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Results: 1-13 |
Results: 13
2-PYRIDINYL-3-(4-METHYLSULFONYL)PHENYLPYRIDINES - SELECTIVE AND ORALLY-ACTIVE CYCLOOXYGENASE-2 INHIBITORS
Authors: FRIESEN RW BRIDEAU C CHAN CC CHARLESON S DESCHENES D DUBE D ETHIER D FORTIN R GAUTHIER JY GIRARD Y GORDON R GREIG GM RIENDEAU D SAVOIE C WANG ZY WONG E VISCO D XU LJ YOUNG RN
Citation: Rw. Friesen et al., 2-PYRIDINYL-3-(4-METHYLSULFONYL)PHENYLPYRIDINES - SELECTIVE AND ORALLY-ACTIVE CYCLOOXYGENASE-2 INHIBITORS, Bioorganic & medicinal chemistry letters, 8(19), 1998, pp. 2777-2782
CHARACTERIZATION OF AUTOCRINE INDUCIBLE PROSTAGLANDIN-H SYNTHASE-2 (PGHS-2) IN HUMAN OSTEOSARCOMA CELLS
Authors: WONG E DELUCA C BOILY C CHARLESON S CROMLISH W DENIS D KARGMAN S KENNEDY BP OUELLET M SKOREY K ONEILL GP VICKERS PJ RIENDEAU D
Citation: E. Wong et al., CHARACTERIZATION OF AUTOCRINE INDUCIBLE PROSTAGLANDIN-H SYNTHASE-2 (PGHS-2) IN HUMAN OSTEOSARCOMA CELLS, Inflammation research, 46(2), 1997, pp. 51-59
COMPARISON OF THE CYCLOOXYGENASE-1 INHIBITORY PROPERTIES OF NONSTEROIDAL ANTIINFLAMMATORY DRUGS (NSAIDS) AND SELECTIVE COX-2 INHIBITORS, USING SENSITIVE MICROSOMAL AND PLATELET ASSAYS
Authors: RIENDEAU D CHARLESON S CROMLISH W MANCINI JA WONG E GUAY J
Citation: D. Riendeau et al., COMPARISON OF THE CYCLOOXYGENASE-1 INHIBITORY PROPERTIES OF NONSTEROIDAL ANTIINFLAMMATORY DRUGS (NSAIDS) AND SELECTIVE COX-2 INHIBITORS, USING SENSITIVE MICROSOMAL AND PLATELET ASSAYS, Canadian journal of physiology and pharmacology, 75(9), 1997, pp. 1088-1095
BIOCHEMICAL AND PHARMACOLOGICAL PROFILE OF A TETRASUBSTITUTED FURANONE AS A HIGHLY SELECTIVE COX-2 INHIBITOR
Authors: RIENDEAU D PERCIVAL MD BOYCE S BRIDEAU C CHARLESON S CROMLISH W ETHIER D EVANS J FALGUEYRET JP FORDHUTCHINSON AW GORDON R GREIG G GRESSER M GUAY J KARGMAN S LEGER S MANCINI JA ONEILL G OUELLET M RODGER IW THERIEN M WANG Z WEBB JK WONG E XU L YOUNG RN ZAMBONI R PRASIT P CHAN CC
Citation: D. Riendeau et al., BIOCHEMICAL AND PHARMACOLOGICAL PROFILE OF A TETRASUBSTITUTED FURANONE AS A HIGHLY SELECTIVE COX-2 INHIBITOR, British Journal of Pharmacology, 121(1), 1997, pp. 105-117
FROM INDOMETHACIN TO A SELECTIVE COX-2 INHIBITOR - DEVELOPMENT OF INDOLALKANOIC ACIDS AS POTENT AND SELECTIVE CYCLOOXYGENASE-2 INHIBITORS
Authors: BLACK WC BAYLY C BELLEY M CHAN CC CHARLESON S DENIS D GAUTHIER JY GORDON R GUAY D KARGMAN S LAU CK LEBLANC Y MANCINI J OUELLET M PERCIVAL D ROY P SKOREY K TAGARI P VICKERS P WONG E XU L PRASIT P
Citation: Wc. Black et al., FROM INDOMETHACIN TO A SELECTIVE COX-2 INHIBITOR - DEVELOPMENT OF INDOLALKANOIC ACIDS AS POTENT AND SELECTIVE CYCLOOXYGENASE-2 INHIBITORS, Bioorganic & medicinal chemistry letters, 6(6), 1996, pp. 725-730
SYNTHESIS AND BIOLOGICAL EVALUATION OF BOTH ENANTIOMERS OF L-761,000 AS INHIBITORS OF CYCLOOXYGENASE-1 AND CYCLOOXYGENASE-2
Authors: LEBLANC Y BLACK WC CHAN CC CHARLESON S DELORME D DENIS D GAUTHIER JY GRIMM EL GORDON R GUAY D HAMEL P KARGMAN S LAU CK MANCINI J OUELLET M PERCIVAL D ROY P SKOREY K TAGARI P VICKERS P WONG E XU L PRASTI P
