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Results: 1-19 |
Results: 19
STRUCTURE OF MALONIC ACID-BASED INHIBITORS BOUND TO HUMAN NEUTROPHIL COLLAGENASE - A NEW BINDING MODE EXPLAINS APPARENTLY ANOMALOUS DATA
Authors: BRANDSTETTER H ENGH RA VONROEDERN EG MORODER L HUBER R BODE W GRAMS F
Citation: H. Brandstetter et al., STRUCTURE OF MALONIC ACID-BASED INHIBITORS BOUND TO HUMAN NEUTROPHIL COLLAGENASE - A NEW BINDING MODE EXPLAINS APPARENTLY ANOMALOUS DATA, Protein science, 7(6), 1998, pp. 1303-1309
DESIGN AND SYNTHESIS OF MALONIC ACID-BASED INHIBITORS OF HUMAN NEUTROPHIL COLLAGENASE (MMP8)
Authors: VONROEDERN EG GRAMS F BRANDSTETTER H MORODER L
Citation: Eg. Vonroedern et al., DESIGN AND SYNTHESIS OF MALONIC ACID-BASED INHIBITORS OF HUMAN NEUTROPHIL COLLAGENASE (MMP8), Journal of medicinal chemistry, 41(3), 1998, pp. 339-345
BIS-SUBSTITUTED MALONIC-ACID HYDROXAMATE DERIVATIVES AS INHIBITORS OFHUMAN NEUTROPHIL COLLAGENASE (MMP8)
Authors: VONROEDERN EG BRANDSTETTER H ENGH RA BODE W GRAMS F MORODER L
Citation: Eg. Vonroedern et al., BIS-SUBSTITUTED MALONIC-ACID HYDROXAMATE DERIVATIVES AS INHIBITORS OFHUMAN NEUTROPHIL COLLAGENASE (MMP8), Journal of medicinal chemistry, 41(16), 1998, pp. 3041-3047
CHANGING RESIDUE-338 IN HUMAN FACTOR-IX FROM ARGININE TO ALANINE CAUSES AN INCREASE IN CATALYTIC ACTIVITY
Authors: CHANG JL JIN JP LOLLAR P BODE W BRANDSTETTER H HAMAGUCHI N STRAIGHT DL STAFFORD DW
Citation: Jl. Chang et al., CHANGING RESIDUE-338 IN HUMAN FACTOR-IX FROM ARGININE TO ALANINE CAUSES AN INCREASE IN CATALYTIC ACTIVITY, The Journal of biological chemistry, 273(20), 1998, pp. 12089-12094
CRYSTAL-STRUCTURES OF THE METHANE MONOOXYGENASE HYDROXYLASE FROM METHYLOCOCCUS-CAPSULATUS (BATH) - IMPLICATIONS FOR SUBSTRATE GATING AND COMPONENT INTERACTIONS
Authors: ROSENZWEIG AC BRANDSTETTER H WHITTINGTON DA NORDLUND P LIPPARD SJ FREDERICK CA
Citation: Ac. Rosenzweig et al., CRYSTAL-STRUCTURES OF THE METHANE MONOOXYGENASE HYDROXYLASE FROM METHYLOCOCCUS-CAPSULATUS (BATH) - IMPLICATIONS FOR SUBSTRATE GATING AND COMPONENT INTERACTIONS, Proteins, 29(2), 1997, pp. 141-152
COMPARATIVE-ANALYSIS OF HEMOSTATIC PROTEINASES - STRUCTURAL ASPECTS OF THROMBIN, FACTOR XA, FACTOR IXA AND PROTEIN-C
Authors: BODE W BRANDSTETTER H MATHER T STUBBS MT
Citation: W. Bode et al., COMPARATIVE-ANALYSIS OF HEMOSTATIC PROTEINASES - STRUCTURAL ASPECTS OF THROMBIN, FACTOR XA, FACTOR IXA AND PROTEIN-C, Thrombosis and haemostasis, 78(1), 1997, pp. 501-511
CONVERTING BLOOD-COAGULATION FACTOR IXA INTO FACTOR XA - DRAMATIC INCREASE IN AMIDOLYTIC ACTIVITY IDENTIFIES IMPORTANT ACTIVE-SITE DETERMINANTS
