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Results: 1-25 | 26-50 | 51-56
Results: 1-25/56
CENTRAL NICOTINIC RECEPTOR AGONISTS ABT-418, ABT-089, AND (-)-NICOTINE REDUCE DISTRACTIBILITY IN ADULT MONKEYS
Authors: PRENDERGAST MA JACKSON WJ TERRY AV DECKER MW ARNERIC SP BUCCAFUSCO JJ
Citation: Ma. Prendergast et al., CENTRAL NICOTINIC RECEPTOR AGONISTS ABT-418, ABT-089, AND (-)-NICOTINE REDUCE DISTRACTIBILITY IN ADULT MONKEYS, Psychopharmacology, 136(1), 1998, pp. 50-58
AGE-RELATED DIFFERENCES IN DISTRACTIBILITY AND RESPONSE TO METHYLPHENIDATE IN MONKEYS
Authors: PRENDERGAST MA JACKSON WJ TERRY AV KILLE NJ ARNERIC SP DECKER MW BUCCAFUSCO JJ
Citation: Ma. Prendergast et al., AGE-RELATED DIFFERENCES IN DISTRACTIBILITY AND RESPONSE TO METHYLPHENIDATE IN MONKEYS, Cerebral cortex, 8(2), 1998, pp. 164-172
SYNTHESIS AND STRUCTURE-ACTIVITY-RELATIONSHIPS OF PYRIDINE-MODIFIED ANALOGS OF 3-[2-((S)-PYRROLIDINYL)METHOXY]PYRIDINE, A-84543, A POTENT NICOTINIC ACETYLCHOLINE-RECEPTOR AGONIST
Authors: LIN NH GUNN DE LI YH HE Y BAI H RYTHER KB KUNTZWEILER T DONNELLYROBERTS DL ANDERSON DJ CAMPBELL JE SULLIVAN JP ARNERIC SP HOLLADAY MW
Citation: Nh. Lin et al., SYNTHESIS AND STRUCTURE-ACTIVITY-RELATIONSHIPS OF PYRIDINE-MODIFIED ANALOGS OF 3-[2-((S)-PYRROLIDINYL)METHOXY]PYRIDINE, A-84543, A POTENT NICOTINIC ACETYLCHOLINE-RECEPTOR AGONIST, Bioorganic & medicinal chemistry letters, 8(3), 1998, pp. 249-254
STRUCTURE-ACTIVITY STUDIES RELATED TO ABT-594, A POTENT NONOPIOID ANALGESIC AGENT - EFFECT OF PYRIDINE AND AZETIDINE RING SUBSTITUTIONS ON NICOTINIC ACETYLCHOLINE-RECEPTOR BINDING-AFFINITY AND ANALGESIC ACTIVITY IN MICE
Authors: HOLLADAY MW BAI H LI YH LIN NH DAANEN JF RYTHER KB WASICAK JT KINCAID JF HE Y HETTINGER AM HUANG P ANDERSON DJ BANNON AW BUCKLEY MJ CAMPBELL JE DONNELLYROBERTS DL GUNTHER KL KIM DJB KUNTZWEILER TA SULLIVAN JP DECKER MW ARNERIC SP
Citation: Mw. Holladay et al., STRUCTURE-ACTIVITY STUDIES RELATED TO ABT-594, A POTENT NONOPIOID ANALGESIC AGENT - EFFECT OF PYRIDINE AND AZETIDINE RING SUBSTITUTIONS ON NICOTINIC ACETYLCHOLINE-RECEPTOR BINDING-AFFINITY AND ANALGESIC ACTIVITY IN MICE, Bioorganic & medicinal chemistry letters, 8(19), 1998, pp. 2797-2802
THE ROLE OF NEURONAL NICOTINIC ACETYLCHOLINE-RECEPTORS IN ANTINOCICEPTION - EFFECTS OF ABT-594
Authors: DECKER MW CURZON P HOLLADAY MW NIKKEL AL BITNER RS BANNON AW DONNELLYROBERTS DL PUTTFARCKEN PS KUNTZWEILER TA BRIGGS CA WILLIAMS M ARNERIC SP
Citation: Mw. Decker et al., THE ROLE OF NEURONAL NICOTINIC ACETYLCHOLINE-RECEPTORS IN ANTINOCICEPTION - EFFECTS OF ABT-594, J PHYSL-PAR, 92(3-4), 1998, pp. 221-224
