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Results: 1-20 |
Results: 20
A MUTATION AT POSITION 190 OF HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 REVERSE-TRANSCRIPTASE INTERACTS WITH MUTATIONS AT POSITION-74 AND POSITION-75 VIA THE TEMPLATE PRIMER
Authors: BOYER PL GAO HQ HUGHES SH
Citation: Pl. Boyer et al., A MUTATION AT POSITION 190 OF HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 REVERSE-TRANSCRIPTASE INTERACTS WITH MUTATIONS AT POSITION-74 AND POSITION-75 VIA THE TEMPLATE PRIMER, Antimicrobial agents and chemotherapy, 42(2), 1998, pp. 447-452
HYBRID TY1 HIV-1 ELEMENTS USED TO DETECT INHIBITORS AND MONITOR THE ACTIVITY OF HIV-1 REVERSE-TRANSCRIPTASE/
Authors: NISSLEY DV BOYER PL GARFINKEL DJ HUGHES SH STRATHERN JN
Citation: Dv. Nissley et al., HYBRID TY1 HIV-1 ELEMENTS USED TO DETECT INHIBITORS AND MONITOR THE ACTIVITY OF HIV-1 REVERSE-TRANSCRIPTASE/, Proceedings of the National Academy of Sciences of the United Statesof America, 95(23), 1998, pp. 13905-13910
EFFECTS OF MUTATIONS IN THE POLYMERASE DOMAIN ON THE POLYMERASE, RNASE-H AND STRAND TRANSFER ACTIVITIES OF HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 REVERSE-TRANSCRIPTASE
Authors: GAO HQ BOYER PL ARNOLD E HUGHES SH
Citation: Hq. Gao et al., EFFECTS OF MUTATIONS IN THE POLYMERASE DOMAIN ON THE POLYMERASE, RNASE-H AND STRAND TRANSFER ACTIVITIES OF HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 REVERSE-TRANSCRIPTASE, Journal of Molecular Biology, 277(3), 1998, pp. 559-572
MOLECULAR MODELING OF HIV-1 REVERSE-TRANSCRIPTASE DRUG-RESISTANT MUTANT STRAINS - IMPLICATIONS FOR THE MECHANISM OF POLYMERASE ACTION
Authors: SMITH MBK MICHEJDA CJ HUGHES SH BOYER PL JANSSEN PAJ ANDRIES K BUCKHEIT RW SMITH RH
Citation: Mbk. Smith et al., MOLECULAR MODELING OF HIV-1 REVERSE-TRANSCRIPTASE DRUG-RESISTANT MUTANT STRAINS - IMPLICATIONS FOR THE MECHANISM OF POLYMERASE ACTION, Protein engineering, 10(12), 1997, pp. 1379-1383
SUBUNIT-SPECIFIC MUTAGENESIS OF THE CYSTEINE-280 RESIDUE OF THE REVERSE-TRANSCRIPTASE OF HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 - EFFECTS ON SENSITIVITY TO A SPECIFIC INHIBITOR OF THE RNASE-H ACTIVITY
Authors: LOYA S GAO HQ AVIDAN O BOYER PL HUGHES SH HIZI A
Citation: S. Loya et al., SUBUNIT-SPECIFIC MUTAGENESIS OF THE CYSTEINE-280 RESIDUE OF THE REVERSE-TRANSCRIPTASE OF HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 - EFFECTS ON SENSITIVITY TO A SPECIFIC INHIBITOR OF THE RNASE-H ACTIVITY, Journal of virology, 71(7), 1997, pp. 5668-5672
SYNTHESIS AND BIOLOGICAL-ACTIVITY OF NOVEL NONNUCLEOSIDE INHIBITORS OF HIV-1 REVERSE-TRANSCRIPTASE - 2-ARYL-SUBSTITUTED BENZIMIDAZOLES
Authors: ROTH T MORNINGSTAR ML BOYER PL HUGHES SH BUCKHEIT RW MICHEJDA CJ
Citation: T. Roth et al., SYNTHESIS AND BIOLOGICAL-ACTIVITY OF NOVEL NONNUCLEOSIDE INHIBITORS OF HIV-1 REVERSE-TRANSCRIPTASE - 2-ARYL-SUBSTITUTED BENZIMIDAZOLES, Journal of medicinal chemistry, 40(26), 1997, pp. 4199-4207
NUCLEOSIDE-ANALOG RESISTANCE INVOLVES THE P66 SUBUNIT OF HIV-1 RT
Authors: BOYER PL HUGHES SH
Citation: Pl. Boyer et Sh. Hughes, NUCLEOSIDE-ANALOG RESISTANCE INVOLVES THE P66 SUBUNIT OF HIV-1 RT, Nature structural biology, 3(7), 1996, pp. 579-580
