PURPOSE: To evaluate prospectively the feasibility of treating iatroge
nic pneumothorax after fine-needle aspiration biopsy (FNAB) of the lun
g with short-term placement of a small-caliber chest tube and to deter
mine whether a 1-hour clamping trial is adequate to identify patients
with persistent air leak. MATERIALS AND METHODS: All patients undergoi
ng FNAB of lung masses over a 28-month period were entered into the st
udy. Patients with symptomatic, enlarging, or greater than 30% pneumot
horax were treated with an 8-F chest tube, After 2 hours, the chest tu
be was clamped, and if the lung remained expanded for an additional ho
ur, the chest tube was removed and the patients were discharged after
a brief observation period. Patients were followed up by telephone aft
er 24 hours. RESULTS: Three hundred fifteen patients underwent FNAB of
the lung. Sixty-eight patients (22%) developed a pneumothorax. Chest
tubes were placed in 14 patients (4%): Six patients (2%) required admi
ssion to the hospital (four for air leaks), and the other eight patien
ts were treated successfully as outpatients, with removal of the chest
tube before discharge the day of FNAB. CONCLUSION: Patients who devel
op clinically important pneumothorax after FNAB can be safely treated
with short-term, small-caliber chest tubes and require hospital admiss
ion only if they demonstrate evidence of continued air leak.