AAAAAA

   
Results: 1-17 |
Results: 17
Inhibition of substrate synthesis as a strategy for glycolipid lysosomal storage disease therapy
Authors: Platt, FM Jeyakumar, M Andersson, U Priestman, DA Dwek, RA Butters, TD Cox, TM Lachmann, RH Hollak, C Aerts, JMFG Van Weely, S Hrebicek, M Moyses, C Gow, I Elstein, D Zimran, A
Citation: Fm. Platt et al., Inhibition of substrate synthesis as a strategy for glycolipid lysosomal storage disease therapy, J INH MET D, 24(2), 2001, pp. 275-290
Study of the mechanism of antiviral action of iminosugar derivatives against bovine viral diarrhea virus
Authors: Durantel, D Branza-Nichita, N Carrouee-Durantel, S Butters, TD Dwek, RA Zitzmann, N
Citation: D. Durantel et al., Study of the mechanism of antiviral action of iminosugar derivatives against bovine viral diarrhea virus, J VIROLOGY, 75(19), 2001, pp. 8987-8998
Enhanced survival in Sandhoff disease mice receiving a combination of substrate deprivation therapy and bone marrow transplantation
Authors: Jeyakumar, M Norflus, F Tifft, CJ Cortina-Borja, M Butters, TD Proia, RL Perry, VH Dwek, RA Platt, FM
Citation: M. Jeyakumar et al., Enhanced survival in Sandhoff disease mice receiving a combination of substrate deprivation therapy and bone marrow transplantation, BLOOD, 97(1), 2001, pp. 327-329
High-performance liquid chromatography analysis of ganglioside carbohydrates at the picomole level after ceramide glycanase digestion and fluorescentlabeling with 2-aminobenzamide
Authors: Wing, DR Garner, B Hunnam, V Reinkensmeier, G Andersson, U Harvey, DJ Dwek, RA Platt, FM Butters, TD
Citation: Dr. Wing et al., High-performance liquid chromatography analysis of ganglioside carbohydrates at the picomole level after ceramide glycanase digestion and fluorescentlabeling with 2-aminobenzamide, ANALYT BIOC, 298(2), 2001, pp. 207-217
Imino sugar therapy for type 1 Gaucher disease
Authors: Priestman, DA Platt, FM Dwek, RA Butters, TD
Citation: Da. Priestman et al., Imino sugar therapy for type 1 Gaucher disease, GLYCOBIOLOG, 10(11), 2000, pp. IV-VI
Fluorescence labelling of carbohydrates with 2-aminobenzamide (2AB)
Authors: France, RR Cumpstey, I Butters, TD Fairbanks, AJ Wormald, MR
Citation: Rr. France et al., Fluorescence labelling of carbohydrates with 2-aminobenzamide (2AB), TETRAHEDR-A, 11(24), 2000, pp. 4985-4994
Molecular requirements of imino sugars for the selective control of N-linked glycosylation and glycosphingolipid biosynthesis
Authors: Butters, TD van den Broek, LAGM Fleet, GWJ Krulle, TM Wormald, MR Dwek, RA Platt, FM
Citation: Td. Butters et al., Molecular requirements of imino sugars for the selective control of N-linked glycosylation and glycosphingolipid biosynthesis, TETRAHEDR-A, 11(1), 2000, pp. 113-124
Inhibition of glycosphingolipid biosynthesis: Application to lysosomal storage disorders
Authors: Butters, TD Dwek, RA Platt, FM
Citation: Td. Butters et al., Inhibition of glycosphingolipid biosynthesis: Application to lysosomal storage disorders, CHEM REV, 100(12), 2000, pp. 4683
N-butyldeoxygalactonojirimycin: A more selective inhibitor of glycosphingolipid biosynthesis than N-butyldeoxynojirimycin, in vitro and in vivo
Authors: Andersson, U Butters, TD Dwek, RA Platt, FM
Citation: U. Andersson et al., N-butyldeoxygalactonojirimycin: A more selective inhibitor of glycosphingolipid biosynthesis than N-butyldeoxynojirimycin, in vitro and in vivo, BIOCH PHARM, 59(7), 2000, pp. 821-829
High-performance cation-exchange chromatography and pulsed amperometric detection for the separation, detection, and quantitation of N-alkylated imino sugars in biological samples
Authors: Mellor, HR Adam, A Platt, FM Dwek, RA Butters, TD
Citation: Hr. Mellor et al., High-performance cation-exchange chromatography and pulsed amperometric detection for the separation, detection, and quantitation of N-alkylated imino sugars in biological samples, ANALYT BIOC, 284(1), 2000, pp. 136-142
Effects of N-butyldeoxynojirimycin and the Lec3.2.8.1 mutant phenotype on N-glycan processing in Chinese hamster ovary cells: Application to glycoprotein crystallization
Authors: Butters, TD Sparks, LM Harlos, K Ikemizu, S Stuart, DI Jones, EY Davis, SJ
Citation: Td. Butters et al., Effects of N-butyldeoxynojirimycin and the Lec3.2.8.1 mutant phenotype on N-glycan processing in Chinese hamster ovary cells: Application to glycoprotein crystallization, PROTEIN SCI, 8(8), 1999, pp. 1696-1701
Synthesis and biological evaluation of enantiomeric rhamnose analogues of the antitumour agent spicamycin - is the mode of action by modification of N-linked glycoproteins?
