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Results: 1-21 |
Results: 21
Synthesis of anticonvulsive AMPA antagonists: 4-oxo-10-substituted-imidazo[1,2-a]indeno[1,2-e]pyrazin-2-carboxylic acid derivatives
Authors: Stutzmann, JM Bohme, GA Boireau, A Damour, D Debono, MW Genevois-Borella, A Jimonet, P Pratt, J Randle, JCR Ribeill, Y Vuilhorgne, M Mignani, S
Citation: Jm. Stutzmann et al., Synthesis of anticonvulsive AMPA antagonists: 4-oxo-10-substituted-imidazo[1,2-a]indeno[1,2-e]pyrazin-2-carboxylic acid derivatives, BIOORG MED, 11(9), 2001, pp. 1205-1210
Bioisosteres of 9-carboxymethyl-4-oxo-imidazo[1,2-a]indeno-[1,2-e]pyrazin-2-carboxylic acid derivatives. Progress towards selective, potent in vivo AMPA antagonists with longer durations of action
Authors: Jimonet, P Bohme, GA Bouquerel, J Boireau, A Damour, D Debono, MW Genevois-Borella, A Hardy, JC Hubert, P Manfre, F Nemecek, P Pratt, J Randle, JCR Ribeill, Y Stutzmann, JM Vuilhorgne, M Mignani, S
Citation: P. Jimonet et al., Bioisosteres of 9-carboxymethyl-4-oxo-imidazo[1,2-a]indeno-[1,2-e]pyrazin-2-carboxylic acid derivatives. Progress towards selective, potent in vivo AMPA antagonists with longer durations of action, BIOORG MED, 11(2), 2001, pp. 127-132
Riluzole reduces hyperactivity of subthalamic neurons induced by unilateral 6-OHDA lesion in the rat brain
Authors: Hassani, OK Mouroux, M Bohme, GA Stutzmann, JM Feger, J
Citation: Ok. Hassani et al., Riluzole reduces hyperactivity of subthalamic neurons induced by unilateral 6-OHDA lesion in the rat brain, MOVEMENT D, 16(6), 2001, pp. 1110-1114
Antisense oligodeoxynucleotide to inducible nitric oxide synthase protectsagainst transient focal cerebral ischemia-induced brain injury
Authors: Parmentier-Batteur, S Bohme, GA Lerouet, D Li, ZD Beray, V Margaill, I Plotkine, M
Citation: S. Parmentier-batteur et al., Antisense oligodeoxynucleotide to inducible nitric oxide synthase protectsagainst transient focal cerebral ischemia-induced brain injury, J CEREBR B, 21(1), 2001, pp. 15-21
Cannabinoid CB1 receptor knockout mice fail to self-administer morphine but not other drugs of abuse
Authors: Cossu, G Ledent, C Fattore, L Imperato, A Bohme, GA Parmentier, M Fratta, W
Citation: G. Cossu et al., Cannabinoid CB1 receptor knockout mice fail to self-administer morphine but not other drugs of abuse, BEH BRA RES, 118(1), 2001, pp. 61-65
RPR 119990, a novel alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid antagonist: Synthesis, pharmacological properties, and activity in an animal model of amyotrophic lateral sclerosis
Authors: Canton, T Bohme, GA Boireau, A Bordier, F Mignani, S Jimonet, P Jahn, G Alavijeh, M Stygall, J Roberts, S Brealey, C Vuilhorgne, M Debono, MW Le Guern, S Laville, M Briet, D Roux, M Stutzmann, JM Pratt, J
Citation: T. Canton et al., RPR 119990, a novel alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid antagonist: Synthesis, pharmacological properties, and activity in an animal model of amyotrophic lateral sclerosis, J PHARM EXP, 299(1), 2001, pp. 314-322
8-Methylureido-10-amino-10-methyl-imidazo[1,2-a]indeno[1,2-e] pyrazine-4-ones: Highly in vivo potent and selective AMPA receptor antagonists
