Authors:
ECKHARDT SG
BAKER SD
ECKARDT JR
BURKE TG
WARNER DL
KUHN JG
RODRIGUEZ G
FIELDS S
THURMAN A
SMITH L
ROTHENBERG ML
WHITE L
WISSEL P
KUNKA R
DEPEE S
LITTLEFIELD D
BURRIS HA
VONHOFF DD
ROWINSKY EK
Citation: Sg. Eckhardt et al., PHASE-I AND PHARMACOKINETIC STUDY OF GI147211, A WATER-SOLUBLE CAMPTOTHECIN ANALOG, ADMINISTERED FOR 5 CONSECUTIVE DAYS EVERY 3 WEEKS, Clinical cancer research, 4(3), 1998, pp. 595-604
Authors:
ECKHARDT SG
BAKER SD
ECKARDT JR
BURKE TG
WARNER DL
KUHN JG
RODRIGUEZ G
FIELDS S
THURMAN A
SMITH L
ROTHENBERG ML
WHITE L
WISSEL P
KUNKA R
DEPEE S
LITTLEFIELD D
BURRIS HA
VONHOFF DD
ROWINSKY EK
Citation: Sg. Eckhardt et al., PHASE-I AND PHARMACOKINETIC STUDY OF GI147211, A WATER-SOLUBLE CAMPTOTHECIN ANALOG, ADMINISTERED FOR 5 CONSECUTIVE DAYS EVERY 3 WEEKS, Clinical cancer research, 4(3), 1998, pp. 595-604
Authors:
MADDEN TD
DEMIR AS
BURKE TG
REDELMEIER TE
BALLY MB
Citation: Td. Madden et al., ENCAPSULATION OF TOPOTECAN IN LIPID-BASED CARRIER SYSTEMS - PHYSICAL FORMULATION, EVALUATION OF DRUG STABILITY AND PLASMA ELIMINATION IN A MURINE MODEL, AND COMPARISON OF ANTITUMOR EFFICACY AGAINST MURINE L1210 AND B16 TUMORS, Annals of oncology, 9, 1998, pp. 175-175
Authors:
YANG DZ
STRODE JT
SPIELMANN HP
WANG AHJ
DEMIR A
BURKE TG
Citation: Dz. Yang et al., DNA INTERACTIONS OF CLINICALLY RELEVANT CAMPTOTHECIN DRUGS STABILIZE THEIR ACTIVE LACTONE FORMS, Annals of oncology, 9, 1998, pp. 233-233
Citation: Tg. Burke et al., ACYL-CHAIN ORDER MARKEDLY IMPACTS ON THE PARTITIONING, STABILITY, ANDDYNAMICS OF CAMPTOTHECIN DRUGS IN LIPID BILAYERS, Biophysical journal, 74(2), 1998, pp. 202-202
Authors:
YANG DZ
STRODE JT
SPIELMANN HP
WANG AHJ
BURKE TG
Citation: Dz. Yang et al., DNA INTERACTIONS OF 2 CLINICAL CAMPTOTHECIN DRUGS STABILIZE THEIR ACTIVE LACTONE FORMS, Journal of the American Chemical Society, 120(12), 1998, pp. 2979-2980
Citation: Dl. Warner et Tg. Burke, SIMPLE AND VERSATILE HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHIC METHOD FOR THE SIMULTANEOUS QUANTITATION OF THE LACTONE AND CARBOXYLATE FORMS OF CAMPTOTHECIN ANTICANCER DRUGS, Journal of chromatography B. Biomedical sciences and applications, 691(1), 1997, pp. 161-171
Citation: Dl. Warner et Tg. Burke, COMPARISON OF FILTER AND TUNABLE FLUORESCENCE DETECTION FOR THE HPLC SIMULTANEOUS QUANTITATION OF LACTONE AND CARBOXYLATE FORMS OF TOPOTECAN IN PLASMA, Journal of liquid chromatography & related technologies, 20(10), 1997, pp. 1523-1537
Citation: A. Shenderova et al., STABILIZATION OF 10-HYDROXYCAMPTOTHECIN IN POLY(LACTIDE-CO-GLYCOLIDE)MICROSPHERE DELIVERY VEHICLES, Pharmaceutical research, 14(10), 1997, pp. 1406-1414
Authors:
BURKE TG
MALAK H
GRYCZYNSKI I
MI ZH
LAKOWICZ JR
