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Results: 1-13 |
Results: 13
Novel (4-piperazin-1-ylquinolin-6-yl) arylsulfonamides with high affinity and selectivity for the 5-HT6 receptor
Authors: Bromidge, SM Griffith, K Heightman, TD Jennings, A King, FD Moss, SF Newman, H Riley, G Routledge, C Serafinowska, HT Thomas, DR
Citation: Sm. Bromidge et al., Novel (4-piperazin-1-ylquinolin-6-yl) arylsulfonamides with high affinity and selectivity for the 5-HT6 receptor, BIOORG MED, 11(21), 2001, pp. 2843-2846
Phenyl benzenesulfonamides are novel and selective 5-HT6 antagonists: Identification of N-(2,5-dibromo-3-fluorophenyl)-4-methoxy-3-piperazin-1-ylbenzenesulfonamide (SB-357134)
Authors: Bromidge, SM Clarke, SE Gager, T Griffith, K Jeffrey, P Jennings, AJ Joiner, GF King, FD Lovell, PJ Moss, SF Newman, H Riley, G Rogers, D Routledge, C Serafinowska, H Smith, DR
Citation: Sm. Bromidge et al., Phenyl benzenesulfonamides are novel and selective 5-HT6 antagonists: Identification of N-(2,5-dibromo-3-fluorophenyl)-4-methoxy-3-piperazin-1-ylbenzenesulfonamide (SB-357134), BIOORG MED, 11(1), 2001, pp. 55-58
SB-243213; a selective 5-HT2C receptor inverse agonist with improved anxiolytic profile: lack of tolerance and withdrawal anxiety
Authors: Wood, MD Reavill, C Trail, B Wilson, A Stean, T Kennett, GA Lightowler, S Blackburn, TP Thomas, D Gager, TL Riley, G Holland, V Bromidge, SM Forbes, IT Middlemiss, DN
Citation: Md. Wood et al., SB-243213; a selective 5-HT2C receptor inverse agonist with improved anxiolytic profile: lack of tolerance and withdrawal anxiety, NEUROPHARM, 41(2), 2001, pp. 186-199
1-[2-[(heteroaryloxy)heteroaryl]carbamoyl]indolines: Novel and selective 5-HT2C receptor inverse agonists with potential as antidepressant/anxiolyticagents
Authors: Bromidge, SM Dabbs, S Davies, S Duckworth, DM Forbes, IT Jones, GE Jones, J King, FD Saunders, DV Blackburn, TP Holland, V Kennett, GA Lightowler, S Middlemiss, DN Riley, GJ Trail, B Wood, MD
Citation: Sm. Bromidge et al., 1-[2-[(heteroaryloxy)heteroaryl]carbamoyl]indolines: Novel and selective 5-HT2C receptor inverse agonists with potential as antidepressant/anxiolyticagents, BIOORG MED, 10(16), 2000, pp. 1863-1866
1-[2-[(heteroarylmethoxy)aryl]carbamoyl]indolines are selective and orallyactive 5-HT2C receptor inverse agonists
Authors: Bromidge, SM Davies, S Duckworth, DM Forbes, IT Jones, GE Jones, J King, FD Blackburn, TP Holland, V Kennett, GA Lightowler, S Middlemiss, DN Riley, GJ Trail, B Wood, MD
Citation: Sm. Bromidge et al., 1-[2-[(heteroarylmethoxy)aryl]carbamoyl]indolines are selective and orallyactive 5-HT2C receptor inverse agonists, BIOORG MED, 10(16), 2000, pp. 1867-1870
Biarylcarbamoylindolines are novel and selective 5-HT2C receptor inverse agonists: Identification of 5-methyl-1-[[2-[(2-methyl-3-pyridyl)oxy]-5-pyridyl]carbamoyl]-6-trifluoromethylindoline (SB-243213) as a potential antidepressant/anxiolytic agent
Authors: Bromidge, SM Dabbs, S Davies, DT Davies, S Duckworth, DM Forbes, IT Gaster, LM Ham, P Jones, GE King, FD Mulholland, KR Saunders, DV Wyman, PA Blaney, FE Clarke, SE Blackburn, TP Holland, V Kennett, GA Lightowler, S Middlemiss, DN Trail, B Riley, GJ Wood, MD
Citation: Sm. Bromidge et al., Biarylcarbamoylindolines are novel and selective 5-HT2C receptor inverse agonists: Identification of 5-methyl-1-[[2-[(2-methyl-3-pyridyl)oxy]-5-pyridyl]carbamoyl]-6-trifluoromethylindoline (SB-243213) as a potential antidepressant/anxiolytic agent, J MED CHEM, 43(6), 2000, pp. 1123-1134