RAPID ASSESSMENT OF LIGAND ACTIONS WITH NICOTINIC ACETYLCHOLINE-RECEPTORS USING CALCIUM DYNAMICS AND FLIPR
Authors: KUNTZWEILER TA ARNERIC SP DONNELLYROBERTS DL
Citation: Ta. Kuntzweiler et al., RAPID ASSESSMENT OF LIGAND ACTIONS WITH NICOTINIC ACETYLCHOLINE-RECEPTORS USING CALCIUM DYNAMICS AND FLIPR, Drug development research, 44(1), 1998, pp. 14-20
ROLE OF THE NUCLEUS RAPHE MAGNUS IN ANTINOCICEPTION PRODUCED BY ABT-594 - IMMEDIATE-EARLY GENE RESPONSES POSSIBLY LINKED TO NEURONAL NICOTINIC ACETYLCHOLINE-RECEPTORS ON SEROTONERGIC NEURONS
Authors: BITNER RS NIKKEL AL CURZON P ARNERIC SP BANNON AW DECKER MW
Citation: Rs. Bitner et al., ROLE OF THE NUCLEUS RAPHE MAGNUS IN ANTINOCICEPTION PRODUCED BY ABT-594 - IMMEDIATE-EARLY GENE RESPONSES POSSIBLY LINKED TO NEURONAL NICOTINIC ACETYLCHOLINE-RECEPTORS ON SEROTONERGIC NEURONS, The Journal of neuroscience, 18(14), 1998, pp. 5426-5432
BROAD-SPECTRUM, NONOPIOID ANALGESIC ACTIVITY BY SELECTIVE MODULATION OF NEURONAL NICOTINIC ACETYLCHOLINE-RECEPTORS
Authors: BANNON AW DECKER MW HOLLADAY MW CURZON P DONNELLYROBERTS D PUTTFARCKEN PS BITNER RS DIAZ A DICKENSON AH PORSOLT RD WILLIAMS M ARNERIC SP
Citation: Aw. Bannon et al., BROAD-SPECTRUM, NONOPIOID ANALGESIC ACTIVITY BY SELECTIVE MODULATION OF NEURONAL NICOTINIC ACETYLCHOLINE-RECEPTORS, Science, 279(5347), 1998, pp. 77-81
ABT-594 [(R)-5-(2-AZETIDINYLMETHOXY)-2-CHLOROPYRIDINE] - A NOVEL, ORALLY EFFECTIVE ANALGESIC ACTING VIA NEURONAL NICOTINIC ACETYLCHOLINE-RECEPTORS - I - IN-VITRO CHARACTERIZATION
Authors: DONNELLYROBERTS DL PUTTFARCKEN PS KUNTZWEILER TA BRIGGS CA ANDERSON DJ CAMPBELL JE PIATTONIKAPLAN M MCKENNA DG WASICAK JT HOLLADAY MW WILLIAMS M ARNERIC SP
Citation: Dl. Donnellyroberts et al., ABT-594 [(R)-5-(2-AZETIDINYLMETHOXY)-2-CHLOROPYRIDINE] - A NOVEL, ORALLY EFFECTIVE ANALGESIC ACTING VIA NEURONAL NICOTINIC ACETYLCHOLINE-RECEPTORS - I - IN-VITRO CHARACTERIZATION, The Journal of pharmacology and experimental therapeutics, 285(2), 1998, pp. 777-786
ABT-594 [(R)-5-(2-AZETIDINYLMETHOXY)-2-CHLOROPYRIDINE] - A NOVEL, ORALLY EFFECTIVE ANTINOCICEPTIVE AGENT ACTING VIA NEURONAL NICOTINIC ACETYLCHOLINE-RECEPTORS - II - IN-VIVO CHARACTERIZATION
Authors: BANNON AW DECKER MW CURZON P BUCKLEY MJ KIM DJB RADEK RJ LYNCH JK WASICAK JT LIN NH ARNOLD WH HOLLADAY MW WILLIAMS M ARNERIC SP
Citation: Aw. Bannon et al., ABT-594 [(R)-5-(2-AZETIDINYLMETHOXY)-2-CHLOROPYRIDINE] - A NOVEL, ORALLY EFFECTIVE ANTINOCICEPTIVE AGENT ACTING VIA NEURONAL NICOTINIC ACETYLCHOLINE-RECEPTORS - II - IN-VIVO CHARACTERIZATION, The Journal of pharmacology and experimental therapeutics, 285(2), 1998, pp. 787-794
