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Results: 1-25/39
Authors:
Grillo, MP
Benet, LZ
Citation: Mp. Grillo et Lz. Benet, Interaction of gamma-glutamyltranspeptidase with clofibryl-S-acyl-glutathione in vitro and in vivo in rat, CHEM RES T, 14(8), 2001, pp. 1033-1040
Authors:
Cummins, CL
Mangravite, LM
Benet, LZ
Citation: Cl. Cummins et al., Characterizing the expression of CYP3A4 and efflux transporters (P-gp, MRP1, and MRP2) in CYP3A4-transfected Caco-2 cells after induction with sodiumbutyrate and the phorbol ester 12-O-tetradecanoylphorbol-13-acetate, PHARM RES, 18(8), 2001, pp. 1102-1109
Authors:
Parasrampuria, DA
Lantz, MV
Benet, LZ
Citation: Da. Parasrampuria et al., A human lymphocyte based ex vivo assay to study the effect of drugs on P-glycoprotein (P-gp) function, PHARM RES, 18(1), 2001, pp. 39-44
Authors:
Zhang, YC
Benet, LZ
Citation: Yc. Zhang et Lz. Benet, The gut as a barrier to drug absorption - Combined role of cytochrome P4503A and P-glycoprotein, CLIN PHARMA, 40(3), 2001, pp. 159-168
Authors:
Benet, LZ
Cummins, CL
Citation: Lz. Benet et Cl. Cummins, The drug efflux-metabolism alliance: biochemical aspects, ADV DRUG DE, 50, 2001, pp. S3-S11
Authors:
Wacher, VJ
Salphati, L
Benet, LZ
Citation: Vj. Wacher et al., Active secretion and enterocytic drug metabolism barriers to drug absorption, ADV DRUG DE, 46(1-3), 2001, pp. 89-102
Authors:
Grillo, MP
Chiellini, G
Tonelli, M
Benet, LZ
Citation: Mp. Grillo et al., Effect of alpha-fluorination of valproic acid on valproyl-S-acyl-CoA formation in vivo in rats, DRUG META D, 29(9), 2001, pp. 1210-1215
Authors:
Jacobsen, W
Serkova, N
Hausen, B
Morris, RE
Benet, LZ
Christians, U
Citation: W. Jacobsen et al., Comparison of the in vitro metabolism of the macrolide immunosuppressants sirolimus and RAD, TRANSPLAN P, 33(1-2), 2001, pp. 514-515
Authors:
Kuhn, B
Jacobsen, W
Christians, U
Benet, LZ
Kollman, PA
Citation: B. Kuhn et al., Metabolism of sirolimus and its derivative everolimus by cytochrome P450 3A4: Insights from docking, molecular dynamics, and quantum chemical calculations, J MED CHEM, 44(12), 2001, pp. 2027-2034
Authors:
Tsunoda, SM
Harris, RZ
Christians, U
Velez, RL
Freeman, RB
Benet, LZ
Warshaw, A
Citation: Sm. Tsunoda et al., Red wine decreases cyclosporine bioavailability, CLIN PHARM, 70(5), 2001, pp. 462-467
Authors:
Mancinelli, LM
Frassetto, L
Floren, LC
Dressler, D
Carrier, S
Bekersky, I
Benet, LZ
Christians, U
Citation: Lm. Mancinelli et al., The pharmacokinetics and metabolic disposition of tacrolimus: A comparisonacross ethnic groups, CLIN PHARM, 69(1), 2001, pp. 24-31
Authors:
Serkova, N
Jacobsen, W
Niemann, CU
Litt, L
Benet, LZ
Leibfritz, D
Christians, U
Citation: N. Serkova et al., Sirolimus, but not the structurally related RAD (everolimus), enhances thenegative effects of cyclosporine on mitochondrial metabolism in the rat brain, BR J PHARM, 133(6), 2001, pp. 875-885
Authors:
Christians, U
Jacobsen, W
Serkova, N
Benet, LZ
Vidal, C
Sewing, KF
Manns, MP
Kirchner, GI