Authors: Jimonet, P Cheve, M Bohme, GA Boireau, A Damour, D Debono, MW Genevois-Borella, A Imperato, A Pratt, J Randle, JCR Ribeill, Y Stutzmann, JM Vuilhorgne, M Mignani, S
Citation: P. Jimonet et al., 8-Methylureido-10-amino-10-methyl-imidazo[1,2-a]indeno[1,2-e] pyrazine-4-ones: Highly in vivo potent and selective AMPA receptor antagonists, BIO MED CH, 8(8), 2000, pp. 2211-2217
8-Methylureido-4,5-dihyro-4-oxo-10H-imidazo[1,2-a]indeno[1,2-e]pyrazines: Highly potent in vivo AMPA antagonists
Authors: Mignani, S Bohme, GA Boireau, A Cheve, M Damour, D Debono, MW Genevois-Borella, A Imperato, A Jimonet, P Pratt, J Randle, JCR Ribeill, Y Vuilhorgne, M Stutzmann, JM
Citation: S. Mignani et al., 8-Methylureido-4,5-dihyro-4-oxo-10H-imidazo[1,2-a]indeno[1,2-e]pyrazines: Highly potent in vivo AMPA antagonists, BIOORG MED, 10(6), 2000, pp. 591-596
Synthesis and potent anticonvulsant activities of 4-oxo-imidazo[1,2-a]indeno[1,2-e]pyrazin-8-and-9-carboxylic (acetic) acid AMPA antagonists
Authors: Pratt, J Jimonet, P Bohme, GA Boireau, A Damour, D Debono, MW Genevois-Borella, A Randle, JCR Ribeill, Y Stutzmann, JM Vuilhorgne, M Mignani, S
Citation: J. Pratt et al., Synthesis and potent anticonvulsant activities of 4-oxo-imidazo[1,2-a]indeno[1,2-e]pyrazin-8-and-9-carboxylic (acetic) acid AMPA antagonists, BIOORG MED, 10(24), 2000, pp. 2749-2754
4,10-dihydro-4-oxo-4H-imidazo[1,2-a]indeno[1,2-e]pyrazin-2-carboxylic acidderivatives: Highly potent and selective AMPA receptors antagonists with in vivo activity
Authors: Stutzmann, JM Bohme, GA Boireau, A Damour, D Debono, MW Genevois-Borella, A Imperato, A Jimonet, P Pratt, J Randle, JCR Ribeill, Y Vuilhorgne, M Mignani, S
Citation: Jm. Stutzmann et al., 4,10-dihydro-4-oxo-4H-imidazo[1,2-a]indeno[1,2-e]pyrazin-2-carboxylic acidderivatives: Highly potent and selective AMPA receptors antagonists with in vivo activity, BIOORG MED, 10(10), 2000, pp. 1133-1137
Enhanced long-term potentiation in mice lacking cannabinoid CB1 receptors
Authors: Bohme, GA Laville, M Ledent, C Parmentier, M Imperato, A
Citation: Ga. Bohme et al., Enhanced long-term potentiation in mice lacking cannabinoid CB1 receptors, NEUROSCIENC, 95(1), 2000, pp. 5-7
Riluzole prolongs survival and delays muscle strength deterioration in mice with progressive motor neuronopathy (pmn)
Authors: Kennel, P Revah, F Bohme, GA Bejuit, R Gallix, P Stutzmann, JM Imperato, A Pratt, J
Citation: P. Kennel et al., Riluzole prolongs survival and delays muscle strength deterioration in mice with progressive motor neuronopathy (pmn), J NEUR SCI, 180(1-2), 2000, pp. 55-61
Cloning of rat parkin cDNA and distribution of parkin in rat brain
Authors: Gu, WJ Abbas, N Lagunes, MZ Parent, A Pradier, L Bohme, GA Agid, Y Hirsch, EC Raisman-Vozari, R Brice, A
Citation: Wj. Gu et al., Cloning of rat parkin cDNA and distribution of parkin in rat brain, J NEUROCHEM, 74(4), 2000, pp. 1773-1776
Indeno[1,2-b]pyrazin-2,3-diones: A new class of antagonists at the glycinesite of the NMDA receptor with potent in vivo activity