IDENTIFICATION AND INITIAL STRUCTURE-ACTIVITY-RELATIONSHIPS OF 5-(2-AZETIDINYLMETHOXY)-2-CHLOROPYRIDINE(ABT-594), A POTENT, ORALLY-ACTIVE, NONOPIATE ANALGESIC AGENT ACTING VIA NEURONAL NICOTINIC ACETYLCHOLINE-RECEPTORS
Authors: HOLLADAY MW WASICAK JT LIN NH HE Y RYTHER KB BANNON AW BUCKLEY MJ KIM DJB DECKER MW ANDERSON DJ CAMPBELL JE KUNTZWEILER TA DONNELLYROBERTS DL PIATTONIKAPLAN M BRIGGS CA WILLIAMS M ARNERIC SP
Citation: Mw. Holladay et al., IDENTIFICATION AND INITIAL STRUCTURE-ACTIVITY-RELATIONSHIPS OF 5-(2-AZETIDINYLMETHOXY)-2-CHLOROPYRIDINE(ABT-594), A POTENT, ORALLY-ACTIVE, NONOPIATE ANALGESIC AGENT ACTING VIA NEURONAL NICOTINIC ACETYLCHOLINE-RECEPTORS, Journal of medicinal chemistry, 41(4), 1998, pp. 407-412
UP-REGULATION OF HUMAN ALPHA-7 NICOTINIC RECEPTORS BY CHRONIC TREATMENT WITH ACTIVATOR AND ANTAGONIST LIGANDS
Authors: MOLINARI EJ DELBONO O MESSI ML RENGANATHAN M ARNERIC SP SULLIVAN JP GOPALAKRISHNAN M
Citation: Ej. Molinari et al., UP-REGULATION OF HUMAN ALPHA-7 NICOTINIC RECEPTORS BY CHRONIC TREATMENT WITH ACTIVATOR AND ANTAGONIST LIGANDS, European journal of pharmacology, 347(1), 1998, pp. 131-139
ANTINOCICEPTIVE EFFECTS OF THE NOVEL NEURONAL NICOTINIC ACETYLCHOLINE-RECEPTOR AGONIST, ABT-594, IN MICE
Authors: DECKER MW BANNON AW BUCKLEY MJ KIM DJB HOLLADAY MW RYTHER KB LIN NH WASICAK JT WILLIAMS M ARNERIC SP
Citation: Mw. Decker et al., ANTINOCICEPTIVE EFFECTS OF THE NOVEL NEURONAL NICOTINIC ACETYLCHOLINE-RECEPTOR AGONIST, ABT-594, IN MICE, European journal of pharmacology, 346(1), 1998, pp. 23-33
ABT-594, A NOVEL CHOLINERGIC CHANNEL MODULATOR, IS EFFICACIOUS IN NERVE LIGATION AND DIABETIC NEUROPATHY MODELS OF NEUROPATHIC PAIN
Authors: BANNON AW DECKER MW KIM DJB CAMPBELL JE ARNERIC SP
Citation: Aw. Bannon et al., ABT-594, A NOVEL CHOLINERGIC CHANNEL MODULATOR, IS EFFICACIOUS IN NERVE LIGATION AND DIABETIC NEUROPATHY MODELS OF NEUROPATHIC PAIN, Brain research, 801(1-2), 1998, pp. 158-163
IMPROVEMENT IN ACCURACY OF DELAYED RECALL IN AGED AND NON-AGED, MATURE MONKEYS AFTER INTRAMUSCULAR OR TRANSDERMAL ADMINISTRATION OF THE CNSNICOTINIC RECEPTOR AGONIST ABT-418
Authors: PRENDERGAST MA TERRY AV JACKSON WJ MARSH KC DECKER MW ARNERIC SP BUCCAFUSCO JJ
Citation: Ma. Prendergast et al., IMPROVEMENT IN ACCURACY OF DELAYED RECALL IN AGED AND NON-AGED, MATURE MONKEYS AFTER INTRAMUSCULAR OR TRANSDERMAL ADMINISTRATION OF THE CNSNICOTINIC RECEPTOR AGONIST ABT-418, Psychopharmacology, 130(3), 1997, pp. 276-284
