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Results: 1-25 | 26-43
Results: 1-25/43
IDENTIFICATION OF SIDE-CHAINS ON 1,2,5-THIADIAZOLE-AZACYCLES OPTIMAL FOR MUSCARINIC M1 RECEPTOR ACTIVATION
Authors: SAUERBERG P JEPPESEN L OLESEN PH SHEARDOWN MJ FINKJENSEN A RASMUSSEN T RIMVALL K SHANNON HE BYMASTER FP DELAPP NW CALLIGARO DO WARD JS WHITESITT CA THOMSEN C
Citation: P. Sauerberg et al., IDENTIFICATION OF SIDE-CHAINS ON 1,2,5-THIADIAZOLE-AZACYCLES OPTIMAL FOR MUSCARINIC M1 RECEPTOR ACTIVATION, Bioorganic & medicinal chemistry letters, 8(20), 1998, pp. 2897-2902
1,2,5-THIADIAZOLE ANALOGS OF ACECLIDINE AS POTENT M(1) MUSCARINIC AGONISTS
Authors: WARD JS MERRITT L CALLIGARO DO BYMASTER FP SHANNON HE MITCH CH WHITESITT C BRUNSTING D SHEARDOWN MJ OLESEN PH SWEDBERG MDB JEPPESEN L SAUERBERG P
Citation: Js. Ward et al., 1,2,5-THIADIAZOLE ANALOGS OF ACECLIDINE AS POTENT M(1) MUSCARINIC AGONISTS, Journal of medicinal chemistry, 41(3), 1998, pp. 379-392
MUSCARINIC AGONISTS WITH ANTIPSYCHOTIC-LIKE ACTIVITY - STRUCTURE-ACTIVITY-RELATIONSHIPS OF 1,2,5-THIADIAZOLE ANALOGS WITH FUNCTIONAL DOPAMINE ANTAGONIST ACTIVITY
Authors: SAUERBERG P JEPPESEN L OLESEN PH RASMUSSEN T SWEDBERG MDB SHEARDOWN MJ FINKJENSEN A THOMSEN C THOGERSEN H RIMVALL K WARD JS CALLIGARO DO DELAPP NW BYMASTER FP SHANNON HE
Citation: P. Sauerberg et al., MUSCARINIC AGONISTS WITH ANTIPSYCHOTIC-LIKE ACTIVITY - STRUCTURE-ACTIVITY-RELATIONSHIPS OF 1,2,5-THIADIAZOLE ANALOGS WITH FUNCTIONAL DOPAMINE ANTAGONIST ACTIVITY, Journal of medicinal chemistry, 41(22), 1998, pp. 4378-4384
SYNTHESIS AND STRUCTURE-ACTIVITY-RELATIONSHIPS OF POTENT AND ORALLY-ACTIVE 5-HT4 RECEPTOR ANTAGONISTS - INDAZOLE AND BENZIMIDAZOLONE DERIVATIVES
Authors: SCHAUS JM THOMPSON DC BLOOMQUIST WE SUSEMICHEL AD CALLIGARO DO COHEN ML
Citation: Jm. Schaus et al., SYNTHESIS AND STRUCTURE-ACTIVITY-RELATIONSHIPS OF POTENT AND ORALLY-ACTIVE 5-HT4 RECEPTOR ANTAGONISTS - INDAZOLE AND BENZIMIDAZOLONE DERIVATIVES, Journal of medicinal chemistry, 41(11), 1998, pp. 1943-1955
CONFORMATIONALLY CONSTRAINED ANALOGS OF THE MUSCARINIC AGONIST IADIAZOL-3-YL)-1,2,5,6-TETRAHYDRO-1-METHYLPYRIDINE - SYNTHESIS, RECEPTOR AFFINITY, AND ANTINOCICEPTIVE ACTIVITY
Authors: SAUERBERG P OLESEN PH SHEARDOWN MJ RIMVALL K THOGERSEN H SHANNON HE SAWYER BD WARD JS BYMASTER FP DELAPP NW CALLIGARO DO SWEDBERG MDB