CRYSTAL-STRUCTURES OF 8-CL AND 9-CL TIBO COMPLEXED WITH WILD-TYPE HIV-1 RT AND 8-CL TIBO COMPLEXED WITH THE TYR181CYS HIV-1 RT DRUG-RESISTANT MUTANT
Authors: DAS K DING JP HSIOU Y CLARK AD MOEREELS H KOYMANS L ANDRIES K PAUWELS R JANSSEN PAJ BOYER PL CLARK P SMITH RH SMITH MBK MICHEJDA CJ HUGHES SH ARNOLD E
Citation: K. Das et al., CRYSTAL-STRUCTURES OF 8-CL AND 9-CL TIBO COMPLEXED WITH WILD-TYPE HIV-1 RT AND 8-CL TIBO COMPLEXED WITH THE TYR181CYS HIV-1 RT DRUG-RESISTANT MUTANT, Journal of Molecular Biology, 264(5), 1996, pp. 1085-1100
GROWTH DURING HYPOXIA - METABOLIC RESPONSES TO ANEMIC HYPOXIA
Authors: BOZZINI CE FRIEDMAN SM BOYER PL LEZON CE BARCELO AC ALIPPI RM
Citation: Ce. Bozzini et al., GROWTH DURING HYPOXIA - METABOLIC RESPONSES TO ANEMIC HYPOXIA, Journal of dental research, 75(5), 1996, pp. 1069-1069
MECHANISMS OF RESISTANCE OF HIV-1 REVERSE-TRANSCRIPTASE TO NUCLEOSIDEAND NONNUCLEOSIDE INHIBITORS
Authors: BOYER PL TANTILLO C DING J FERRIS AL CLARK P ARNOLD E HUGHES SH
Citation: Pl. Boyer et al., MECHANISMS OF RESISTANCE OF HIV-1 REVERSE-TRANSCRIPTASE TO NUCLEOSIDEAND NONNUCLEOSIDE INHIBITORS, Journal of acquired immune deficiency syndromes and human retrovirology, 10, 1995, pp. 6-6
THE ROLE OF NUCLEIC-ACID IN THE RESISTANCE OF HIV-1 REVERSE-TRANSCRIPTASE TO NUCLEOSIDE AND NONNUCLEOSIDE INHIBITORS
Authors: ARNOLD E DAS K DING JP HSIOU Y TANTILLO C ROY BM YADAV P ZHANG WY LENTZ K CLARK AD BOYER PL HUGHES SH MITSUYA H MELLORS J KLEIM JP ROSNER M MOEREELS HR KOYMANS L ANDRIES K PAUWELS R JANSSEN PAJ
Citation: E. Arnold et al., THE ROLE OF NUCLEIC-ACID IN THE RESISTANCE OF HIV-1 REVERSE-TRANSCRIPTASE TO NUCLEOSIDE AND NONNUCLEOSIDE INHIBITORS, Journal of acquired immune deficiency syndromes and human retrovirology, 10, 1995, pp. 7-7
MOLECULAR MODELING STUDIES OF HIV-1 REVERSE-TRANSCRIPTASE NONNUCLEOSIDE INHIBITORS - TOTAL-ENERGY OF COMPLEXATION AS A PREDICTOR OF DRUG PLACEMENT AND ACTIVITY
Authors: SMITH MBK ROUZER CA TANEYHILL LA SMITH NA HUGHES SH BOYER PL JANSSEN PAJ MOEREELS H KOYMANS L ARNOLD E DING JP DAS K ZHANG WY MICHEJDA CJ SMITH RH
Citation: Mbk. Smith et al., MOLECULAR MODELING STUDIES OF HIV-1 REVERSE-TRANSCRIPTASE NONNUCLEOSIDE INHIBITORS - TOTAL-ENERGY OF COMPLEXATION AS A PREDICTOR OF DRUG PLACEMENT AND ACTIVITY, Protein science, 4(10), 1995, pp. 2203-2222
ISOLATION AND CHARACTERIZATION OF THE CHICKEN C-SNO GENE
Authors: GIVOL I BOYER PL HUGHES SH
Citation: I. Givol et al., ISOLATION AND CHARACTERIZATION OF THE CHICKEN C-SNO GENE, Gene, 156(2), 1995, pp. 271-276
ANALYSIS OF MUTATIONS AT POSITION-184 IN REVERSE-TRANSCRIPTASE OF HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1
Authors: BOYER PL HUGHES SH
Citation: Pl. Boyer et Sh. Hughes, ANALYSIS OF MUTATIONS AT POSITION-184 IN REVERSE-TRANSCRIPTASE OF HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1, Antimicrobial agents and chemotherapy, 39(7), 1995, pp. 1624-1628
RESISTANCE TO 1-[(2-HYDROXYETHOXY)METHYL]-6-(PHENYLTHIO)THYMINE DERIVATIVES IS GENERATED BY MUTATIONS AT MULTIPLE SITES IN THE HIV-1 REVERSE-TRANSCRIPTASE
