Authors:
Borthwick, AD
Crame, AJ
Davies, DE
Exall, AM
Jackson, DL
Mason, AM
Pennell, AMK
Weingarten, GG
Citation: Ad. Borthwick et al., Stereoselective synthesis of alpha-methyl and beta-methyl pyrrolidine 5,5-trans-lactam (5-oxo-hexahydro-pyrrolo[3,2-b]pyrrole) and stereoselective alkylation of the strained pyrrolidine 5,5-trans-lactam ring system, SYNLETT, (4), 2000, pp. 504-508
Authors:
Borthwick, AD
Angier, SJ
Crame, AJ
Exall, AM
Haley, TM
Hart, GJ
Mason, AM
Pennell, AMK
Weingarten, GG
Citation: Ad. Borthwick et al., Design and synthesis of pyrrolidine-5,5-trans-lactams (5-oxo-hexahydro-pyrrolo[3,2-b]pyrroles) as novel mechanism-based inhibitors of human cytomegalovirus protease. 1. The alpha-methyl-trans-lactam template, J MED CHEM, 43(23), 2000, pp. 4452-4464
Authors:
Borthwick, AD
Crame, A
Exall, A
Mason, A
Pennell, A
Citation: Ad. Borthwick et al., An improved synthesis of the strained pyrrolidine-5,5-translactam ring system, TETRAHEDR L, 40(15), 1999, pp. 3061-3062
Authors:
Haley, TM
Angier, SJ
Borthwick, AD
Montgomery, DS
Purvis, IJ
Smart, DH
Bessant, C
Van Wely, C
Hart, GJ
Citation: Tm. Haley et al., Investigation of the covalent modification of the catalytic triad of humancytomegalovirus protease by pseudo-reversible beta-lactam inhibitors and apeptide chloromethylketone, J MASS SPEC, 33(12), 1998, pp. 1246-1255