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Results: 1-25 | 26-38
Results: 1-25/38
CHEMICAL-MODEL STUDIES ON THE MONOAMINE OXIDASE-B CATALYZED OXIDATIONOF 4-SUBSTITUTED 1-CYCLOPROPYL-1,2,3,6-TETRAHYDROPYRIDINES
Authors: FRANOT C MABIC S CASTAGNOLI N
Citation: C. Franot et al., CHEMICAL-MODEL STUDIES ON THE MONOAMINE OXIDASE-B CATALYZED OXIDATIONOF 4-SUBSTITUTED 1-CYCLOPROPYL-1,2,3,6-TETRAHYDROPYRIDINES, Bioorganic & medicinal chemistry, 6(3), 1998, pp. 283-291
1-METHYL-3-PYRROLINES AND 2-METHYLISOINDOLINES - NEW CLASSES OF CYCLIC TERTIARY AMINE MONOAMINE-OXIDASE-B SUBSTRATES
Authors: WANG YX MABIC S CASTAGNOLI N
Citation: Yx. Wang et al., 1-METHYL-3-PYRROLINES AND 2-METHYLISOINDOLINES - NEW CLASSES OF CYCLIC TERTIARY AMINE MONOAMINE-OXIDASE-B SUBSTRATES, Bioorganic & medicinal chemistry, 6(2), 1998, pp. 143-149
ELECTRON IONIZATION-INDUCED LOSS OF A METHYL RADICAL FROM CLOPROPYL-4-SUBSTITUTED-1,2,3,6-TETRAHYDROPYRIDINE DERIVATIVES
Authors: MABIC S NIMKAR SK HARRIS DN HARICH K CASTAGNOLI N
Citation: S. Mabic et al., ELECTRON IONIZATION-INDUCED LOSS OF A METHYL RADICAL FROM CLOPROPYL-4-SUBSTITUTED-1,2,3,6-TETRAHYDROPYRIDINE DERIVATIVES, Journal of the American Society for Mass Spectrometry, 8(7), 1997, pp. 724-726
CHEMICAL-MODEL STUDIES ON THE MONOAMINE OXIDASE-B CATALYZED OXIDATIONOF 4-SUBSTITUTED 1-METHYL-1,2,3,6-TETRAHYDROPYRIDINES
Authors: FRANOT C MABIC S CASTAGNOLI N
Citation: C. Franot et al., CHEMICAL-MODEL STUDIES ON THE MONOAMINE OXIDASE-B CATALYZED OXIDATIONOF 4-SUBSTITUTED 1-METHYL-1,2,3,6-TETRAHYDROPYRIDINES, Bioorganic & medicinal chemistry, 5(8), 1997, pp. 1519-1529
POTENTIAL LATENT NITROGEN-MUSTARD DERIVATIVES DESIGNED TO TARGET MONOAMINE-OXIDASE RICH CELLS
Authors: WANG YX CASTAGNOLI N
Citation: Yx. Wang et N. Castagnoli, POTENTIAL LATENT NITROGEN-MUSTARD DERIVATIVES DESIGNED TO TARGET MONOAMINE-OXIDASE RICH CELLS, Bioorganic & medicinal chemistry, 5(7), 1997, pp. 1321-1325
POTENTIAL METABOLIC BIOACTIVATION PATHWAYS INVOLVING CYCLIC TERTIARY-AMINES AND AZAARENES
Authors: CASTAGNOLI N RIMOLDI JM BLOOMQUIST J CASTAGNOLI KP
Citation: N. Castagnoli et al., POTENTIAL METABOLIC BIOACTIVATION PATHWAYS INVOLVING CYCLIC TERTIARY-AMINES AND AZAARENES, Chemical research in toxicology, 10(9), 1997, pp. 924-940
THE NEURONAL NITRIC-OXIDE SYNTHASE INHIBITOR 7-NITROINDAZOLE ALSO INHIBITS THE MONOAMINE OXIDASE-B-CATALYZED OXIDATION OF 1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE
Authors: CASTAGNOLI K PALMER S ANDERSON A BUETERS T CASTAGNOLI N
Citation: K. Castagnoli et al., THE NEURONAL NITRIC-OXIDE SYNTHASE INHIBITOR 7-NITROINDAZOLE ALSO INHIBITS THE MONOAMINE OXIDASE-B-CATALYZED OXIDATION OF 1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE, Chemical research in toxicology, 10(4), 1997, pp. 364-368
