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Results: 1-25 | 26-33
Results: 1-25/33
IDENTIFICATION OF LOW-MOLECULAR-WEIGHT GP IIB IIIA ANTAGONISTS THAT BIND PREFERENTIALLY TO ACTIVATED PLATELETS/
Authors: BEDNAR RA GAUL SL HAMILL TG EGBERTSON MS SHAFER JA HARTMAN GD GOULD RJ BEDNAR B
Citation: Ra. Bednar et al., IDENTIFICATION OF LOW-MOLECULAR-WEIGHT GP IIB IIIA ANTAGONISTS THAT BIND PREFERENTIALLY TO ACTIVATED PLATELETS/, The Journal of pharmacology and experimental therapeutics, 285(3), 1998, pp. 1317-1326
NONPEPTIDE GPIIB IIIA INHIBITORS .16. THIENO[2,3-B]THIOPHENE ALPHA-SULFONAMIDES ARE POTENT INHIBITORS OF PLATELET-AGGREGATION/
Authors: PRUGH JD GOULD RJ LYNCH RJ ZHANG GX COOK JJ HOLAHAN MA STRANIERI MT SITKO GR GAUL SL BEDNAR RA BEDNAR B HARTMAN GD
Citation: Jd. Prugh et al., NONPEPTIDE GPIIB IIIA INHIBITORS .16. THIENO[2,3-B]THIOPHENE ALPHA-SULFONAMIDES ARE POTENT INHIBITORS OF PLATELET-AGGREGATION/, Bioorganic & medicinal chemistry letters, 7(7), 1997, pp. 865-870
NONPEPTIDE GLYCOPROTEIN IIB IIIA INHIBITORS .18. INDOLE ALPHA-SULFONAMIDE ACIDS ARE POTENT INHIBITORS OF PLATELET-AGGREGATION/
Authors: BRASHEAR KM COOK JJ BEDNAR B BEDNAR RA GOULD RJ HALCZENKO W HOLAHAN MA LYNCH RJ HARTMAN GD HUTCHINSON JH
Citation: Km. Brashear et al., NONPEPTIDE GLYCOPROTEIN IIB IIIA INHIBITORS .18. INDOLE ALPHA-SULFONAMIDE ACIDS ARE POTENT INHIBITORS OF PLATELET-AGGREGATION/, Bioorganic & medicinal chemistry letters, 7(21), 1997, pp. 2793-2798
REGULATION OF THE CLONED THROMBIN RECEPTOR ON HUMAN PLATELETS
Authors: CONNOLLY TM CONDRA C JOLLY C BEDNAR B KARCZEWSKI J STERN A GOULD RJ
Citation: Tm. Connolly et al., REGULATION OF THE CLONED THROMBIN RECEPTOR ON HUMAN PLATELETS, Thrombosis and haemostasis, 1997, pp. 256-256
ALLOSTERIC MODULATION OF RGD-BINDING SITES IN GP IIB IIIA BY THE ANTIBODY REOPRO(TM)/
Authors: BEDNAR RA CUNNINGHAM ME GAUL SL COOK JJ BEDNAR B GOULD RJ
Citation: Ra. Bednar et al., ALLOSTERIC MODULATION OF RGD-BINDING SITES IN GP IIB IIIA BY THE ANTIBODY REOPRO(TM)/, Thrombosis and haemostasis, 1997, pp. 2697-2697
THE EFFECT OF VARIABILITY IN THE CONCENTRATION OF RECEPTORS AND THE BINDING-AFFINITY OF FIBRINOGEN RECEPTOR ANTAGONISTS ON EFFICACY
Authors: BEDNAR B BEDNAR RA MCQUENEY PA CUNNIGHAM ME LYNCH RJ GAUL SL EGBERTSON MS HARTMAN GD GOULD RJ
Citation: B. Bednar et al., THE EFFECT OF VARIABILITY IN THE CONCENTRATION OF RECEPTORS AND THE BINDING-AFFINITY OF FIBRINOGEN RECEPTOR ANTAGONISTS ON EFFICACY, Thrombosis and haemostasis, 1997, pp. 2698-2698
