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Results: 1-25/37
Authors:
Gao, J
Winslow, SL
Vander Velde, D
Aube, J
Borchardt, RT
Citation: J. Gao et al., Transport characteristics of peptides and peptidomimetics: II. Hydroxyethylamine bioisostere-containing peptidomimetics as substrates for the oligopeptide transporter and P-glycoprotein in the intestinal mucosa, J PEPT RES, 57(5), 2001, pp. 361-373
Authors:
Gao, J
Sudoh, M
Aube, J
Borchardt, RT
Citation: J. Gao et al., Transport characteristics of peptides and peptidomimetics: I. N-methylatedpeptides as substrates for the oligopeptide transporter and P-glycoproteinin the intestinal mucosa, J PEPT RES, 57(4), 2001, pp. 316-329
Authors:
Borchardt, RT
Citation: Rt. Borchardt, Integrating drug discovery and development, SCIENTIST, 15(5), 2001, pp. 43-43
Authors:
Gao, JN
Murase, O
Schowen, RL
Aube, J
Borchardt, RT
Citation: Jn. Gao et al., A functional assay for quantitation of the apparent affinities of ligands of P-glycoprotein in Caco-2 cells, PHARM RES, 18(2), 2001, pp. 171-176
Authors:
Wang, W
Dentler, WL
Borchardt, RT
Citation: W. Wang et al., VEGF increases BMEC monolayer permeability by affecting occludin expression and tight junction assembly, AM J P-HEAR, 280(1), 2001, pp. H434-H440
Authors:
Borchardt, RT
Citation: Rt. Borchardt, Untitled, J PHARM SCI, 90(8), 2001, pp. 967-968
Authors:
Song, Y
Schowen, RL
Borchardt, RT
Topp, EM
Citation: Y. Song et al., Formaldehyde production by Tris buffer in peptide formulations at elevatedtemperature, J PHARM SCI, 90(8), 2001, pp. 1198-1203
Authors:
Song, Y
Schowen, RL
Borchardt, RT
Topp, EM
Citation: Y. Song et al., Effect of 'pH' on the rate of asparagine deamidation in polymeric formulations: 'pH'-rate profile, J PHARM SCI, 90(2), 2001, pp. 141-156
Authors:
Li, R
D'Souza, AJ
Laird, BB
Schowen, RL
Borchardt, RT
Topp, EM
Citation: R. Li et al., Effects of solution polarity and viscosity on peptide deamidation, J PEPT RES, 56(5), 2000, pp. 326-334
Authors:
Xie, M
Aube, J
Borchardt, RT
Morton, M
Topp, EM
Vander Velde, D
Schowen, RL
Citation: M. Xie et al., Reactivity toward deamidation of asparagine residues in beta-turn structures, J PEPT RES, 56(3), 2000, pp. 165-171
Authors:
Lai, MC
Schowen, RL
Borchardt, RT
Topp, EM
Citation: Mc. Lai et al., Deamidation of a model hexapeptide in poly(vinyl alcohol) hydrogels and xerogels, J PEPT RES, 55(2), 2000, pp. 93-101
Authors:
Wang, W
Borchardt, RT
Wang, B
Citation: W. Wang et al., Orally active peptidomimetic RGD analogs that are glycoprotein IIb/IIIa antagonists, CURR MED CH, 7(4), 2000, pp. 437-453
Authors:
Khossravi, M
Borchardt, RT
Citation: M. Khossravi et Rt. Borchardt, Chemical pathways of peptide degradation. X: Effect of metal-catalyzed oxidation on the solution structure of a histidine-containing peptide fragmentof human relaxin, PHARM RES, 17(7), 2000, pp. 851-858
Authors:
Wang, W
Camenisch, G
Sane, DC
Zhang, HJ
Hugger, E
Wheeler, GL
Borchardt, RT