REGIOSELECTIVE DEUTERIUM LABELING OF 1,4-DISUBSTITUTED-1,2,3,6-TETRAHYDROPYRIDINES
Authors: MABIC S RIMOLDI JM CASTAGNOLI N
Citation: S. Mabic et al., REGIOSELECTIVE DEUTERIUM LABELING OF 1,4-DISUBSTITUTED-1,2,3,6-TETRAHYDROPYRIDINES, Journal of labelled compounds & radiopharmaceuticals, 39(5), 1997, pp. 409-423
CONFORMATIONAL DISTRIBUTION OF THE POTENTIALLY NEUROTOXIC METABOLITE OF HALOPERIDOL, HPP-SPECTROSCOPY, X-RAY CRYSTALLOGRAPHY AND MOLECULAR-DYNAMICS SIMULATIONS(, BY NMR)
Authors: OOMS F WOUTERS J DURANT F CASTAGNOLI N VANTLAND C DOCKENDOLF G GLASS T VANDERSCHYF CJ
Citation: F. Ooms et al., CONFORMATIONAL DISTRIBUTION OF THE POTENTIALLY NEUROTOXIC METABOLITE OF HALOPERIDOL, HPP-SPECTROSCOPY, X-RAY CRYSTALLOGRAPHY AND MOLECULAR-DYNAMICS SIMULATIONS(, BY NMR), Perkin transactions. 2, (12), 1997, pp. 2627-2632
METABOLIC DEFECTS CAUSED BY TREATMENT WITH THE TETRAHYDROPYRIDINE ANALOG OF HALOPERIDOL (HPTP), IN BABOONS
Authors: MIENIE LJ BERGH JJ VANSTADEN E STEYN SJ POND SM CASTAGNOLI N VANDERSCHYF CJ
Citation: Lj. Mienie et al., METABOLIC DEFECTS CAUSED BY TREATMENT WITH THE TETRAHYDROPYRIDINE ANALOG OF HALOPERIDOL (HPTP), IN BABOONS, Life sciences, 61(3), 1997, pp. 265-272
INHIBITION OF MONOAMINE-OXIDASE CONTRIBUTES TO THE PROTECTIVE EFFECT OF 7-NITROINDAZOLE AGAINST MPTP NEUROTOXICITY
Authors: DIMONTE DA ROYLAND JE ANDERSON A CASTAGNOLI K CASTAGNOLI N LANGSTON JW
Citation: Da. Dimonte et al., INHIBITION OF MONOAMINE-OXIDASE CONTRIBUTES TO THE PROTECTIVE EFFECT OF 7-NITROINDAZOLE AGAINST MPTP NEUROTOXICITY, Journal of neurochemistry, 69(4), 1997, pp. 1771-1773
PROBING THE ACTIVE-SITES OF MONOAMINE-OXIDASE-A AND MONOAMINE-OXIDASE-B WITH 1,4-DISUBSTITUTED TETRAHYDROPYRIDINE SUBSTRATES AND INACTIVATORS
Authors: PALMER SL MABIC S CASTAGNOLI N
Citation: Sl. Palmer et al., PROBING THE ACTIVE-SITES OF MONOAMINE-OXIDASE-A AND MONOAMINE-OXIDASE-B WITH 1,4-DISUBSTITUTED TETRAHYDROPYRIDINE SUBSTRATES AND INACTIVATORS, Journal of medicinal chemistry, 40(13), 1997, pp. 1982-1989
THE EFFECT OF N-METHYLATION ON FENFLURAMINES NEUROTOXIC AND PHARMACOLOGICAL ACTIONS
Authors: FASCIANO J STEELE T CASTAGNOLI N KATZ J RICAURTE G
Citation: J. Fasciano et al., THE EFFECT OF N-METHYLATION ON FENFLURAMINES NEUROTOXIC AND PHARMACOLOGICAL ACTIONS, Brain research, 763(2), 1997, pp. 182-190
EFFECT OF THE HALOPERIDOL TETRAHYDROPYRIDINE METABOLITE UOROPHENYL)-4-OXOBUTYL]-1,2,3,6-TETRAHYDROPYRIDINE ON DOPAMINE-RECEPTOR AND TRANSPORTER BINDING - A NONHUMAN PRIMATE I-123 IODOBENZAMIDE AND 2-BETA-CARBOMETHOXY-3-BETA-(4-IODOPHENYL)TROPANE SINGLE-PHOTON EMISSION COMPUTED TOMOGRAPHIC STUDY
