A case of lymphoepithelial cyst (LEG) of the pancreas is presented. A
48-year-old man complaining of general fatigue was found to have a het
erogeneous water-dense mass protruding from the surface of the pancrea
s on plain computed tomography (CT). Dynamic CT disclosed septa within
the mass. Magnetic resonance imaging (MRI) showed a hypointense mass
on T1-weighted imaging, and a hyperintense mass on T2-weighted imaging
. MRI with gadolinium enhancement revealed septa within the mass. Endo
scopic ultrasonography showed septa and fine echogenic structures with
in the cystic echoic lesion. Endoscopic retrograde pancreatography sho
wed a normal duct system. Distal pancreatectomy with splenectomy was p
erformed, with a suspected diagnosis of cystic neoplasms of the pancre
as. Histopathologic examination disclosed LEC of the pancreas. Our cas
e suggests that LEC should be considered in the differential diagnosis
of cystic neoplasms of the pancreas.