Citation: P. Sauerberg et al., CONFORMATIONALLY CONSTRAINED ANALOGS OF THE MUSCARINIC AGONIST IADIAZOL-3-YL)-1,2,5,6-TETRAHYDRO-1-METHYLPYRIDINE - SYNTHESIS, RECEPTOR AFFINITY, AND ANTINOCICEPTIVE ACTIVITY, Journal of medicinal chemistry, 41(1), 1998, pp. 109-116
UNEXPECTED ANTIPSYCHOTIC-LIKE ACTIVITY WITH THE MUSCARINIC RECEPTOR-LIGAND O-1,2,5-THIADIAZOL-4-YL)-1-AZABICYCLO[3.2.1]OCTANE
Authors: BYMASTER FP SHANNON HE RASMUSSEN K DELAPP NW MITCH CH WARD JS CALLIGARO DO LUDVIGSEN TS SHEARDOWN MJ OLESEN PH SWEDBERG MDB SAUERBERG P FINKJENSEN A
Citation: Fp. Bymaster et al., UNEXPECTED ANTIPSYCHOTIC-LIKE ACTIVITY WITH THE MUSCARINIC RECEPTOR-LIGAND O-1,2,5-THIADIAZOL-4-YL)-1-AZABICYCLO[3.2.1]OCTANE, European journal of pharmacology, 356(2-3), 1998, pp. 109-119
XANOMELINE COMPARED TO OTHER MUSCARINIC AGENTS ON STIMULATION OF PHOSPHOINOSITIDE HYDROLYSIS IN-VIVO AND OTHER CHOLINOMIMETIC EFFECTS
Authors: BYMASTER FP CARTER PA PETERS SC ZHANG W WARD JS MITCH CH CALLIGARO DO WHITESITT CA DELAPP N SHANNON HE RIMVALL K JEPPESEN L SHEARDOWN MJ FINKJENSEN A SAUERBERG P
Citation: Fp. Bymaster et al., XANOMELINE COMPARED TO OTHER MUSCARINIC AGENTS ON STIMULATION OF PHOSPHOINOSITIDE HYDROLYSIS IN-VIVO AND OTHER CHOLINOMIMETIC EFFECTS, Brain research, 795(1-2), 1998, pp. 179-190
THE SYNTHESIS AND BIOLOGICAL-ACTIVITY OF SOME KNOWN AND PUTATIVE METABOLITES OF THE ATYPICAL ANTIPSYCHOTIC AGENT OLANZAPINE (LY170053)
Authors: CALLIGARO DO FAIRHURST J HOTTEN TM MOORE NA TUPPER DE
Citation: Do. Calligaro et al., THE SYNTHESIS AND BIOLOGICAL-ACTIVITY OF SOME KNOWN AND PUTATIVE METABOLITES OF THE ATYPICAL ANTIPSYCHOTIC AGENT OLANZAPINE (LY170053), Bioorganic & medicinal chemistry letters, 7(1), 1997, pp. 25-30
XANOMELINE - A SELECTIVE MUSCARINIC AGONIST FOR THE TREATMENT OF ALZHEIMERS-DISEASE
Authors: BYMASTER FP WHITESITT CA SHANNON HE DELAPP N WARD JS CALLIGARO DO SHIPLEY LA BUELKESAM JL BODICK NC FARDE L SHEARDOWN MJ OLESEN PH HANSEN KT SUZDAK PD SWEDBERG MDB SAUERBERG P MITCH CH
Citation: Fp. Bymaster et al., XANOMELINE - A SELECTIVE MUSCARINIC AGONIST FOR THE TREATMENT OF ALZHEIMERS-DISEASE, Drug development research, 40(2), 1997, pp. 158-170
PHARMACOLOGICAL PROFILE OF LY301317, A POTENT AND SELECTIVE 5-HT1A AGONIST