Authors: HOPFNER KP BRANDSTETTER H KARCHER A KOPETZKI E HUBER R ENGH RA BODE W
Citation: Kp. Hopfner et al., CONVERTING BLOOD-COAGULATION FACTOR IXA INTO FACTOR XA - DRAMATIC INCREASE IN AMIDOLYTIC ACTIVITY IDENTIFIES IMPORTANT ACTIVE-SITE DETERMINANTS, EMBO journal, 16(22), 1997, pp. 6626-6635
A SHORT SYNTHESIS OF THE FACTOR-XA INHIBITOR DX-9065A USING PALLADIUM-CATALYZED KEY STEPS
Authors: KEHR C NEIDLEIN R ENGH RA BRANDSTETTER H KUCZNIERZ R LEINERT H MARZENELL K STREIN K VONDERSAAL W
Citation: C. Kehr et al., A SHORT SYNTHESIS OF THE FACTOR-XA INHIBITOR DX-9065A USING PALLADIUM-CATALYZED KEY STEPS, Helvetica Chimica Acta, 80(3), 1997, pp. 892-896
ENZYME FLEXIBILITY, SOLVENT AND WEAK-INTERACTIONS CHARACTERIZE THROMBIN-LIGAND INTERACTIONS - IMPLICATIONS FOR DRUG DESIGN
Authors: ENGH RA BRANDSTETTER H SUCHER G EICHINGER A BAUMANN U BODE W HUBER R POLL T RUDOLPH R VONDERSAAL W
Citation: Ra. Engh et al., ENZYME FLEXIBILITY, SOLVENT AND WEAK-INTERACTIONS CHARACTERIZE THROMBIN-LIGAND INTERACTIONS - IMPLICATIONS FOR DRUG DESIGN, Structure, 4(11), 1996, pp. 1353-1362
X-RAY STRUCTURE OF ACTIVE SITE-INHIBITED CLOTTING FACTOR XA - IMPLICATIONS FOR DRUG DESIGN AND SUBSTRATE RECOGNITION
Authors: BRANDSTETTER H KUHNE A BODE W HUBER R VONDERSAAL W WIRTHENSOHN K ENGH RA
Citation: H. Brandstetter et al., X-RAY STRUCTURE OF ACTIVE SITE-INHIBITED CLOTTING FACTOR XA - IMPLICATIONS FOR DRUG DESIGN AND SUBSTRATE RECOGNITION, The Journal of biological chemistry, 271(47), 1996, pp. 29988-29992
THE X-RAY CRYSTAL-STRUCTURE OF THROMBIN IN COMPLEX WITH LFONYL-L-3-AMIDINO-PHENYLALANYL-4-METHYLPIPERIDIDE - THE BENEFICIAL EFFECT OF FILLING OUT AN EMPTY CAVITY
Authors: BERGNER A BAUER M BRANDSTETTER H STURZEBECHER J BODE W
Citation: A. Bergner et al., THE X-RAY CRYSTAL-STRUCTURE OF THROMBIN IN COMPLEX WITH LFONYL-L-3-AMIDINO-PHENYLALANYL-4-METHYLPIPERIDIDE - THE BENEFICIAL EFFECT OF FILLING OUT AN EMPTY CAVITY, Journal of enzyme inhibition, 9(1), 1995, pp. 101
IDENTIFICATION OF INTERLEUKIN-1 AND PLATELET-DERIVED GROWTH FACTOR-B AS MAJOR MITOGENS FOR THE SPINDLE CELLS OF KAPOSIS-SARCOMA - A COMBINED IN-VITRO AND IN-VIVO ANALYSIS
Authors: STURZL M BRANDSTETTER H ZIETZ C EISENBURG B RAIVICH G GEARING DP BROCKMEYER NH HOFSCHNEIDER PH
Citation: M. Sturzl et al., IDENTIFICATION OF INTERLEUKIN-1 AND PLATELET-DERIVED GROWTH FACTOR-B AS MAJOR MITOGENS FOR THE SPINDLE CELLS OF KAPOSIS-SARCOMA - A COMBINED IN-VITRO AND IN-VIVO ANALYSIS, Oncogene, 10(10), 1995, pp. 2007-2016
X-RAY STRUCTURE OF CLOTTING FACTOR IXA - ACTIVE-SITE AND MODULE STRUCTURE RELATED TO XASE ACTIVITY AND HEMOPHILIA-B