Authors: BUCKHEIT RW FLIAKASBOLTZ V YEAGYBARGO S WEISLOW O MAYERS DL BOYER PL HUGHES SH PAN BC CHU SH BADER JP
Citation: Rw. Buckheit et al., RESISTANCE TO 1-[(2-HYDROXYETHOXY)METHYL]-6-(PHENYLTHIO)THYMINE DERIVATIVES IS GENERATED BY MUTATIONS AT MULTIPLE SITES IN THE HIV-1 REVERSE-TRANSCRIPTASE, Virology, 210(1), 1995, pp. 186-193
ENZYMATIC-PROPERTIES OF 2 MUTANTS OF REVERSE-TRANSCRIPTASE OF HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 (TYROSINE-181 -] ISOLEUCINE AND TYROSINE-188 -] LEUCINE), RESISTANT TO NONNUCLEOSIDE INHIBITORS
Authors: LOYA S BAKHANASHVILI M TAL R HUGHES SH BOYER PL HIZI A
Citation: S. Loya et al., ENZYMATIC-PROPERTIES OF 2 MUTANTS OF REVERSE-TRANSCRIPTASE OF HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 (TYROSINE-181 -] ISOLEUCINE AND TYROSINE-188 -] LEUCINE), RESISTANT TO NONNUCLEOSIDE INHIBITORS, AIDS research and human retroviruses, 10(8), 1994, pp. 939-946
SUBUNIT SPECIFICITY OF MUTATIONS THAT CONFER RESISTANCE TO NONNUCLEOSIDE INHIBITORS IN HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 REVERSE-TRANSCRIPTASE
Authors: BOYER PL DING JP ARNOLD E HUGHES SH
Citation: Pl. Boyer et al., SUBUNIT SPECIFICITY OF MUTATIONS THAT CONFER RESISTANCE TO NONNUCLEOSIDE INHIBITORS IN HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 REVERSE-TRANSCRIPTASE, Antimicrobial agents and chemotherapy, 38(9), 1994, pp. 1909-1914
SENSITIVITY OF WILD-TYPE HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 REVERSE-TRANSCRIPTASE TO DIDEOXYNUCLEOTIDES DEPENDS ON TEMPLATE LENGTH - THE SENSITIVITY OF DRUG-RESISTANT MUTANTS DOES NOT
Authors: BOYER PL TANTILLO C JACOBOMOLINA A NANNI RG DING JP ARNOLD E HUGHES SH
Citation: Pl. Boyer et al., SENSITIVITY OF WILD-TYPE HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 REVERSE-TRANSCRIPTASE TO DIDEOXYNUCLEOTIDES DEPENDS ON TEMPLATE LENGTH - THE SENSITIVITY OF DRUG-RESISTANT MUTANTS DOES NOT, Proceedings of the National Academy of Sciences of the United Statesof America, 91(11), 1994, pp. 4882-4886
LOCATIONS OF ANTI-AIDS DRUG-BINDING SITES AND RESISTANCE MUTATIONS INTHE 3-DIMENSIONAL STRUCTURE OF HIV-1 REVERSE-TRANSCRIPTASE - IMPLICATIONS FOR MECHANISMS OF DRUG-INHIBITION AND RESISTANCE
Authors: TANTILLO C DING JP JACOBOMOLINA A NANNI RG BOYER PL HUGHES SH PAUWELS R ANDRIES K JANSSEN PAJ ARNOLD E
Citation: C. Tantillo et al., LOCATIONS OF ANTI-AIDS DRUG-BINDING SITES AND RESISTANCE MUTATIONS INTHE 3-DIMENSIONAL STRUCTURE OF HIV-1 REVERSE-TRANSCRIPTASE - IMPLICATIONS FOR MECHANISMS OF DRUG-INHIBITION AND RESISTANCE, Journal of Molecular Biology, 243(3), 1994, pp. 369-387
MUTATIONAL ANALYSIS OF THE FINGERS AND PALM SUBDOMAINS OF HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 (HIV-1) REVERSE-TRANSCRIPTASE
Authors: BOYER PL FERRIS AL CLARK P WHITMER J FRANK P TANTILLO C ARNOLD E HUGHES SH
Citation: Pl. Boyer et al., MUTATIONAL ANALYSIS OF THE FINGERS AND PALM SUBDOMAINS OF HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 (HIV-1) REVERSE-TRANSCRIPTASE, Journal of Molecular Biology, 243(3), 1994, pp. 472-483
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