Authors: OLIVER DW DORMEHL IC VANDERSCHYF CJ NEUMEYER JL HUGO N KEEVE R ROSSOUW NT MULLERGARTNER HW CASTAGNOLI N
Citation: Dw. Oliver et al., EFFECT OF THE HALOPERIDOL TETRAHYDROPYRIDINE METABOLITE UOROPHENYL)-4-OXOBUTYL]-1,2,3,6-TETRAHYDROPYRIDINE ON DOPAMINE-RECEPTOR AND TRANSPORTER BINDING - A NONHUMAN PRIMATE I-123 IODOBENZAMIDE AND 2-BETA-CARBOMETHOXY-3-BETA-(4-IODOPHENYL)TROPANE SINGLE-PHOTON EMISSION COMPUTED TOMOGRAPHIC STUDY, Arzneimittel-Forschung, 47(6), 1997, pp. 692-699
SYNTHESIS AND MONOAMINE-OXIDASE-B CATALYZED OXIDATION OF C-4 HETEROAROMATIC SUBSTITUTED 1,2,3,6-TETRAHYDROPYRIDINE DERIVATIVES
Authors: NIMKAR SK ANDERSON AH RIMOLDI JM STANTON M CASTAGNOLI KP MABIC S WANG YX CASTAGNOLI N
Citation: Sk. Nimkar et al., SYNTHESIS AND MONOAMINE-OXIDASE-B CATALYZED OXIDATION OF C-4 HETEROAROMATIC SUBSTITUTED 1,2,3,6-TETRAHYDROPYRIDINE DERIVATIVES, Chemical research in toxicology, 9(6), 1996, pp. 1013-1022
REGIOSELECTIVE SYNTHESIS OF DEUTERATED ANALOGS OF THE NEUROTOXIN MPTP
Authors: MABIC S CASTAGNOLI N
Citation: S. Mabic et N. Castagnoli, REGIOSELECTIVE SYNTHESIS OF DEUTERATED ANALOGS OF THE NEUROTOXIN MPTP, Journal of labelled compounds & radiopharmaceuticals, 38(3), 1996, pp. 255-262
EFFECT OF A PYRIDINIUM METABOLITE DERIVED FROM HALOPERIDOL ON THE ACTIVITIES OF STRIATAL TYROSINE-HYDROXYLASE IN FREELY MOVING RATS
Authors: IGARASHI K MATSUBARA K KASUYA F FUKUI M IDZU T CASTAGNOLI N
Citation: K. Igarashi et al., EFFECT OF A PYRIDINIUM METABOLITE DERIVED FROM HALOPERIDOL ON THE ACTIVITIES OF STRIATAL TYROSINE-HYDROXYLASE IN FREELY MOVING RATS, Neuroscience letters, 214(2-3), 1996, pp. 183-186
LONG-TERM TREATMENT WITH THE TETRAHYDROPYRIDINE ANALOG (HPTP) OF HALOPERIDOL INFLUENCES DOPAMINE LIGAND-BINDING IN BABOON BRAIN - AN [I-123] IODOBENZAMIDE (IBZM) SPECT STUDY
Authors: VANDERSCHYF CJ DORMEHL IC OLIVER DW HUGO N KEEVE R MULLERGARTNER HW POND SM CASTAGNOLI N
Citation: Cj. Vanderschyf et al., LONG-TERM TREATMENT WITH THE TETRAHYDROPYRIDINE ANALOG (HPTP) OF HALOPERIDOL INFLUENCES DOPAMINE LIGAND-BINDING IN BABOON BRAIN - AN [I-123] IODOBENZAMIDE (IBZM) SPECT STUDY, Molecular brain research, 43(1-2), 1996, pp. 251-258
AN MPP(- THE 2() ANALOG )1 N-CYCLOPENTYL-4-PHENYLPYRIDINIUM BROMIDE-4-PHENYLPYRIDINE COMPLEX/
Authors: WOUTERS J EVRARD G DURANT F KALGUTKAR A CASTAGNOLI N
Citation: J. Wouters et al., AN MPP(- THE 2() ANALOG )1 N-CYCLOPENTYL-4-PHENYLPYRIDINIUM BROMIDE-4-PHENYLPYRIDINE COMPLEX/, Acta crystallographica. Section C, Crystal structure communications, 52, 1996, pp. 1033-1036