Wang, BH
Citation: W. Wang et al., A coumarin-based prodrug strategy to improve the oral absorption of RGD peptidomimetics, J CONTR REL, 65(1-2), 2000, pp. 245-251
Authors:
Goolcharran, C
Stauffer, LL
Cleland, JL
Borchardt, RT
Citation: C. Goolcharran et al., The effects of a histidine residue on the c-terminal side of an asparaginyl residue on the rate of deamidation using model pentapeptides, J PHARM SCI, 89(6), 2000, pp. 818-825
Authors:
Wnuk, SF
Valdez, CA
Khan, J
Moutinho, P
Robins, MJ
Yang, XD
Borchardt, RT
Balzarini, J
De Clercq, E
Citation: Sf. Wnuk et al., Doubly homologated dihalovinyl and acetylene analogues of adenosine: Synthesis, interaction with S-adenosyl-L-homocysteine hydrolase, and antiviral and cytostatic effects, J MED CHEM, 43(6), 2000, pp. 1180-1186
Authors:
Shan, DX
Zheng, AL
Ballard, CE
Wang, W
Borchardt, RT
Wang, BH
Citation: Dx. Shan et al., A facilitated cyclic ether formation and its potential application in solid-phase peptide and organic synthesis, CHEM PHARM, 48(2), 2000, pp. 238-244
Authors:
Yang, XD
Yin, D
Wnuk, SF
Robins, MJ
Borchardt, RT
Citation: Xd. Yang et al., Mechanisms of inactivation of human S-adenosylhomocysteine hydrolase by 5 ',5 ',6 ',6 '-tetradehydro-6 '-deoxy-6 '-halohomoadenosines, BIOCHEM, 39(49), 2000, pp. 15234-15241
Authors:
Yin, D
Yang, XD
Hu, YB
Kuczera, K
Schowen, RL
Borchardt, RT
Squier, TC
Citation: D. Yin et al., Substrate binding stabilizes S-adenosylhomocysteine hydrolase in a closed conformation, BIOCHEM, 39(32), 2000, pp. 9811-9818
Authors:
Khossravi, M
Shire, SJ
Borchardt, RT
Citation: M. Khossravi et al., Evidence for the involvement of histidine A(12) in the aggregation and precipitation of human relaxin induced by metal-catalyzed oxidation, BIOCHEM, 39(19), 2000, pp. 5876-5885
Authors:
Yang, X
Borchardt, RT
Citation: X. Yang et Rt. Borchardt, Overexpression, purification, and characterization of S-adenosylhomocysteine hydrolase from Leishmania donovani, ARCH BIOCH, 383(2), 2000, pp. 272-280
Authors:
Ho, NFH
Raub, TJ
Burton, PS
Bausuhn, CL
Adson, A
Audus, KL
Borchardt, RT
Citation: Nfh. Ho et al., Quantitative approaches to delineate passive transport mechanisms in cell culture monolayers, DRUG PHARM, 102, 2000, pp. 219-316
Authors:
Borchardt, RT
Citation: Rt. Borchardt, Untitled, J PEPT RES, 53(4), 1999, pp. 354-354
Authors:
Wang, B
Nimkar, K
Wang, W
Zhang, H
Shan, D
Gudmundsson, O
Gangwar, S
Siahaan, T
Borchardt, RT
Citation: B. Wang et al., Synthesis and evaluation of the physicochemical properties of esterase-sensitive cyclic prodrugs of opioid peptides using coumarinic acid and phenylpropionic acid linkers, J PEPT RES, 53(4), 1999, pp. 370-382
Authors:
Gudmundsson, OS
Jois, SDS
Vander Velde, DG
Siahaan, TJ
Wang, B
Borchardt, RT
Citation: Os. Gudmundsson et al., The effect of conformation on the membrane permeation of coumarinic acid- and phenylpropionic acid-based cyclic prodrugs of opioid peptides, J PEPT RES, 53(4), 1999, pp. 383-392