NOVEL 2-(2'-FURO[3,2-B]PYRIDINYL) PYRROLIDINES - POTENT NEURONAL NICOTINIC ACETYLCHOLINE-RECEPTOR LIGANDS
Authors: ELLIOTT RL RYTHER KB ANDERSON DJ PIATTONIKAPLAN M KUNTZWEILER TA DONNELLYROBERTS D ARNERIC SP HOLLADAY MW
Citation: Rl. Elliott et al., NOVEL 2-(2'-FURO[3,2-B]PYRIDINYL) PYRROLIDINES - POTENT NEURONAL NICOTINIC ACETYLCHOLINE-RECEPTOR LIGANDS, Bioorganic & medicinal chemistry letters, 7(21), 1997, pp. 2703-2708
DESIGN OF SUSTAINED-RELEASE MATRIX SYSTEMS FOR A HIGHLY WATER-SOLUBLECOMPOUND, ABT-089
Authors: QIU YH FLOOD K MARSH K CARROLL S TRIVEDI J ARNERIC SP KRILL SL
Citation: Yh. Qiu et al., DESIGN OF SUSTAINED-RELEASE MATRIX SYSTEMS FOR A HIGHLY WATER-SOLUBLECOMPOUND, ABT-089, International journal of pharmaceutics, 157(1), 1997, pp. 43-52
ABT-089 [3-(2(S)-PYRROLIDINYLMETHOXY)-2-METHYLPYRIDINE] - AN ORALLY EFFECTIVE CHOLINERGIC CHANNEL MODULATOR WITH POTENTIAL ONCE-A-DAY DOSING AND CARDIOVASCULAR SAFETY
Authors: ARNERIC SP CAMPBELL JE CARROLL S DAANEN JF HOLLADAY MW JOHNSON P LIN NH MARSH KC PETERSON B QUI YH ROBERTS EM RODRIGUES AD SULLIVAN JP TRIVEDI J WILLIAMS M
Citation: Sp. Arneric et al., ABT-089 [3-(2(S)-PYRROLIDINYLMETHOXY)-2-METHYLPYRIDINE] - AN ORALLY EFFECTIVE CHOLINERGIC CHANNEL MODULATOR WITH POTENTIAL ONCE-A-DAY DOSING AND CARDIOVASCULAR SAFETY, Drug development research, 41(1), 1997, pp. 31-43
ABT-089 [2-METHYL-3-(2-(S)-PYRROLIDINYLMETHOXY) PYRIDINE DIHYDROCHLORIDE] - DISCRIMINATIVE STIMULUS PROPERTIES AND ELECTROPHYSIOLOGICAL ACTIONS
Authors: BRIONI JD KIM DJB ONEILL A BRODIE MS DECKER MW ARNERIC SP
Citation: Jd. Brioni et al., ABT-089 [2-METHYL-3-(2-(S)-PYRROLIDINYLMETHOXY) PYRIDINE DIHYDROCHLORIDE] - DISCRIMINATIVE STIMULUS PROPERTIES AND ELECTROPHYSIOLOGICAL ACTIONS, Drug development research, 40(3), 1997, pp. 259-266
FUNCTIONAL-CHARACTERIZATION OF THE NOVEL NEURONAL NICOTINIC ACETYLCHOLINE-RECEPTOR LIGAND GTS-21 IN-VITRO AND IN-VIVO
Authors: BRIGGS CA ANDERSON DJ BRIONI JD BUCCAFUSCO JJ BUCKLEY MJ CAMPBELL JE DECKER MW DONNELLYROBERTS D ELLIOTT RL GOPALAKRISHNAN M HOLLADAY MW HUI YH JACKSON WJ KIM DJB MARSH KC ONEILL A PRENDERGAST MA RYTHER KB SULLIVAN JP ARNERIC SP
Citation: Ca. Briggs et al., FUNCTIONAL-CHARACTERIZATION OF THE NOVEL NEURONAL NICOTINIC ACETYLCHOLINE-RECEPTOR LIGAND GTS-21 IN-VITRO AND IN-VIVO, Pharmacology, biochemistry and behavior, 57(1-2), 1997, pp. 231-241
ABT-089 [2-METHYL-3(2-(S)-PYRROLIDINYLMETHOXY)PYRIDINE] .1. A POTENT AND SELECTIVE CHOLINERGIC CHANNEL MODULATOR WITH NEUROPROTECTIVE PROPERTIES
Authors: SULLIVAN JP DONNELLYROBERTS D BRIGGS CA ANDERSON DJ GOPALAKRISHNAN M XUE IC PLATTONIKAPLAN M MOLINARI E CAMPBELL JE MCKENNA DG GUNN DE LIN NH RYTHER KB HE Y HOLLADAY MW WONNACOTT S WILLIAMS M ARNERIC SP
