Aj. Fisher et al., SMALL LYMPH-NODES OF THE ABDOMEN, PELVIS, AND RETROPERITONEUM - USEFULNESS OF SONOGRAPHICALLY GUIDED BIOPSY, Radiology, 205(1), 1997, pp. 185-190
PURPOSE: To evaluate the usefulness of sonographically guided percutan
eous biopsy of small lymph nodes in the abdomen, retroperitoneum, and
pelvis. MATERIALS AND METHODS: From May 1995 through January 1997, 35
sonographically guided lymph node biopsies were performed in 34 patien
ts. All biopsies were performed with a 20- (n = 18) or 22-gauge (n = 1
0) self-aspirating needle alone or in combination (n = 7). To determin
e the amount of compression achieved with the transducer, the skin-to-
lesion distance on reference computed tomographic (CT) scans was compa
red with that on sonograms. A biopsy was considered successful if a sp
ecific benign or malignant diagnosis was rendered by the pathologist.
RESULTS: Of 35 sonographically guided biopsies, 30 (86%) were successf
ul. Diagnoses included 26 (74%) cases of carcinoma, three (9%) cases o
f benign reactive lymphocytosis confirmed at open biopsy, and one (3%)
case of a lymph node with a positive acid-fast bacilli stain. The ave
rage lymph node diameter was 2.1 cm (range, 0.9-4.3 cm). With sonograp
hy, a mean of 2.5 needle passes (range, 1-5) were made per biopsy. Tra
nsducer compression reduced the skin-to-lesion distance from an averag
e of 8.8 cm (at CT) to 4.5 cm. CONCLUSION: Sonographic guidance seems
to provide a reasonable alternative to CT in biopsy of small abdominal
, pelvic, and retroperitoneal lymph nodes.