Citation: U. Christians et al., Automated, fast and sensitive quantification of drugs in blood by liquid chromatography-mass spectrometry with on-line extraction: immunosuppressants, J CHROMAT B, 748(1), 2000, pp. 41-53
Authors:
Benet, LZ
Citation: Lz. Benet, Permeability, metabolism, transporters and systemic exposure, EUR J DRUG, 25(1), 2000, pp. 68-68
Authors:
Boni, JP
Korth-Bradley, JM
Richards, LS
Chiang, ST
Hicks, DR
Benet, LZ
Citation: Jp. Boni et al., Chiral bioequivalence - Effect of absorption rate on racemic etodolac, CLIN PHARMA, 39(6), 2000, pp. 459-469
Authors:
Christians, U
First, MR
Benet, LZ
Citation: U. Christians et al., Recommendations for bioequivalence testing of cyclosporine generics revisited, THER DRUG M, 22(3), 2000, pp. 330-345
Authors:
Jacobsen, W
Christians, U
Benet, LZ
Citation: W. Jacobsen et al., In vitro evaluation of the disposition of a novel cysteine protease inhibitor, DRUG META D, 28(11), 2000, pp. 1343-1351
Authors:
Jacobsen, W
Kuhn, B
Soldner, A
Kirchner, G
Sewing, KF
Kollman, PA
Benet, LZ
Christians, U
Citation: W. Jacobsen et al., Lactonization is the critical first step in the disposition of the 3-hydroxy-3-methylglutaryl-CoA reductase inhibitor atorvastatin, DRUG META D, 28(11), 2000, pp. 1369-1378
Authors:
Hausen, B
Ikonen, T
Briffa, N
Berry, GJ
Christians, U
Robbins, RC
Hook, L
Serkova, N
Benet, LZ
Schuler, W
Morris, RE
Citation: B. Hausen et al., Combined immunosuppression with cyclosporine (Neoral) and SDZ RAD in non-human primate lung transplantation: Systematic pharmacokinetic-based trials to improve efficacy and tolerability, TRANSPLANT, 69(1), 2000, pp. 76-86
Authors:
Serkova, N
Hausen, B
Berry, GJ
Jacobsen, W
Benet, LZ
Morris, RE
Christians, U
Citation: N. Serkova et al., Tissue distribution and clinical monitoring of the novel macrolide immunosuppressant SDZ-RAD and its metabolites in monkey lung transplant recipients: Interaction with cyclosporine, J PHARM EXP, 294(1), 2000, pp. 323-332
Authors:
Soldner, A
Benet, LZ
Mutschler, E
Christians, U
Citation: A. Soldner et al., Active transport of the angiotensin-II antagonist losartan and its main metabolite EXP 3174 across MDCK-MDR1 and Caco-2 cell monolayers, BR J PHARM, 129(6), 2000, pp. 1235-1243
Authors:
Serkova, N
Litt, L
Leibfritz, D
Hausen, B
Morris, RE
James, TL
Benet, LZ
Christians, U
Citation: N. Serkova et al., The novel immunosuppressant SDZ-RAD protects rat brain slices from cyclosporine-induced reduction of high-energy phosphates, BR J PHARM, 129(3), 2000, pp. 485-492
Authors:
Soldner, A
Christians, U
Susanto, M
Wacher, VJ
Silverman, JA
Benet, LZ
Citation: A. Soldner et al., Grapefruit juice activates P-glycoprotein-mediated drug transport, PHARM RES, 16(4), 1999, pp. 478-485
Authors:
Flanagan, SD
Benet, LZ
Citation: Sd. Flanagan et Lz. Benet, Net secretion of furosemide is subject to indomethacin inhibition, as observed in Caco-2 monolayers and excised rat jejunum, PHARM RES, 16(2), 1999, pp. 221-224
Authors:
Mizuma, T
McDonagh, AF
Lin, ET
Benet, LZ
Citation: T. Mizuma et al., Photoinduced covalent binding of frusemide and frusemide glucuronide to human serum albumin, BR J CL PH, 48(1), 1999, pp. 79-87