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DELETION OF A HIGHLY MOTIONAL RESIDUE AFFECTS FORMATION OF THE MICHAELIS COMPLEX FOR ESCHERICHIA-COLI DIHYDROFOLATE-REDUCTASE
Authors: MILLER GP BENKOVIC SJ
Citation: Gp. Miller et Sj. Benkovic, DELETION OF A HIGHLY MOTIONAL RESIDUE AFFECTS FORMATION OF THE MICHAELIS COMPLEX FOR ESCHERICHIA-COLI DIHYDROFOLATE-REDUCTASE, Biochemistry, 37(18), 1998, pp. 6327-6335
STRENGTH OF AN INTERLOOP HYDROGEN-BOND DETERMINES THE KINETIC PATHWAYIN CATALYSIS BY ESCHERICHIA-COLI DIHYDROFOLATE-REDUCTASE
Authors: MILLER GP BENKOVIC SJ
Citation: Gp. Miller et Sj. Benkovic, STRENGTH OF AN INTERLOOP HYDROGEN-BOND DETERMINES THE KINETIC PATHWAYIN CATALYSIS BY ESCHERICHIA-COLI DIHYDROFOLATE-REDUCTASE, Biochemistry, 37(18), 1998, pp. 6336-6342
STRETCHING EXERCISES - FLEXIBILITY IN DIHYDROFOLATE-REDUCTASE CATALYSIS
Authors: MILLER GP BENKOVIC SJ
Citation: Gp. Miller et Sj. Benkovic, STRETCHING EXERCISES - FLEXIBILITY IN DIHYDROFOLATE-REDUCTASE CATALYSIS, Chemistry & biology, 5(5), 1998, pp. 105-113
DESIGN, SYNTHESIS, AND EVALUATION OF POTENTIAL GAR AND AICAR TRANSFORMYLASE INHIBITORS
Authors: BOGER DL KOCHANNY MJ CAI H WYATT D KITOS PA WARREN MS RAMCHARAN J GOOLJARSINGH LT BENKOVIC SJ
Citation: Dl. Boger et al., DESIGN, SYNTHESIS, AND EVALUATION OF POTENTIAL GAR AND AICAR TRANSFORMYLASE INHIBITORS, Bioorganic & medicinal chemistry, 6(6), 1998, pp. 643-659
A PERSPECTIVE ON BIOLOGICAL CATALYSIS
Authors: BENKOVIC SJ
Citation: Sj. Benkovic, A PERSPECTIVE ON BIOLOGICAL CATALYSIS, Journal of physical organic chemistry, 11(8-9), 1998, pp. 508-511
HYBRID ENZYMES - MANIPULATING ENZYME DESIGN
Authors: NIXON AE OSTERMEIER M BENKOVIC SJ
Citation: Ae. Nixon et al., HYBRID ENZYMES - MANIPULATING ENZYME DESIGN, Trends in biotechnology, 16(6), 1998, pp. 258-264
A CELL-CYCLE-REGULATED ADENINE DNA METHYLTRANSFERASE FROM CAULOBACTER-CRESCENTUS PROCESSIVELY METHYLATES GANTC SITES ON HEMIMETHYLATED DNA
Authors: BERDIS AJ LEE I COWARD JK STEPHENS C WRIGHT R SHAPIRO L BENKOVIC SJ
Citation: Aj. Berdis et al., A CELL-CYCLE-REGULATED ADENINE DNA METHYLTRANSFERASE FROM CAULOBACTER-CRESCENTUS PROCESSIVELY METHYLATES GANTC SITES ON HEMIMETHYLATED DNA, Proceedings of the National Academy of Sciences of the United Statesof America, 95(6), 1998, pp. 2874-2879
SIMULTANEOUS FORMATION OF FUNCTIONAL LEADING AND LAGGING-STRAND HOLOENZYME COMPLEXES ON A SMALL, DEFINED DNA SUBSTRATE
Authors: BERDIS AJ BENKOVIC SJ
Citation: Aj. Berdis et Sj. Benkovic, SIMULTANEOUS FORMATION OF FUNCTIONAL LEADING AND LAGGING-STRAND HOLOENZYME COMPLEXES ON A SMALL, DEFINED DNA SUBSTRATE, Proceedings of the National Academy of Sciences of the United Statesof America, 95(19), 1998, pp. 11128-11133
A PH-DEPENDENT STABILIZATION OF AN ACTIVE-SITE LOOP OBSERVED FROM LOWAND HIGH PH CRYSTAL-STRUCTURES OF MUTANT MONOMERIC GLYCINAMIDE RIBONUCLEOTIDE TRANSFORMYLASE AT 1.8 TO 1.9 ANGSTROM
Authors: SU Y YAMASHITA MM GREASLEY SE MULLEN CA SHIM JH JENNINGS PA BENKOVIC SJ WILSON LA