Authors: BRANDSTETTER H BAUER M HUBER R LOLLAR P BODE W
Citation: H. Brandstetter et al., X-RAY STRUCTURE OF CLOTTING FACTOR IXA - ACTIVE-SITE AND MODULE STRUCTURE RELATED TO XASE ACTIVITY AND HEMOPHILIA-B, Proceedings of the National Academy of Sciences of the United Statesof America, 92(21), 1995, pp. 9796-9800
KAPOSIS-SARCOMA (KS) AS A REACTIVE PROCESS - A NOVEL HYPOTHESIS FOR KS DEVELOPMENT
Authors: STURZL M OSKOUI KB BRANDSTETTER H ZIETZ C RAIVICH G GEARING D HOFSCHNEIDER PH
Citation: M. Sturzl et al., KAPOSIS-SARCOMA (KS) AS A REACTIVE PROCESS - A NOVEL HYPOTHESIS FOR KS DEVELOPMENT, AIDS research and human retroviruses, 10, 1994, pp. 190000051-190000051
EXPRESSION OF ADHESION MOLECULES, PLATELET-ACTIVATING-FACTOR, AND CHEMOKINES BY KAPOSIS-SARCOMA CELLS
Authors: SCIACCA FL STURZL M BUSSOLINO F SIRONI M BRANDSTETTER H ZIETZ C ZHOU D MATTEUCCI C PERI G SOZZANI S BENELLI R ARESE M ALBINI A COLOTTA F MANTOVANI A
Citation: Fl. Sciacca et al., EXPRESSION OF ADHESION MOLECULES, PLATELET-ACTIVATING-FACTOR, AND CHEMOKINES BY KAPOSIS-SARCOMA CELLS, The Journal of immunology, 153(10), 1994, pp. 4816-4825
PDGF AND ONCOSTATIN-M - IMPORTANT PATHOGENESIS FACTORS FOR KS INVIVO
Authors: BRANDSTETTER H ZIETZ C BROCKMEYER NH HOFSCHNEIDER PH STURZL M
Citation: H. Brandstetter et al., PDGF AND ONCOSTATIN-M - IMPORTANT PATHOGENESIS FACTORS FOR KS INVIVO, Journal of acquired immune deficiency syndromes, 6(6), 1993, pp. 689-689
THE THROMBIN STRUCTURE AS A TOOL FOR THE RATIONAL DESIGN OF ANTITHROMBOTICS
Authors: BAUER M BRANDSTETTER H STURZEBECHER J BODE W
Citation: M. Bauer et al., THE THROMBIN STRUCTURE AS A TOOL FOR THE RATIONAL DESIGN OF ANTITHROMBOTICS, Thrombosis and haemostasis, 69(6), 1993, pp. 666-666
CRYSTAL-STRUCTURES OF THROMBIN AS SIGNPOSTS TO ITS MULTIPLE FUNCTIONS
Authors: BODE W BRANDSTETTER H STUBBS M TURK D KARSHIKOV A BAUER M
Citation: W. Bode et al., CRYSTAL-STRUCTURES OF THROMBIN AS SIGNPOSTS TO ITS MULTIPLE FUNCTIONS, Thrombosis and haemostasis, 69(6), 1993, pp. 983-983
CRYSTALLOGRAPHIC DETERMINATION OF THROMBIN COMPLEXES WITH SMALL SYNTHETIC INHIBITORS AS A STARTING POINT FOR THE RECEPTOR-BASED DESIGN OF ANTITHROMBOTICS
Authors: BAUER M BRANDSTETTER H TURK D STURZEBECHER J BODE W
Citation: M. Bauer et al., CRYSTALLOGRAPHIC DETERMINATION OF THROMBIN COMPLEXES WITH SMALL SYNTHETIC INHIBITORS AS A STARTING POINT FOR THE RECEPTOR-BASED DESIGN OF ANTITHROMBOTICS, Seminars in thrombosis and hemostasis, 19(4), 1993, pp. 352-360
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