Authors: WOLFF MC BENVENGA MJ CALLIGARO DO FULLER RW GIDDA JS HEMRICKLUECKE S LUCOT JB NELSON DL OVERSHINER CD LEANDER JD
Citation: Mc. Wolff et al., PHARMACOLOGICAL PROFILE OF LY301317, A POTENT AND SELECTIVE 5-HT1A AGONIST, Drug development research, 40(1), 1997, pp. 17-34
IN-VITRO AND IN-VIVO BIOCHEMISTRY OF OLANZAPINE - A NOVEL, ATYPICAL ANTIPSYCHOTIC DRUG
Authors: BYMASTER FP RASMUSSEN K CALLIGARO DO NELSON DL DELAPP NW WONG DT MOORE NA
Citation: Fp. Bymaster et al., IN-VITRO AND IN-VIVO BIOCHEMISTRY OF OLANZAPINE - A NOVEL, ATYPICAL ANTIPSYCHOTIC DRUG, The Journal of clinical psychiatry, 58, 1997, pp. 28-36
CHARACTERIZATION OF LY344864 AS A PHARMACOLOGICAL TOOL TO STUDY 5-HT1F RECEPTORS - BINDING AFFINITIES, BRAIN PENETRATION AND ACTIVITY IN THE NEUROGENIC DURAL INFLAMMATION MODEL OF MIGRAINE
Authors: PHEBUS LA JOHNSON KW ZGOMBICK JM GILBERT PJ VANBELLE K MANCUSO V NELSON DLG CALLIGARO DO KIEFER AD BRANCHEK TA FLAUGH ME
Citation: La. Phebus et al., CHARACTERIZATION OF LY344864 AS A PHARMACOLOGICAL TOOL TO STUDY 5-HT1F RECEPTORS - BINDING AFFINITIES, BRAIN PENETRATION AND ACTIVITY IN THE NEUROGENIC DURAL INFLAMMATION MODEL OF MIGRAINE, Life sciences, 61(21), 1997, pp. 2117-2126
THE TETRAHYDROPYRIDINE RING CONFERS OPTIMAL M(1) SELECTIVITY AND BLOOD-BRAIN-BARRIER PENETRATION AMONG HEXYLOXY-1,2,5-THIADIAZOLE AZACYCLES
Authors: WARD JS MERRITT L STRATFORD R BROWN TJ WIJAYARATNE R SZEWCZYK SP CALLIGARO DO BYMASTER FP SHANNON HE MITCH CH JOHNSON DW WIKEL JH OLESEN MJ SHEARDOWN MJ SWEDBERG MDB SAUERBERG P
Citation: Js. Ward et al., THE TETRAHYDROPYRIDINE RING CONFERS OPTIMAL M(1) SELECTIVITY AND BLOOD-BRAIN-BARRIER PENETRATION AMONG HEXYLOXY-1,2,5-THIADIAZOLE AZACYCLES, Life sciences, 60(13-14), 1997, pp. 6-6
ANTICONVULSANT EFFECTS OF MUSCARINICS
Authors: SWEDBERG MDB SHANNON HE SHEARDOWN MJ KLITGAARD H BYMASTER FP WARD JS MITCH CH OLESEN PH ESKESEN K SUZDAK PD CALLIGARO DO SAUERBERG P
Citation: Mdb. Swedberg et al., ANTICONVULSANT EFFECTS OF MUSCARINICS, Life sciences, 60(13-14), 1997, pp. 80-80
IN-VIVO PHARMACOLOGY OF BUTYLTHIO[2.2.2] (LY297802 NNC11-1053), AN ORALLY ACTING ANTINOCICEPTIVE MUSCARINIC AGONIST/
Authors: SHANNON HE WOMER DE BYMASTER FP CALLIGARO DO DELAPP NC MITCH CH WARD JS WHITESITT CA SWEDBERG MDB SHEARDOWN MJ FINKJENSEN A OLESEN PH RIMVALL K SAUERBERG P