Citation: Y. Su et al., A PH-DEPENDENT STABILIZATION OF AN ACTIVE-SITE LOOP OBSERVED FROM LOWAND HIGH PH CRYSTAL-STRUCTURES OF MUTANT MONOMERIC GLYCINAMIDE RIBONUCLEOTIDE TRANSFORMYLASE AT 1.8 TO 1.9 ANGSTROM, Journal of Molecular Biology, 281(3), 1998, pp. 485-499
EFFECT OF ACCESSORY PROTEINS ON T4 DNA-POLYMERASE REPLICATION FIDELITY
Authors: KROUTIL LC FREY MW KABOORD BF KUNKEL TA BENKOVIC SJ
Citation: Lc. Kroutil et al., EFFECT OF ACCESSORY PROTEINS ON T4 DNA-POLYMERASE REPLICATION FIDELITY, Journal of Molecular Biology, 278(1), 1998, pp. 135-146
SOLVATION, REORGANIZATION ENERGY, AND BIOLOGICAL CATALYSIS
Authors: CANNON WR BENKOVIC SJ
Citation: Wr. Cannon et Sj. Benkovic, SOLVATION, REORGANIZATION ENERGY, AND BIOLOGICAL CATALYSIS, The Journal of biological chemistry, 273(41), 1998, pp. 26257-26260
PURIFICATION, CHARACTERIZATION, AND KINETIC-STUDIES OF A SOLUBLE BACTEROIDES-FRAGILIS METALLO-BETA-LACTAMASE THAT PROVIDES MULTIPLE ANTIBIOTIC-RESISTANCE
Authors: WANG ZG BENKOVIC SJ
Citation: Zg. Wang et Sj. Benkovic, PURIFICATION, CHARACTERIZATION, AND KINETIC-STUDIES OF A SOLUBLE BACTEROIDES-FRAGILIS METALLO-BETA-LACTAMASE THAT PROVIDES MULTIPLE ANTIBIOTIC-RESISTANCE, The Journal of biological chemistry, 273(35), 1998, pp. 22402-22408
ACTIVE-SITE TOPOLOGY OF ARTIFICIAL PEROXIDASE-LIKE HEMOPROTEINS BASEDON ANTIBODIES CONSTRUCTED FROM A SPECIFICALLY DESIGNED ORTHO-CARBOXY-SUBSTITUTED TETRAARYLPORPHYRIN
Authors: DELAUZON S QUILEZ R LION L DESFOSSES B DESFOSSES B LEE I SARI MA BENKOVIC SJ MANSUY D MAHY JP
Citation: S. Delauzon et al., ACTIVE-SITE TOPOLOGY OF ARTIFICIAL PEROXIDASE-LIKE HEMOPROTEINS BASEDON ANTIBODIES CONSTRUCTED FROM A SPECIFICALLY DESIGNED ORTHO-CARBOXY-SUBSTITUTED TETRAARYLPORPHYRIN, European journal of biochemistry, 257(1), 1998, pp. 121-130
CLAMP SUBUNIT DISSOCIATION DICTATES BACTERIOPHAGE-T4 DNA-POLYMERASE HOLOENZYME DISASSEMBLY
Authors: SOUMILLION P SEXTON DJ BENKOVIC SJ
Citation: P. Soumillion et al., CLAMP SUBUNIT DISSOCIATION DICTATES BACTERIOPHAGE-T4 DNA-POLYMERASE HOLOENZYME DISASSEMBLY, Biochemistry, 37(7), 1998, pp. 1819-1827
KINETIC CHARACTERIZATION OF A BACTERIOPHAGE-T4 ANTIMUTATOR DNA-POLYMERASE
Authors: WU P NOSSAL N BENKOVIC SJ
Citation: P. Wu et al., KINETIC CHARACTERIZATION OF A BACTERIOPHAGE-T4 ANTIMUTATOR DNA-POLYMERASE, Biochemistry (Easton), 37(42), 1998, pp. 14748-14755
EVALUATION OF THE KINETIC MECHANISM OF ESCHERICHIA-COLI GLYCINAMIDE RIBONUCLEOTIDE TRANSFORMYLASE
Authors: SHIM JH BENKOVIC SJ
Citation: Jh. Shim et Sj. Benkovic, EVALUATION OF THE KINETIC MECHANISM OF ESCHERICHIA-COLI GLYCINAMIDE RIBONUCLEOTIDE TRANSFORMYLASE, Biochemistry, 37(24), 1998, pp. 8776-8782
DISSECTING THE ORDER OF BACTERIOPHAGE-T4 DNA-POLYMERASE HOLOENZYME ASSEMBLY
Authors: SEXTON DJ KABOORD BF BERDIS AJ CARVER TE BENKOVIC SJ
Citation: Dj. Sexton et al., DISSECTING THE ORDER OF BACTERIOPHAGE-T4 DNA-POLYMERASE HOLOENZYME ASSEMBLY, Biochemistry, 37(21), 1998, pp. 7749-7756
DEVELOPMENT OF AN INTERNALLY QUENCHED FLUORESCENT SUBSTRATE FOR ESCHERICHIA-COLI LEADER PEPTIDASE