CHARACTERIZATION OF THE BINDING OF GP IIB IIIA ANTAGONISTS TO ACTIVE AND INACTIVE FORMS OF GP IIB/IIIA AND TO RESTING AND ACTIVATED PLATELETS/
Authors: BEDNAR RA GAUL SL GOULD RJ BEDNAR B
Citation: Ra. Bednar et al., CHARACTERIZATION OF THE BINDING OF GP IIB IIIA ANTAGONISTS TO ACTIVE AND INACTIVE FORMS OF GP IIB/IIIA AND TO RESTING AND ACTIVATED PLATELETS/, Thrombosis and haemostasis, 1997, pp. 2705-2705
KINETIC AND THERMODYNAMIC PARAMETERS OF RGD LIGANDS IN BINDING TO GPIIB IIIA ON PLATELETS/
Authors: CUNNIGHAM ME MCQUENEY PA EGBERTSON MS ASKEW BC BEDNAR RA HARTMAN GH GOULD RJ BEDNAR B
Citation: Me. Cunnigham et al., KINETIC AND THERMODYNAMIC PARAMETERS OF RGD LIGANDS IN BINDING TO GPIIB IIIA ON PLATELETS/, Thrombosis and haemostasis, 1997, pp. 2745-2745
EQUILIBRIUM AND DYNAMICS OF FIBRINOGEN RECEPTORS ON RESTING AND ACTIVATED PLATELETS AND IMPLICATIONS FOR THE SEPARATION OF EFFICACY AND BLEEDING-TIME
Authors: BEDNAR B BEDNAR RA MCQUENEY PA CUNNIGHAM ME EGBERTSON MS ASKEW BC COOK JJ HARTMAN GD GOULD RJ
Citation: B. Bednar et al., EQUILIBRIUM AND DYNAMICS OF FIBRINOGEN RECEPTORS ON RESTING AND ACTIVATED PLATELETS AND IMPLICATIONS FOR THE SEPARATION OF EFFICACY AND BLEEDING-TIME, Thrombosis and haemostasis, 1997, pp. 2757-2757
FLOW CYTOMETRIC MEASUREMENT OF KINETIC AND EQUILIBRIUM BINDING PARAMETERS OF ARGININE-GLYCINE-ASPARTIC ACID LIGANDS IN BINDING TO GLYCOPROTEIN IIB IIIA ON PLATELETS/
Authors: BEDNAR B CUNNINGHAM ME MCQUENEY PA EGBERTSON MS ASKEW BC BEDNAR RA HARTMAN GD GOULD RJ
Citation: B. Bednar et al., FLOW CYTOMETRIC MEASUREMENT OF KINETIC AND EQUILIBRIUM BINDING PARAMETERS OF ARGININE-GLYCINE-ASPARTIC ACID LIGANDS IN BINDING TO GLYCOPROTEIN IIB IIIA ON PLATELETS/, Cytometry, 28(1), 1997, pp. 58-65
ARGININE-GLYCINE-ASPARTIC ACID MIMICS CAN IDENTIFY A TRANSITIONAL ACTIVATION STATE OF RECOMBINANT ALPHA-IIB-BETA-3 IN HUMAN EMBRYONIC KIDNEY 293-CELLS
Authors: ABRAHAM DG NUTT EM BEDNAR RA BEDNAR B GOULD RJ DUONG LT
Citation: Dg. Abraham et al., ARGININE-GLYCINE-ASPARTIC ACID MIMICS CAN IDENTIFY A TRANSITIONAL ACTIVATION STATE OF RECOMBINANT ALPHA-IIB-BETA-3 IN HUMAN EMBRYONIC KIDNEY 293-CELLS, Molecular pharmacology, 52(2), 1997, pp. 227-236
NONPEPTIDE GLYCOPROTEIN IIB IIIA INHIBITORS .17. DESIGN AND SYNTHESISOF ORALLY-ACTIVE, LONG-ACTING NONPEPTIDE FIBRINOGEN RECEPTOR ANTAGONISTS/
Authors: ASKEW BC BEDNAR RA BEDNAR B CLAREMON DA COOK JJ MCINTYRE CJ HUNT CA GOULD RJ LYNCH RJ LYNCH JJ GAUL SL STRANIERI MT SITKO GR HOLAHAN MA GLASS JD HAMILL T GORHAM LM PRUEKSARITANONT T BALDWIN JJ HARTMAN GD
