[ hyperin
tensity on magnetic resonance images was reduced. The phenomenon of in
creased an aldolase concentration accompanied by a normal creatinine k
inase concentration may be characteristic of eosinophilic fascitis. Se
rial magnetic resonance images and serum aldolase concentration are us
eful for monitoring the therapeutic response in this condition.