A novel, potent, and selective 5-HT7 antagonist: (R)-3-(2-(2-(4-methylpiperidin-1-yl)-ethyl)pyrrolidine-1-sulfonyl)phenol (SB-269970)
Authors: Lovell, PJ Bromidge, SM Dabbs, S Duckworth, DM Forbes, IT Jennings, AJ King, FD Middlemiss, DN Rahman, SK Saunders, DV Collin, LL Hagan, JJ Riley, GJ Thomas, DR
Citation: Pj. Lovell et al., A novel, potent, and selective 5-HT7 antagonist: (R)-3-(2-(2-(4-methylpiperidin-1-yl)-ethyl)pyrrolidine-1-sulfonyl)phenol (SB-269970), J MED CHEM, 43(3), 2000, pp. 342-345
Characterization of [I-125]-SB-258585 binding to human recombinant and native 5-HT6 receptors in rat, pig and human brain tissue
Authors: Hirst, WD Minton, JAL Bromidge, SM Moss, SF Latter, AJ Riley, G Routledge, C Middlemiss, DN Price, GW
Citation: Wd. Hirst et al., Characterization of [I-125]-SB-258585 binding to human recombinant and native 5-HT6 receptors in rat, pig and human brain tissue, BR J PHARM, 130(7), 2000, pp. 1597-1605
Characterization of SB-271046: A potent, selective and orally active 5-HT6receptor antagonist
Authors: Routledge, C Bromidge, SM Moss, SF Price, GW Hirst, W Newman, H Riley, G Gager, T Stean, T Upton, N Clarke, SE Brown, AM Middlemiss, DN
Citation: C. Routledge et al., Characterization of SB-271046: A potent, selective and orally active 5-HT6receptor antagonist, BR J PHARM, 130(7), 2000, pp. 1606-1612
Characterization of SB-269970-A, a selective 5-HT7 receptor antagonist
Authors: Hagan, JJ Price, GW Jeffrey, P Deeks, NJ Stean, T Piper, D Smith, MI Upton, N Medhurst, AD Middlemiss, DN Riley, GJ Lovell, PJ Bromidge, SM Thomas, DR
Citation: Jj. Hagan et al., Characterization of SB-269970-A, a selective 5-HT7 receptor antagonist, BR J PHARM, 130(3), 2000, pp. 539-548
[H-3]-SB-269970 - A selective antagonist radioligand for 5-HT7 receptors
Authors: Thomas, DR Atkinson, PJ Ho, M Bromidge, SM Lovell, PJ Villani, AJ Hagan, JJ Middlemiss, DN Price, GW
Citation: Dr. Thomas et al., [H-3]-SB-269970 - A selective antagonist radioligand for 5-HT7 receptors, BR J PHARM, 130(2), 2000, pp. 409-417
Model studies on a synthetically facile series of N-substituted phenyl-N '-pyridin-3-yl ureas leading to 1-(3-pyridylcarbamoyl) indolines that are potent and selective 5-HT2C/2B receptor antagonists
Authors: Bromidge, SM Dabbs, S Davies, DT Davies, S Duckworth, DM Forbes, IT Gadre, A Ham, P Jones, GE King, FD Saunders, DV Thewlis, KM Vyas, D Blackburn, TP Holland, V Kennett, GA Riley, GJ Wood, MD
Citation: Sm. Bromidge et al., Model studies on a synthetically facile series of N-substituted phenyl-N '-pyridin-3-yl ureas leading to 1-(3-pyridylcarbamoyl) indolines that are potent and selective 5-HT2C/2B receptor antagonists, BIO MED CH, 7(12), 1999, pp. 2767-2773
5-chloro-N-(4-methoxy-3-piperazin-1-yl-phenyl)-3-methyl-2-benzothiophenesulfonamide (SB-271046): A potent, selective, and orally bioavailable 5-HT6 receptor antagonist
Authors: Bromidge, SM Brown, AM Clarke, SE Dodgson, K Gager, T Grassam, HL Jeffrey, PM Joiner, GF King, FD Middlemiss, DN Moss, SF Newman, H Riley, G Routledge, C Wyman, P
Citation: Sm. Bromidge et al., 5-chloro-N-(4-methoxy-3-piperazin-1-yl-phenyl)-3-methyl-2-benzothiophenesulfonamide (SB-271046): A potent, selective, and orally bioavailable 5-HT6 receptor antagonist, J MED CHEM, 42(2), 1999, pp. 202-205
Risultati: 1-13 |