BIOTRANSFORMATION OF THE MPTP ANALOG THYLAMINOPHENYLETHENYL]-1,2,3,6-TETRAHYDROPYRIDINE TO A FLUORESCENT PYRIDINIUM METABOLITE BY INTACT NEUROBLASTOMA-CELLS
Authors: SONG XO EHRICH M FLAHERTY D WANG YX CASTAGNOLI N
Citation: Xo. Song et al., BIOTRANSFORMATION OF THE MPTP ANALOG THYLAMINOPHENYLETHENYL]-1,2,3,6-TETRAHYDROPYRIDINE TO A FLUORESCENT PYRIDINIUM METABOLITE BY INTACT NEUROBLASTOMA-CELLS, Toxicology and applied pharmacology, 137(2), 1996, pp. 163-172
HALOPERIDOL AND ITS TETRAHYDROPYRIDINE DERIVATIVE (HPTP) ARE METABOLIZED TO POTENTIALLY NEUROTOXIC PYRIDINIUM SPECIES IN THE BABOON
Authors: AVENT KM USUKI E EYLES DW KEEVE R VANDERSCHYF CJ CASTAGNOLI N POND SM
Citation: Km. Avent et al., HALOPERIDOL AND ITS TETRAHYDROPYRIDINE DERIVATIVE (HPTP) ARE METABOLIZED TO POTENTIALLY NEUROTOXIC PYRIDINIUM SPECIES IN THE BABOON, Life sciences, 59(17), 1996, pp. 1473-1482
DOPAMINE-RECEPTOR BINDING OF UOROPHENYL)-4-OXOBUTYL]-1,2,3,6-TETRAHYDROPYRIDINE (HPTP), AN INTERMEDIATE METABOLITE OF HALOPERIDOL
Authors: BRAND L OLIVER DW VANDERSCHYF CJ POND SM CASTAGNOLI N
Citation: L. Brand et al., DOPAMINE-RECEPTOR BINDING OF UOROPHENYL)-4-OXOBUTYL]-1,2,3,6-TETRAHYDROPYRIDINE (HPTP), AN INTERMEDIATE METABOLITE OF HALOPERIDOL, Life sciences, 59(10), 1996, pp. 815-820
SELECTIVE REDUCTIONS OF 1-METHYL-4-PHENYL-2-PYRIDONE
Authors: MABIC S CASTAGNOLI N
Citation: S. Mabic et N. Castagnoli, SELECTIVE REDUCTIONS OF 1-METHYL-4-PHENYL-2-PYRIDONE, Journal of organic chemistry, 61(1), 1996, pp. 309-313
SYNTHESIS AND SELECTIVE MONOAMINE-OXIDASE B-INHIBITING PROPERTIES OF 1-METHYL-1,2,3,6-TETRAHYDROPYRID-4-YL CARBAMATE DERIVATIVES - POTENTIAL PRODRUGS OF (R)-NORDEPRENYL AND (S)-NORDEPRENYL
Authors: FLAHERTY P CASTAGNOLI K WANG YX CASTAGNOLI N
Citation: P. Flaherty et al., SYNTHESIS AND SELECTIVE MONOAMINE-OXIDASE B-INHIBITING PROPERTIES OF 1-METHYL-1,2,3,6-TETRAHYDROPYRID-4-YL CARBAMATE DERIVATIVES - POTENTIAL PRODRUGS OF (R)-NORDEPRENYL AND (S)-NORDEPRENYL, Journal of medicinal chemistry, 39(24), 1996, pp. 4756-4761
ASSESSMENT OF STRUCTURAL REQUIREMENTS FOR THE MONOAMINE OXIDASE-B-CATALYZED OXIDATION OF 1,4-DISUBSTITUTED-1,2,3,6-TETRAHYDROPYRIDINE DERIVATIVES RELATED THE NEUROTOXIN 1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE
Authors: MABIC S CASTAGNOLI N
Citation: S. Mabic et N. Castagnoli, ASSESSMENT OF STRUCTURAL REQUIREMENTS FOR THE MONOAMINE OXIDASE-B-CATALYZED OXIDATION OF 1,4-DISUBSTITUTED-1,2,3,6-TETRAHYDROPYRIDINE DERIVATIVES RELATED THE NEUROTOXIN 1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE, Journal of medicinal chemistry, 39(19), 1996, pp. 3694-3700
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