Authors: Jimonet, P Ribeill, Y Bohme, GA Boireau, A Cheve, M Damour, D Doble, A Genevois-Borella, A Herman, F Imperato, A Le Guern, S Manfre, F Pratt, J Randle, JCR Stutzmann, JM Mignani, S
Citation: P. Jimonet et al., Indeno[1,2-b]pyrazin-2,3-diones: A new class of antagonists at the glycinesite of the NMDA receptor with potent in vivo activity, J MED CHEM, 43(12), 2000, pp. 2371-2381
A wide variety of mutations in the parkin gene are responsible for autosomal recessive parkinsonism in Europe
Authors: Abbas, N Lucking, CB Ricard, S Durr, A Bonifati, V De Michele, G Bouley, S Vaughan, JR Gasser, T Marconi, R Broussolle, E Brefel-Courbon, C Harhangi, BS Oostra, AB Fabrizio, E Bohme, GA Pradier, L Wood, NW Filla, A Meco, G Denefle, P Agid, Y Brice, A
Citation: N. Abbas et al., A wide variety of mutations in the parkin gene are responsible for autosomal recessive parkinsonism in Europe, HUM MOL GEN, 8(4), 1999, pp. 567-574
The effect of riluzole and mannitol on cerebral oedema after cryogenic injury in the mouse
Authors: Pratt, J Archambaud, C Bohme, GA Roux, M Rataud, J Imperato, A Stutzmann, JM
Citation: J. Pratt et al., The effect of riluzole and mannitol on cerebral oedema after cryogenic injury in the mouse, NEUROSCI L, 272(3), 1999, pp. 143-146
Synthesis and pharmacological properties of 5H,10H-imidazo[1,2-a]indeno[1,2-e]pyrazine-4-one, a new competitive AMPA/KA receptor antagonist
Authors: Mignani, S Aloup, JC Barreau, M Blanchard, JC Bohme, GA Boireau, A Damour, D Debono, MW Dubroeucq, MC Genevois-Borella, A Imperato, A Jimonet, P Pratt, J Randle, JCR Reibaud, M Ribeill, Y Stutzmann, JM
Citation: S. Mignani et al., Synthesis and pharmacological properties of 5H,10H-imidazo[1,2-a]indeno[1,2-e]pyrazine-4-one, a new competitive AMPA/KA receptor antagonist, DRUG DEV R, 48(3), 1999, pp. 121-129
Unresponsiveness to cannabinoids and reduced addictive effects of opiates in CB1 receptor knockout mice
Authors: Ledent, C Valverde, O Cossu, C Petitet, F Aubert, LF Beslot, F Bohme, GA Imperato, A Pedrazzini, T Roques, BP Vassart, G Fratta, W Parmentier, M
Citation: C. Ledent et al., Unresponsiveness to cannabinoids and reduced addictive effects of opiates in CB1 receptor knockout mice, SCIENCE, 283(5400), 1999, pp. 401-404
Lack of morphine-induced dopamine release in the nucleus accumbens of cannabinoid CB1 receptor knockout mice
Authors: Mascia, MS Obinu, MC Ledent, C Parmentier, M Bohme, GA Imperato, A Fratta, W
Citation: Ms. Mascia et al., Lack of morphine-induced dopamine release in the nucleus accumbens of cannabinoid CB1 receptor knockout mice, EUR J PHARM, 383(3), 1999, pp. R1-R2
Enhancement of memory in cannabinoid CB1 receptor knock-out mice
Authors: Reibaud, M Obinu, MC Ledent, C Parmentier, M Bohme, GA Imperato, A
Citation: M. Reibaud et al., Enhancement of memory in cannabinoid CB1 receptor knock-out mice, EUR J PHARM, 379(1), 1999, pp. R1-R2
Selective inhibition of inducible nitric oxide synthase prevents ischaemicbrain injury
Authors: Parmentier, S Bohme, GA Lerouet, D Damour, D Stutzmann, JM Margaill, I Plotkine, M
Citation: S. Parmentier et al., Selective inhibition of inducible nitric oxide synthase prevents ischaemicbrain injury, BR J PHARM, 127(2), 1999, pp. 546-552
Risultati: 1-21 |