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Results: 1-5 |
Results: 5
Discovery and initial structure-activity relationships of trisubstituted ureas as thrombin receptor (PAR-1) antagonists
Authors: Barrow, JC Nantermet, PG Selnick, HG Glass, KL Ngo, PL Young, MB Pellicore, JM Breslin, MJ Hutchinson, JH Freidinger, RM Condra, C Karczewski, J Bednar, RA Gaul, SL Stern, A Gould, R Connolly, TM
Citation: Jc. Barrow et al., Discovery and initial structure-activity relationships of trisubstituted ureas as thrombin receptor (PAR-1) antagonists, BIOORG MED, 11(20), 2001, pp. 2691-2696
Nonpeptide GPIIB/IIIA receptor antagonists. Part 21: C-6 flexibility and amide bond orientation are important factors in determining the affinity of compounds for activated or resting platelet receptors
Authors: Egbertson, MS Bednar, B Askew, BC Bednar, RA Brashear, K Breslin, MJ Duggan, ME Fisher, TE Halczenko, W Hutchinson, JH Ihle, N Prugh, JD Wai, JS Gould, RJ Hartman, GD
Citation: Ms. Egbertson et al., Nonpeptide GPIIB/IIIA receptor antagonists. Part 21: C-6 flexibility and amide bond orientation are important factors in determining the affinity of compounds for activated or resting platelet receptors, BIOORG MED, 10(17), 2000, pp. 1943-1948
Non-peptide GPIIb/IIIa inhibitors. 20. Centrally constrained thienothiophene alpha-sulfonamides are potent, long acting in vivo inhibitors of platelet aggregation. (vol 42, pg 2409, 1999)
Authors: Egbertson, MS Cook, JJ Bednar, B Prugh, JD Bednar, RA Gaul, SL Gould, RJ Hartman, GD Homnick, CF Holahan, MA Libby, LA Lynch, JJ Lynch, RJ Sitko, GR Stranieri, MT Vasallo, LM
Citation: Ms. Egbertson et al., Non-peptide GPIIb/IIIa inhibitors. 20. Centrally constrained thienothiophene alpha-sulfonamides are potent, long acting in vivo inhibitors of platelet aggregation. (vol 42, pg 2409, 1999), J MED CHEM, 42(19), 1999, pp. 4014-4014
Non-peptide GPIIb IIIa inhibitors. 20. Centrally constrained thienothiophene alpha-sulfonamides are potent, long acting in vivo inhibitors of platelet aggregation
Authors: Egbertson, MS Cook, JJ Bednar, B Prugh, JD Bednar, RA Gaul, SL Gould, RJ Hartman, GD Homnick, CF Holahan, MA Libby, LA Lynch, JJ Lynch, RJ Sitko, GR Stranieri, MT Vassallo, LM
Citation: Ms. Egbertson et al., Non-peptide GPIIb IIIa inhibitors. 20. Centrally constrained thienothiophene alpha-sulfonamides are potent, long acting in vivo inhibitors of platelet aggregation, J MED CHEM, 42(13), 1999, pp. 2409-2421
Fibrinogen receptor antagonist-induced thrombocytopenia in chimpanzee and rhesus monkey associated with preexisting drug-dependent antibodies to platelet glycoprotein IIb IIIa
Authors: Bednar, B Cook, JJ Holahan, MA Cunningham, ME Jumes, PA Bednar, RA Hartman, GD Gould, RJ
Citation: B. Bednar et al., Fibrinogen receptor antagonist-induced thrombocytopenia in chimpanzee and rhesus monkey associated with preexisting drug-dependent antibodies to platelet glycoprotein IIb IIIa, BLOOD, 94(2), 1999, pp. 587-599
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