Citation: He. Shannon et al., IN-VIVO PHARMACOLOGY OF BUTYLTHIO[2.2.2] (LY297802 NNC11-1053), AN ORALLY ACTING ANTINOCICEPTIVE MUSCARINIC AGONIST/, Life sciences, 60(13-14), 1997, pp. 969-976
BUTYLTHIO[2.2.2] (NNC 11-1053 LY297802) - AN ORALLY-ACTIVE MUSCARINICAGONIST ANALGESIC/
Authors: SWEDBERG MDB SHEARDOWN MJ SAUERBERG P OLESEN PH SUZDAK PD HANSEN KT BYMASTER FP WARD JS MITCH CH CALLIGARO DO DELAPP NW SHANNON HE
Citation: Mdb. Swedberg et al., BUTYLTHIO[2.2.2] (NNC 11-1053 LY297802) - AN ORALLY-ACTIVE MUSCARINICAGONIST ANALGESIC/, The Journal of pharmacology and experimental therapeutics, 281(2), 1997, pp. 876-883
PHARMACOLOGY OF BUTYLTHIO[2.2.2] (LY297802 NNC11-1053) - A NOVEL ANALGESIC WITH MIXED MUSCARINIC RECEPTOR AGONIST AND ANTAGONIST ACTIVITY/
Authors: SHANNON HE SHEARDOWN MJ BYMASTER FP CALLIGARO DO DELAPP NW GIDDA J MITCH CH SAWYER BD STENGEL PW WARD JS WONG DT OLESEN PH SUZDAK PD SAUERBERG P SWEDBERG MDB
Citation: He. Shannon et al., PHARMACOLOGY OF BUTYLTHIO[2.2.2] (LY297802 NNC11-1053) - A NOVEL ANALGESIC WITH MIXED MUSCARINIC RECEPTOR AGONIST AND ANTAGONIST ACTIVITY/, The Journal of pharmacology and experimental therapeutics, 281(2), 1997, pp. 884-894
MUSCARINIC ANALGESICS WITH POTENT AND SELECTIVE EFFECTS ON THE GASTROINTESTINAL-TRACT - POTENTIAL APPLICATION FOR THE TREATMENT OF IRRITABLE-BOWEL-SYNDROME
Authors: MITCH CH BROWN TJ BYMASTER FP CALLIGARO DO DIECKMAN D MERRIT L PETERS SC QUIMBY SJ SHANNON HE SHIPLEY LA WARD JS HANSEN K OLESEN PH SAUERBERG P SHEARDOWN MJ SWEDBERG MDB SUZDAK P GREENWOOD B
Citation: Ch. Mitch et al., MUSCARINIC ANALGESICS WITH POTENT AND SELECTIVE EFFECTS ON THE GASTROINTESTINAL-TRACT - POTENTIAL APPLICATION FOR THE TREATMENT OF IRRITABLE-BOWEL-SYNDROME, Journal of medicinal chemistry, 40(4), 1997, pp. 538-546
THE ATYPICAL ANTIPSYCHOTIC OLANZAPINE IS AN ANTAGONIST AT DOPAMINE, SEROTONIN AND MUSCARINIC RECEPTOR SUBTYPES
Authors: BYMASTER FP NELSON DL DELAPP NW LUCAITES VL WAINSCOTT DB FALCONE JF ECKOLS K FOREMAN MM CALLIGARO DO
Citation: Fp. Bymaster et al., THE ATYPICAL ANTIPSYCHOTIC OLANZAPINE IS AN ANTAGONIST AT DOPAMINE, SEROTONIN AND MUSCARINIC RECEPTOR SUBTYPES, Schizophrenia research, 18(2-3), 1996, pp. 2-2
RADIORECEPTOR BINDING PROFILE OF THE ATYPICAL ANTIPSYCHOTIC OLANZAPINE