Authors: ZHONG WY BENKOVIC SJ
Citation: Wy. Zhong et Sj. Benkovic, DEVELOPMENT OF AN INTERNALLY QUENCHED FLUORESCENT SUBSTRATE FOR ESCHERICHIA-COLI LEADER PEPTIDASE, Analytical biochemistry, 255(1), 1998, pp. 66-73
DIRECT OBSERVATION OF AN ENZYME-BOUND INTERMEDIATE IN THE CATALYTIC CYCLE OF THE METALLO-BETA-LACTAMASE FROM BACTEROIDES-FRAGILIS
Authors: WANG ZG FAST W BENKOVIC SJ
Citation: Zg. Wang et al., DIRECT OBSERVATION OF AN ENZYME-BOUND INTERMEDIATE IN THE CATALYTIC CYCLE OF THE METALLO-BETA-LACTAMASE FROM BACTEROIDES-FRAGILIS, Journal of the American Chemical Society, 120(41), 1998, pp. 10788-10789
MECHANISMS RESEARCH HIGHLIGHTS AT THE CHEMISTRY BIOLOGY INTERFACE - EDITORIAL OVERVIEW/
Authors: BENKOVIC SJ WALSH CT
Citation: Sj. Benkovic et Ct. Walsh, MECHANISMS RESEARCH HIGHLIGHTS AT THE CHEMISTRY BIOLOGY INTERFACE - EDITORIAL OVERVIEW/, CURRENT OPINION IN CHEMICAL BIOLOGY, 1(3), 1997, pp. 289-291
ASSEMBLY AND DISASSEMBLY OF DNA-POLYMERASE HOLOENZYME
Authors: SEXTON DJ BERDIS AJ BENKOVIC SJ
Citation: Dj. Sexton et al., ASSEMBLY AND DISASSEMBLY OF DNA-POLYMERASE HOLOENZYME, CURRENT OPINION IN CHEMICAL BIOLOGY, 1(3), 1997, pp. 316-322
10-FORMYL-5,8,10-TRIDEAZAFOLIC ACID (10-FORMYL-TDAF) - A POTENT INHIBITOR OF GLYCINAMIDE RIBONUCLEOTIDE TRANSFORMYLASE
Authors: BOGER DL HAYNES NE KITOS PA WARREN MS RAMCHARAN J MAROLEWSKI AE BENKOVIC SJ
Citation: Dl. Boger et al., 10-FORMYL-5,8,10-TRIDEAZAFOLIC ACID (10-FORMYL-TDAF) - A POTENT INHIBITOR OF GLYCINAMIDE RIBONUCLEOTIDE TRANSFORMYLASE, Bioorganic & medicinal chemistry, 5(9), 1997, pp. 1817-1830
FUNCTIONALIZED ANALOGS OF 5,8,10-TRIDEAZAFOLATE AS POTENTIAL INHIBITORS OF GAR TFASE OR AICAR TFASE
Authors: BOGER DL HAYNES NE WARREN MS GOOLJARSINGH LT RAMCHARAN J KITOS PA BENKOVIC SJ
Citation: Dl. Boger et al., FUNCTIONALIZED ANALOGS OF 5,8,10-TRIDEAZAFOLATE AS POTENTIAL INHIBITORS OF GAR TFASE OR AICAR TFASE, Bioorganic & medicinal chemistry, 5(9), 1997, pp. 1831-1838
FUNCTIONALIZED ANALOGS OF 5,8,10-TRIDEAZAFOLATE - DEVELOPMENT OF AN ENZYME-ASSEMBLED TIGHT-BINDING INHIBITOR OF GAR TFASE AND A POTENTIAL IRREVERSIBLE INHIBITOR OF AICAR TFASE
Authors: BOGER DL HAYNES NE WARREN MS RAMCHARAN J KITOS PA BENKOVIC SJ
Citation: Dl. Boger et al., FUNCTIONALIZED ANALOGS OF 5,8,10-TRIDEAZAFOLATE - DEVELOPMENT OF AN ENZYME-ASSEMBLED TIGHT-BINDING INHIBITOR OF GAR TFASE AND A POTENTIAL IRREVERSIBLE INHIBITOR OF AICAR TFASE, Bioorganic & medicinal chemistry, 5(9), 1997, pp. 1839-1846
ABENZYL 10-FORMYL-TRIDEAZAFOLIC ACID (ABENZYL 10-FORMYL-TDAF) - AN EFFECTIVE INHIBITOR OF GLYCINAMIDE RIBONUCLEOTIDE TRANSFORMYLASE
Authors: BOGER DL HAYNES NE WARREN MS RAMCHARAN J MAROLEWSKI AE KITOS PA BENKOVIC SJ
Citation: Dl. Boger et al., ABENZYL 10-FORMYL-TRIDEAZAFOLIC ACID (ABENZYL 10-FORMYL-TDAF) - AN EFFECTIVE INHIBITOR OF GLYCINAMIDE RIBONUCLEOTIDE TRANSFORMYLASE, Bioorganic & medicinal chemistry, 5(9), 1997, pp. 1847-1852
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