Citation: Bc. Askew et al., NONPEPTIDE GLYCOPROTEIN IIB IIIA INHIBITORS .17. DESIGN AND SYNTHESISOF ORALLY-ACTIVE, LONG-ACTING NONPEPTIDE FIBRINOGEN RECEPTOR ANTAGONISTS/, Journal of medicinal chemistry, 40(12), 1997, pp. 1779-1788
RGD LIGANDS INDUCE A COMMON NEO-EPITOPE UPON BINDING TO ALPHA(IIB)BETA(3) ON PLATELETS
Authors: MCQUENEY PA BOLLAG DM EGBERTSON MS HARTMAN GD GOULD RJ BEDNAR B
Citation: Pa. Mcqueney et al., RGD LIGANDS INDUCE A COMMON NEO-EPITOPE UPON BINDING TO ALPHA(IIB)BETA(3) ON PLATELETS, Molecular biology of the cell, 7, 1996, pp. 1436-1436
A TRANSITIONALLY ACTIVE CONFORMATION OF ALPHA(IIB)BETA(3) IS CAPABLE OF MEDIATING CELL-AGGREGATION
Authors: ABRAHAM DG NUTT EM BEDNAR RA BEDNAR B GOULD RJ DUONG LT
Citation: Dg. Abraham et al., A TRANSITIONALLY ACTIVE CONFORMATION OF ALPHA(IIB)BETA(3) IS CAPABLE OF MEDIATING CELL-AGGREGATION, Molecular biology of the cell, 7, 1996, pp. 1439-1439
NONPEPTIDE GPIIB IIIA INHIBITORS .10. CENTRALLY CONSTRAINED ALPHA-SULFONAMIDES ARE POTENT INHIBITORS OF PLATELET-AGGREGATION/
Authors: EGBERTSON MS HARTMAN GD GOULD RJ BEDNAR B BEDNAR RA COOK JJ GAUL SL HOLAHAN MA LIBBY LA LYNCH JJ LYNCH RJ SITKO GR STRANIERI MT VASSALLO LM
Citation: Ms. Egbertson et al., NONPEPTIDE GPIIB IIIA INHIBITORS .10. CENTRALLY CONSTRAINED ALPHA-SULFONAMIDES ARE POTENT INHIBITORS OF PLATELET-AGGREGATION/, Bioorganic & medicinal chemistry letters, 6(21), 1996, pp. 2519-2524
NONPEPTIDE GLYCOPROTEIN IIB IIIA INHIBITORS .9. CENTRALLY CONSTRAINEDALPHA-SULFONAMIDES ARE USEFUL TOOLS FOR EXPLORING PLATELET RECEPTOR FUNCTION/
Authors: EGBERTSON MS BEDNAR B BEDNAR RA HARTMAN GD GOULD RJ LYNCH RJ VASSALLO LM YOUNG SD
Citation: Ms. Egbertson et al., NONPEPTIDE GLYCOPROTEIN IIB IIIA INHIBITORS .9. CENTRALLY CONSTRAINEDALPHA-SULFONAMIDES ARE USEFUL TOOLS FOR EXPLORING PLATELET RECEPTOR FUNCTION/, Bioorganic & medicinal chemistry letters, 6(12), 1996, pp. 1415-1420
NONRADIATIVE ENERGY-TRANSFER STUDIES OF BLOCK-COPOLYMERS IN SELECTIVESOLVENTS
Authors: BEDNAR B KARASEK L POKORNY J
Citation: B. Bednar et al., NONRADIATIVE ENERGY-TRANSFER STUDIES OF BLOCK-COPOLYMERS IN SELECTIVESOLVENTS, Polymer, 37(23), 1996, pp. 5261-5268
NOVEL MECHANISM FOR LONG-ACTING GPIIB IIIA ANTAGONISTS/
Authors: BEDNAR RA GAUL SL COOK JJ ASKEW BC HARTMAN GD GOULD RJ BEDNAR B
Citation: Ra. Bednar et al., NOVEL MECHANISM FOR LONG-ACTING GPIIB IIIA ANTAGONISTS/, Circulation, 94(8), 1996, pp. 568-568
CHARACTERIZATION OF LIGAND-INDUCED BINDING SIDES ON GPIIB IIIA UPON BINDING OF GPIIB/IIIA ANTAGONISTS USING MONOCLONAL-ANTIBODIES/
