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Results: 1-24 |
Results: 24
Co-expression of multiple transgenes in mouse CNS: a comparison of strategies
Authors: Jankowsky, JL Slunt, HH Ratovitski, T Jenkins, NA Copeland, NG Borchelt, DR
Citation: Jl. Jankowsky et al., Co-expression of multiple transgenes in mouse CNS: a comparison of strategies, BIOMOL ENG, 17(6), 2001, pp. 157-165
BACE1 is the major beta-secretase for generation of A beta peptides by neurons
Authors: Cai, HB Wang, YS McCarthy, D Wen, HJ Borchelt, DR Price, DL Wong, PC
Citation: Hb. Cai et al., BACE1 is the major beta-secretase for generation of A beta peptides by neurons, NAT NEUROSC, 4(3), 2001, pp. 233-234
Distinct behavioral and neuropathological abnormalities in transgenic mouse models of HD and DRPLA
Authors: Schilling, G Jinnah, HA Gonzales, V Coonfield, ML Kim, Y Wood, JD Price, DL Li, XJ Jenkins, N Copeland, N Moran, T Ross, CA Borchelt, DR
Citation: G. Schilling et al., Distinct behavioral and neuropathological abnormalities in transgenic mouse models of HD and DRPLA, NEUROBIOL D, 8(3), 2001, pp. 405-418
Creatine increases survival and delays motor symptoms in a transgenic animal model of Huntington's disease
Authors: Andreassen, OA Dedeoglu, A Ferrante, RJ Jenkins, BG Ferrante, KL Thomas, M Friedlich, A Browne, SE Schilling, G Borchelt, DR Hersch, SM Ross, CA Beal, MF
Citation: Oa. Andreassen et al., Creatine increases survival and delays motor symptoms in a transgenic animal model of Huntington's disease, NEUROBIOL D, 8(3), 2001, pp. 479-491
Hyper-expression of human apolipoprotein E4 in astroglia and neurons does not enhance amyloid deposition in transgenic mice
Authors: Lesuisse, C Xu, GL Anderson, J Wong, M Jankowsky, J Holtz, G Gonzalez, V Wong, PCY Price, DL Tang, F Wagner, S Borchelt, DR
Citation: C. Lesuisse et al., Hyper-expression of human apolipoprotein E4 in astroglia and neurons does not enhance amyloid deposition in transgenic mice, HUM MOL GEN, 10(22), 2001, pp. 2525-2537
Genetically engineered models relevant to neurodegenerative disorders - Their value for understanding disease mechanisms and designing/testing experimental therapeutics
Authors: Wong, PC Cai, HB Borchelt, DR Price, DL
Citation: Pc. Wong et al., Genetically engineered models relevant to neurodegenerative disorders - Their value for understanding disease mechanisms and designing/testing experimental therapeutics, J MOL NEURO, 17(2), 2001, pp. 233-257
Dichloroacetate exerts therapeutic effects in transgenic mouse models of Huntington's disease
Authors: Andreassen, OA Ferrante, RJ Huang, HM Dedeoglu, A Park, L Ferrante, KL Kwon, J Borchelt, DR Ross, CA Gibson, GE Beal, MF
Citation: Oa. Andreassen et al., Dichloroacetate exerts therapeutic effects in transgenic mouse models of Huntington's disease, ANN NEUROL, 50(1), 2001, pp. 112-117
Coenzyme Q10 and remacemide hydrochloride ameliorate motor deficits in a Huntington's disease transgenic mouse model
Authors: Schilling, G Coonfield, ML Ross, CA Borchelt, DR
Citation: G. Schilling et al., Coenzyme Q10 and remacemide hydrochloride ameliorate motor deficits in a Huntington's disease transgenic mouse model, NEUROSCI L, 315(3), 2001, pp. 149-153
Enhanced synaptic potentiation in transgenic mice expressing presenilin 1 familial Alzheimer's disease mutation is normalized with a benzodiazepine
Authors: Zaman, SH Parent, A Laskey, A Lee, MK Borchelt, DR Sisodia, SS Malinow, R
Citation: Sh. Zaman et al., Enhanced synaptic potentiation in transgenic mice expressing presenilin 1 familial Alzheimer's disease mutation is normalized with a benzodiazepine, NEUROBIOL D, 7(1), 2000, pp. 54-63
Decreased expression of striatal signaling genes in a mouse model of Huntington's disease
Authors: Luthi-Carter, R Strand, A Peters, NL Solano, SM Hollingsworth, ZR Menon, AS Frey, AS Spektor, BS Penney, EB Schilling, G Ross, CA Borchelt, DR Tapscott, SJ Young, AB Cha, JHJ Olson, JM
Citation: R. Luthi-carter et al., Decreased expression of striatal signaling genes in a mouse model of Huntington's disease, HUM MOL GEN, 9(9), 2000, pp. 1259-1271
Amyloid precursor proteins inhibit heme oxygenase activity and augment neurotoxicity in Alzheimer's disease
Authors: Takahashi, M Dore, S Ferris, CD Tomita, T Sawa, A Wolosker, H Borchelt, DR Iwatsubo, T Kim, SH Thinakaran, G Sisodia, SS Snyder, SH
Citation: M. Takahashi et al., Amyloid precursor proteins inhibit heme oxygenase activity and augment neurotoxicity in Alzheimer's disease, NEURON, 28(2), 2000, pp. 461-473
SOD1 rescues cerebral endothelial dysfunction in mice overexpressing amyloid precursor protein
Authors: Iadecola, C Zhang, FY Niwa, K Eckman, C Turner, SK Fischer, E Younkin, S Borchelt, DR Hsiao, KK Carlson, GA