Citation: Jp. Sullivan et al., ABT-089 [2-METHYL-3(2-(S)-PYRROLIDINYLMETHOXY)PYRIDINE] .1. A POTENT AND SELECTIVE CHOLINERGIC CHANNEL MODULATOR WITH NEUROPROTECTIVE PROPERTIES, The Journal of pharmacology and experimental therapeutics, 283(1), 1997, pp. 235-246
ABT-089 [2-METHYL-3(2-(S)-PYRROLIDINYLMETHOXY)PYRIDINE DIHYDROCHLORIDE] .2. A NOVEL CHOLINERGIC CHANNEL MODULATOR WITH EFFECTS ON COGNITIVEPERFORMANCE IN RATS AND MONKEYS
Authors: DECKER MW BANNON AW CURZON P GUNTHER KL BRIONI JD HOLLADAY MW LIN NH LI YH DAANEN JF BUCCAFUSCO JJ PRENDERGAST MA JACKSON WJ ARNERIC SP
Citation: Mw. Decker et al., ABT-089 [2-METHYL-3(2-(S)-PYRROLIDINYLMETHOXY)PYRIDINE DIHYDROCHLORIDE] .2. A NOVEL CHOLINERGIC CHANNEL MODULATOR WITH EFFECTS ON COGNITIVEPERFORMANCE IN RATS AND MONKEYS, The Journal of pharmacology and experimental therapeutics, 283(1), 1997, pp. 247-258
EVIDENCE FOR NICOTINIC RECEPTORS POTENTIALLY MODULATING NOCICEPTIVE TRANSMISSION AT THE LEVEL OF THE PRIMARY SENSORY NEURON - STUDIES WITH F11 CELLS
Authors: PUTTFARCKEN PS MANELLI AM ARNERIC SP DONNELLYROBERTS DL
Citation: Ps. Puttfarcken et al., EVIDENCE FOR NICOTINIC RECEPTORS POTENTIALLY MODULATING NOCICEPTIVE TRANSMISSION AT THE LEVEL OF THE PRIMARY SENSORY NEURON - STUDIES WITH F11 CELLS, Journal of neurochemistry, 69(3), 1997, pp. 930-938
STRUCTURE-ACTIVITY STUDIES ON 2-METHYL-3-(2(S)-PYRROLIDINYLMETHOXY)PYRIDINE (ABT-089) - AN ORALLY BIOAVAILABLE 3-PYRIDYL ETHER NICOTINIC ACETYLCHOLINE-RECEPTOR LIGAND WITH COGNITION-ENHANCING PROPERTIES
Authors: LIN NH GUNN DE RYTHER KB GARVEY DS DONNELLYROBERTS DL DECKER MW BRIONI JD BUCKLEY MJ RODRIGUES AD MARSH KG ANDERSON DJ BUCCAFUSCO JJ PRENDERGAST MA SULLIVAN JP WILLIAMS M ARNERIC SP HOLLADAY MW
Citation: Nh. Lin et al., STRUCTURE-ACTIVITY STUDIES ON 2-METHYL-3-(2(S)-PYRROLIDINYLMETHOXY)PYRIDINE (ABT-089) - AN ORALLY BIOAVAILABLE 3-PYRIDYL ETHER NICOTINIC ACETYLCHOLINE-RECEPTOR LIGAND WITH COGNITION-ENHANCING PROPERTIES, Journal of medicinal chemistry, 40(3), 1997, pp. 385-390
2-(ARYLOXYMETHYL)AZACYCLIC ANALOGS AS NOVEL NICOTINIC ACETYLCHOLINE-RECEPTOR (NACHR) LIGANDS
Authors: ELLIOTT RL KOPECKA H GUNN DE LIN NH GARVEY DS RYTHER KB HOLLADAY MW ANDERSON DJ CAMPBELL JE SULLIVAN JP BUCKLEY MJ GUNTHER KL ONEILL AB DECKER MW ARNERIC SP
Citation: Rl. Elliott et al., 2-(ARYLOXYMETHYL)AZACYCLIC ANALOGS AS NOVEL NICOTINIC ACETYLCHOLINE-RECEPTOR (NACHR) LIGANDS, Bioorganic & medicinal chemistry letters, 6(19), 1996, pp. 2283-2288
Risultati: 1-25 | 26-50 | 51-56