Authors: MCQUENEY PA BOLLAG DM HARTMAN GD GOULD RJ BEDNAR B
Citation: Pa. Mcqueney et al., CHARACTERIZATION OF LIGAND-INDUCED BINDING SIDES ON GPIIB IIIA UPON BINDING OF GPIIB/IIIA ANTAGONISTS USING MONOCLONAL-ANTIBODIES/, Circulation, 94(8), 1996, pp. 570-570
DRUG-DEPENDENT ANTIBODIES AGAINST GPIIB IIIA INDUCE THROMBOCYTOPENIA/
Authors: BEDNAR B BEDNAR RA COOK JJ BOLLAG DM CHANG CT GAUL SL MCQUENEY PA EGBERTSON MS HARTMAN GD HOLAHAN MA LYNCH JJ GOULD RJ
Citation: B. Bednar et al., DRUG-DEPENDENT ANTIBODIES AGAINST GPIIB IIIA INDUCE THROMBOCYTOPENIA/, Circulation, 94(8), 1996, pp. 571-571
EVIDENCE FOR AN ACTIVATION-DEPENDENT CHANGE IN CONFORMATION OF THE 7-TRANSMEMBRANE THROMBIN RECEPTOR ON HUMAN PLATELETS
Authors: CONNOLLY TM KARCZEWSKI J JOLLY C BEDNAR B CONDRA C FENG DM GOULD RJ
Citation: Tm. Connolly et al., EVIDENCE FOR AN ACTIVATION-DEPENDENT CHANGE IN CONFORMATION OF THE 7-TRANSMEMBRANE THROMBIN RECEPTOR ON HUMAN PLATELETS, Circulation, 94(8), 1996, pp. 3390-3390
RECOMBINANT GPII IIIA EXPRESSED IN HUMAN EMBRYONIC KIDNEY-CELL LINE (293) IS IN AN ACTIVATED STATE/
Authors: ABRAHAM DG NUTT EM BEDNAR R BEDNAR B GOULD RJ DUONG LT
Citation: Dg. Abraham et al., RECOMBINANT GPII IIIA EXPRESSED IN HUMAN EMBRYONIC KIDNEY-CELL LINE (293) IS IN AN ACTIVATED STATE/, Molecular biology of the cell, 6, 1995, pp. 255-255
THE INTERACTIONS OF MULTIVALENT FIBRINOGEN RECEPTOR ANTAGONISTS WITH PURIFIED GPIIB IIIA AND PLATELETS/
Authors: BEDNAR B BEDNAR RA CHANG CT GAUL SL EGBERTSON MS HARTMAN GD SHAFER JA GOULD RJ
Citation: B. Bednar et al., THE INTERACTIONS OF MULTIVALENT FIBRINOGEN RECEPTOR ANTAGONISTS WITH PURIFIED GPIIB IIIA AND PLATELETS/, The FASEB journal, 9(4), 1995, pp. 838-838
BINDING OF THE FIBRINOGEN RECEPTOR ANTAGONIST MK-0383 TO PURIFIED GPIIB IIIA AND TO PLATELETS/
Authors: BEDNAR RA BEDNAR B GAUL SL CHANG CT HAMILL T EGBERTSON MS HALCZENKO W HARTMAN GD SHAFTER JA GOULD RJ
Citation: Ra. Bednar et al., BINDING OF THE FIBRINOGEN RECEPTOR ANTAGONIST MK-0383 TO PURIFIED GPIIB IIIA AND TO PLATELETS/, The FASEB journal, 9(3), 1995, pp. 56-56
PLATELET-AGGREGATION MONITORED IN A 96-WELL MICROPLATE READER IS USEFUL FOR EVALUATION OF PLATELET AGONISTS AND ANTAGONISTS
Authors: BEDNAR B CONDRA C GOULD RJ CONNOLLY TM
Citation: B. Bednar et al., PLATELET-AGGREGATION MONITORED IN A 96-WELL MICROPLATE READER IS USEFUL FOR EVALUATION OF PLATELET AGONISTS AND ANTAGONISTS, Thrombosis research, 77(5), 1995, pp. 453-463
Risultati: 1-25 | 26-33