Authors: BYMASTER FP CALLIGARO DO FALCONE JF MARSH RD MOORE NA TYE NC SEEMAN P WONG DT
Citation: Fp. Bymaster et al., RADIORECEPTOR BINDING PROFILE OF THE ATYPICAL ANTIPSYCHOTIC OLANZAPINE, Neuropsychopharmacology, 14(2), 1996, pp. 87-96
LY353433, A POTENT, ORALLY EFFECTIVE, LONG-ACTING 5-HT4 RECEPTOR ANTAGONIST - COMPARISON TO CISAPRIDE AND RS23597-190
Authors: COHEN ML BLOOMQUIST W SCHAUS JM THOMPSON DC SUSEMICHEL AD CALLIGARO DO COHEN I
Citation: Ml. Cohen et al., LY353433, A POTENT, ORALLY EFFECTIVE, LONG-ACTING 5-HT4 RECEPTOR ANTAGONIST - COMPARISON TO CISAPRIDE AND RS23597-190, The Journal of pharmacology and experimental therapeutics, 277(1), 1996, pp. 97-104
DETECTION OF MUSCARINIC ACETYLCHOLINE-RECEPTORS IN THE RAT-KIDNEY USING NESTED PCR
Authors: MEYER JA LASKA DA CALLIGARO DO
Citation: Ja. Meyer et al., DETECTION OF MUSCARINIC ACETYLCHOLINE-RECEPTORS IN THE RAT-KIDNEY USING NESTED PCR, Molecular biology of the cell, 6, 1995, pp. 1232-1232
PHARMACOLOGICAL CHARACTERIZATION OF ENANTIOMERS OF 8-THIOMETHYL-2-(DI-N-PROPYLAMINO)TETRALIN, POTENT AND SELECTIVE 5-HT1A RECEPTOR AGONISTS
Authors: FOREMAN MM FULLER RW LEANDER JD NELSON DL CALLIGARO DO LUCAITES VL WONG DT ZHANG L BARRETT JE SCHAUS JM
Citation: Mm. Foreman et al., PHARMACOLOGICAL CHARACTERIZATION OF ENANTIOMERS OF 8-THIOMETHYL-2-(DI-N-PROPYLAMINO)TETRALIN, POTENT AND SELECTIVE 5-HT1A RECEPTOR AGONISTS, Drug development research, 34(1), 1995, pp. 66-85
MUSCARINIC AGONISTS AS ANALGESICS - ANTINOCICEPTIVE ACTIVITY VERSUS M(1) ACTIVITY - SAR OF ALKYLTHIO-TZTPS AND RELATED 1,2,5-THIADIAZOLE ANALOGS
Authors: SAUERBERG P OLESEN PH SHEARDOWN MJ SUZDAK PD SHANNON HE BYMASTER FP CALLIGARO DO MITCH CH WARD JS SWEDBERG MDB
Citation: P. Sauerberg et al., MUSCARINIC AGONISTS AS ANALGESICS - ANTINOCICEPTIVE ACTIVITY VERSUS M(1) ACTIVITY - SAR OF ALKYLTHIO-TZTPS AND RELATED 1,2,5-THIADIAZOLE ANALOGS, Life sciences, 56(11-12), 1995, pp. 807-814
3-(3-HEXYLOXYPYRAZINYL) QUINUCLIDINE AS A FUNCTIONALLY SELECTIVE M(1)AGONIST
Authors: WARD JS MERRITT L CALLIGARO DO BYMASTER FP SHANNON HE SAWYER BD MITCH CH SHEARDOWN MJ OLESEN PH SUZDAK PD SWEDBERG MDB
Citation: Js. Ward et al., 3-(3-HEXYLOXYPYRAZINYL) QUINUCLIDINE AS A FUNCTIONALLY SELECTIVE M(1)AGONIST, Life sciences, 56(11-12), 1995, pp. 1003-1003
Risultati: 1-25 | 26-43