Authors: Martin, A Butters, TD Fleet, GWJ
Citation: A. Martin et al., Synthesis and biological evaluation of enantiomeric rhamnose analogues of the antitumour agent spicamycin - is the mode of action by modification of N-linked glycoproteins?, TETRAHEDR-A, 10(12), 1999, pp. 2343-2360
Synthesis of homorhamnojirimycins and related trihydroxypipecolic acid derivatives via divergent bicyclic amino lactone intermediates: Inhibition of naringinase (L-rhamnosidase) and dTDP-rhamnose biosynthesis
Authors: Shilvock, JP Wheatley, JR Nash, RJ Watson, AA Griffiths, RC Butters, TD Muller, M Watkin, DJ Winkler, DA Fleet, GWJ
Citation: Jp. Shilvock et al., Synthesis of homorhamnojirimycins and related trihydroxypipecolic acid derivatives via divergent bicyclic amino lactone intermediates: Inhibition of naringinase (L-rhamnosidase) and dTDP-rhamnose biosynthesis, J CHEM S P1, (19), 1999, pp. 2735-2745
Piperidine analogues of D-galactose as potent inhibitors of alpha-galactosidase: Synthesis by stannane-mediated hydroxymethylation of 5-azido-1,4-lactones. Structural relationships between D-galactosidase and L-rhamnosidase inhibitors
Authors: Shilvock, JP Nash, RJ Watson, AA Winters, AL Butters, TD Dwek, RA Winkler, DA Fleet, GWJ
Citation: Jp. Shilvock et al., Piperidine analogues of D-galactose as potent inhibitors of alpha-galactosidase: Synthesis by stannane-mediated hydroxymethylation of 5-azido-1,4-lactones. Structural relationships between D-galactosidase and L-rhamnosidase inhibitors, J CHEM S P1, (19), 1999, pp. 2747-2754
Synthesis of bis(1,3-dihydroxy-isopropyl)amine by reductive amination of dihydroxyacetone: Open chain equivalent of DMDP and a potential AB(4) dendritic monomer
Authors: Scott, DA Krulle, TM Finn, M Nash, RJ Winters, AL Asano, N Butters, TD Fleet, GWJ
Citation: Da. Scott et al., Synthesis of bis(1,3-dihydroxy-isopropyl)amine by reductive amination of dihydroxyacetone: Open chain equivalent of DMDP and a potential AB(4) dendritic monomer, TETRAHEDR L, 40(42), 1999, pp. 7581-7584
Imino sugars inhibit the formation and secretion of bovine viral diarrhea virus, a pestivirus model of hepatitis C virus: Implications for the development of broad spectrum anti-hepatitis virus agents
Authors: Zitzmann, N Mehta, AS Carrouee, S Butters, TD Platt, FM McCauley, J Blumberg, BS Dwek, RA Block, TM
Citation: N. Zitzmann et al., Imino sugars inhibit the formation and secretion of bovine viral diarrhea virus, a pestivirus model of hepatitis C virus: Implications for the development of broad spectrum anti-hepatitis virus agents, P NAS US, 96(21), 1999, pp. 11878-11882
Delayed symptom onset and increased life expectancy in Sandhoff disease mice treated with N-butyldeoxynojirimycin
Authors: Jeyakumar, M Butters, TD Cortina-Borja, M Hunnam, V Proia, RL Perry, VH Dwek, RA Platt, FM
Citation: M. Jeyakumar et al., Delayed symptom onset and increased life expectancy in Sandhoff disease mice treated with N-butyldeoxynojirimycin, P NAS US, 96(11), 1999, pp. 6388-6393
Risultati: 1-17 |