Citation: Tg. Burke et al., CLINICAL SENSING OF THE ANTICANCER DRUG HYCAMTIN IN WHOLE-BLOOD AND PLASMA BY 2-PHOTON FLUORESCENCE, Biophysical journal, 72(2), 1997, pp. 380-380
Citation: Jd. Pilzer et al., DRUG ALLERGY ASSESSMENT AT A UNIVERSITY HOSPITAL AND CLINIC, American journal of health-system pharmacy, 53(24), 1996, pp. 2970-2975
Citation: Ed. Simmons et al., BIOMECHANICAL COMPARISON OF THE DEWAR AND INTERSPINAL CERVICAL-SPINE FIXATION TECHNIQUES, Spine (Philadelphia, Pa. 1976), 21(3), 1996, pp. 295-298
Citation: Tg. Burke et al., LIPID BILAYER PARTITIONING AND STABILITY OF SEVERAL NEW CAMPTOTHECIN-CLASS TOPOISOMERASE INHIBITORS, Biophysical journal, 70(2), 1996, pp. 212-212
Authors:
BURKE TG
MALAK H
GRYCZYNSKI I
MI ZH
LAKOWICZ JR
Citation: Tg. Burke et al., FLUORESCENCE DETECTION OF THE ANTICANCER DRUG TOPOTECAN IN PLASMA ANDWHOLE-BLOOD BY 2-PHOTON EXCITATION, Analytical biochemistry, 242(2), 1996, pp. 266-270
Authors:
BERGER I
SU L
SPITZNER JR
KANG C
BURKE TG
RICH A
Citation: I. Berger et al., MOLECULAR-STRUCTURE OF THE HALOGENATED ANTICANCER DRUG IODODOXORUBICIN COMPLEXED WITH D(TGTACA) AND D(CGATCG), Nucleic acids research, 23(21), 1995, pp. 4488-4494
Citation: Tg. Burke et al., THE IMPORTANT ROLE OF ALBUMIN IN DETERMINING THE RELATIVE HUMAN BLOODSTABILITIES OF THE CAMPTOTHECIN ANTICANCER DRUGS, Journal of pharmaceutical sciences, 84(4), 1995, pp. 518-519
Citation: Tg. Burke et al., THE IMPORTANT ROLE OF ALBUMIN IN DETERMINING THE RELATIVE HUMAN BLOODSTABILITIES OF THE CAMPTOTHECIN ANTICANCER DRUGS (VOL 84, PG 518, 1995), Journal of pharmaceutical sciences, 84(12), 1995, pp. 1492-1492
Citation: Zh. Mi et al., REDUCED ALBUMIN-BINDING PROMOTES THE STABILITY AND ACTIVITY OF TOPOTECAN IN HUMAN BLOOD, Biochemistry, 34(42), 1995, pp. 13722-13728
Citation: Tg. Burke et X. Gao, STABILIZATION OF TOPOTECAN IN LOW PH LIPOSOMES COMPOSED OF DISTEAROYLPHOSPHATIDYLCHOLINE, Journal of pharmaceutical sciences, 83(7), 1994, pp. 967-969
Citation: Tg. Burke et Zh. Mi, THE STRUCTURAL BASIS OF CAMPTOTHECIN INTERACTIONS WITH HUMAN SERUM-ALBUMIN - IMPACT ON DRUG STABILITY, Journal of medicinal chemistry, 37(1), 1994, pp. 40-46
Citation: Zh. Mi et Tg. Burke, MARKED INTERSPECIES VARIATIONS CONCERNING THE INTERACTIONS OF CAMPTOTHECIN WITH SERUM ALBUMINS - A FREQUENCY-DOMAIN FLUORESCENCE SPECTROSCOPIC STUDY, Biochemistry, 33(42), 1994, pp. 12540-12545
Citation: Zh. Mi et Tg. Burke, DIFFERENTIAL INTERACTIONS OF CAMPTOTHECIN LACTONE AND CARBOXYLATE FORMS WITH HUMAN BLOOD COMPONENTS, Biochemistry, 33(34), 1994, pp. 10325-10336
Citation: Tg. Burke et Z. Mi, ETHYL SUBSTITUTION AT THE 7-POSITION EXTENDS THE HALF-LIFE OF 10-HYDROXYCAMPTOTHECIN IN THE PRESENCE OF HUMAN SERUM-ALBUMIN, Journal of medicinal chemistry, 36(17), 1993, pp. 2580-2582