Citation: C. Iadecola et al., SOD1 rescues cerebral endothelial dysfunction in mice overexpressing amyloid precursor protein, NAT NEUROSC, 2(2), 1999, pp. 157-161
Synaptic transmission and hippocampal long-term potentiation in transgenicmice expressing FAD-linked presenilin 1
Authors: Parent, A Linden, DJ Sisodia, SS Borchelt, DR
Citation: A. Parent et al., Synaptic transmission and hippocampal long-term potentiation in transgenicmice expressing FAD-linked presenilin 1, NEUROBIOL D, 6(1), 1999, pp. 56-62
Variation in the biochemical/biophysical properties of mutant superoxide dismutase 1 enzymes and the rate of disease progression in familial amyotrophic lateral sclerosis kindreds
Authors: Ratovitski, T Corson, LB Strain, J Wong, P Cleveland, DW Culotta, VC Borchelt, DR
Citation: T. Ratovitski et al., Variation in the biochemical/biophysical properties of mutant superoxide dismutase 1 enzymes and the rate of disease progression in familial amyotrophic lateral sclerosis kindreds, HUM MOL GEN, 8(8), 1999, pp. 1451-1460
Intranuclear inclusions and neuritic aggregates in transgenic mice expressing a mutant N-terminal fragment of huntingtin (vol 8, pg 397, 1999)
Authors: Schilling, G Becher, MW Sharp, AH Jinnah, HA Duan, K Kotzuk, JA Slunt, HH Ratovitski, T Cooper, JK Jenkins, NA Copeland, NG Price, DL Ross, CA Borchelt, DR
Citation: G. Schilling et al., Intranuclear inclusions and neuritic aggregates in transgenic mice expressing a mutant N-terminal fragment of huntingtin (vol 8, pg 397, 1999), HUM MOL GEN, 8(5), 1999, pp. 943-943
Intranuclear inclusions and neuritic aggregates in transgenic mice expressing a mutant N-terminal fragment of huntingtin
Authors: Schilling, G Becher, MW Sharp, AH Jinnah, HA Duan, K Kotzuk, JA Slunt, HH Ratovitski, T Cooper, JK Jenkins, NA Copeland, NG Price, DL Ross, CA Borchelt, DR
Citation: G. Schilling et al., Intranuclear inclusions and neuritic aggregates in transgenic mice expressing a mutant N-terminal fragment of huntingtin, HUM MOL GEN, 8(3), 1999, pp. 397-407
Polyglutamine pathogenesis
Authors: Ross, CA Wood, JD Schilling, G Peters, MF Nucifora, FC Cooper, JK Sharp, AH Margolis, RL Borchelt, DR
Citation: Ca. Ross et al., Polyglutamine pathogenesis, PHI T ROY B, 354(1386), 1999, pp. 1005-1011
Nuclear accumulation of truncated atrophin-1 fragments in a transgenic mouse model of DRPLA
Authors: Schilling, G Wood, JD Kui, DA Slunt, HH Gonzales, V Yamada, M Cooper, JK Margolis, RL Jenkins, NA Copeland, NG Takahashi, H Tsuji, S Price, DL Borchelt, DR Ross, CA
Citation: G. Schilling et al., Nuclear accumulation of truncated atrophin-1 fragments in a transgenic mouse model of DRPLA, NEURON, 24(1), 1999, pp. 275-286
Caspase-1 is activated in neural cells and tissue with amyotrophic lateralsclerosis-associated mutations in copper-zinc superoxide dismutase (vol 95, pg 15763, 1998)
Authors: Pasinelli, P Borchelt, DR Houseweart, MK Cleveland, DW Brown, RH
Citation: P. Pasinelli et al., Caspase-1 is activated in neural cells and tissue with amyotrophic lateralsclerosis-associated mutations in copper-zinc superoxide dismutase (vol 95, pg 15763, 1998), P NAS US, 96(6), 1999, pp. 3330-3330
Function and dysfunction of presenilins in Alzheimer's disease
Authors: Sisodia, SS Thinakaran, G Borchelt, DR Wong, PC Lee, MK Price, DL
Citation: Ss. Sisodia et al., Function and dysfunction of presenilins in Alzheimer's disease, ALZHEIMER'S DISEASE AND RELATED DISORDERS, 1999, pp. 333-346
Effects of PS1 deficiency on membrane protein trafficking in neurons
Authors: Naruse, S Thinakaran, G Luo, JJ Kusiak, JW Tomita, T Iwatsubo, T Qian, XZ Ginty, DD Price, DL Borchelt, DR Wong, PC Sisodia, SS
Citation: S. Naruse et al., Effects of PS1 deficiency on membrane protein trafficking in neurons, NEURON, 21(5), 1998, pp. 1213-1221
Alzheimer's disease: Genetic studies and transgenic models
Authors: Price, DL Tanzi, RE Borchelt, DR Sisodia, SS
Citation: Dl. Price et al., Alzheimer's disease: Genetic studies and transgenic models, ANN R GENET, 32, 1998, pp. 461-493
Caspase-1 is activated in neural cells and tissue with amyotrophic lateralsclerosis-associated mutations in copper-zinc superoxide dismutase
Authors: Pasinelli, P Borchelt, DR Houseweart, MK Cleveland, DW Brown, RH
Citation: P. Pasinelli et al., Caspase-1 is activated in neural cells and tissue with amyotrophic lateralsclerosis-associated mutations in copper-zinc superoxide dismutase, P NAS US, 95(26), 1998, pp. 15763-15768
Inherited neurodegenerative diseases and transgenic models
Authors: Borchelt, DR
Citation: Dr. Borchelt, Inherited neurodegenerative diseases and transgenic models, LAB ANIM SC, 48(6), 1998, pp. 604-610
Risultati: 1-24 |