Citation: Y. Leblanc et al., SYNTHESIS AND BIOLOGICAL EVALUATION OF BOTH ENANTIOMERS OF L-761,000 AS INHIBITORS OF CYCLOOXYGENASE-1 AND CYCLOOXYGENASE-2, Bioorganic & medicinal chemistry letters, 6(6), 1996, pp. 731-736
CHARACTERIZATION OF PROSTAGLANDIN G H SYNTHASE-1 AND SYNTHASE-2 IN RAT, DOG, MONKEY, AND HUMAN GASTROINTESTINAL TRACTS/
Authors: KARGMAN S CHARLESON S CARTWRIGHT M FRANK J RIENDEAU D MANCINI J EVANS J ONEILL G
Citation: S. Kargman et al., CHARACTERIZATION OF PROSTAGLANDIN G H SYNTHASE-1 AND SYNTHASE-2 IN RAT, DOG, MONKEY, AND HUMAN GASTROINTESTINAL TRACTS/, Gastroenterology, 111(2), 1996, pp. 445-454
THIOPYRANOL[2,3,4-C,D] INDOLES AS INHIBITORS OF 5-LIPOXYGENASE, 5-LIPOXYGENASE-ACTIVATING PROTEIN, AND LEUKOTRIENE C-4 SYNTHASE
Authors: HUTCHINSON JH CHARLESON S EVANS JF FALGUEYRET JP HOOGSTEEN K JONES TR KARGMAN S MACDONALD D MCFARLANE CS NICHOLSON DW PIECHUTA H RIENDEAU D SCHEIGETZ J THERIEN M GIRARD Y
Citation: Jh. Hutchinson et al., THIOPYRANOL[2,3,4-C,D] INDOLES AS INHIBITORS OF 5-LIPOXYGENASE, 5-LIPOXYGENASE-ACTIVATING PROTEIN, AND LEUKOTRIENE C-4 SYNTHASE, Journal of medicinal chemistry, 38(22), 1995, pp. 4538-4547
STRUCTURAL REQUIREMENTS FOR THE BINDING OF FATTY-ACIDS TO 5-LIPOXYGENASE-ACTIVATING PROTEIN
Authors: CHARLESON S EVANS JF LEGER S PERRIER H PRASIT P WANG ZY VICKERS PJ
Citation: S. Charleson et al., STRUCTURAL REQUIREMENTS FOR THE BINDING OF FATTY-ACIDS TO 5-LIPOXYGENASE-ACTIVATING PROTEIN, European journal of pharmacology. Molecular pharmacology section, 267(3), 1994, pp. 275-280
THE BINDING OF LEUKOTRIENE BIOSYNTHESIS INHIBITORS TO SITE-DIRECTED MUTANTS OF HUMAN 5-LIPOXYGENASE-ACTIVATING PROTEIN
Authors: MANCINI JA COPPOLINO MG KLASSEN JH CHARLESON S VICKERS PJ
Citation: Ja. Mancini et al., THE BINDING OF LEUKOTRIENE BIOSYNTHESIS INHIBITORS TO SITE-DIRECTED MUTANTS OF HUMAN 5-LIPOXYGENASE-ACTIVATING PROTEIN, Life sciences, 54(9), 1994, pp. 137-142
AMINO-ACID-RESIDUES OF 5-LIPOXYGENASE-ACTIVATING PROTEIN CRITICAL FORTHE BINDING OF LEUKOTRIENE BIOSYNTHESIS INHIBITORS
Authors: VICKERS PJ ADAM M CHARLESON S ABRAMOVITZ M ONEILL G MANCINI JA
Citation: Pj. Vickers et al., AMINO-ACID-RESIDUES OF 5-LIPOXYGENASE-ACTIVATING PROTEIN CRITICAL FORTHE BINDING OF LEUKOTRIENE BIOSYNTHESIS INHIBITORS, Journal of lipid mediators, 6(1-3), 1993, pp. 31-42
A NEW CLASS OF LEUKOTRIENE BIOSYNTHESIS INHIBITOR - THE DEVELOPMENT OF MK-0591
Authors: PRASIT P BELLEY M BLOUIN M BRIDEAU C CHAN C CHARLESON S EVANS JF FRENETTE R GAUTHIER JY GUAY J GILLARD JW GRIMM E FORDHUTCHINSON AW HUTCHINSON JH FORTIN R JONES TR MANCINI J LEGER S MCFARLANE CS PIECHUTA H RIENDEAU D ROY P TAGARI P VICKERS PJ YOUNG RN ZAMBONI R
Citation: P. Prasit et al., A NEW CLASS OF LEUKOTRIENE BIOSYNTHESIS INHIBITOR - THE DEVELOPMENT OF MK-0591, Journal of lipid mediators, 6(1-3), 1993, pp. 239-244
5-LIPOXYGENASE AND 5-LIPOXYGENASE ACTIVATING PROTEIN ARE LOCALIZED INTHE NUCLEAR-ENVELOPE OF ACTIVATED HUMAN-LEUKOCYTES
Authors: WOODS JW EVANS JF ETHIER D SCOTT S VICKERS PJ HEARN L HEIBEIN JA CHARLESON S SINGER II
Citation: Jw. Woods et al., 5-LIPOXYGENASE AND 5-LIPOXYGENASE ACTIVATING PROTEIN ARE LOCALIZED INTHE NUCLEAR-ENVELOPE OF ACTIVATED HUMAN-LEUKOCYTES, The Journal of experimental medicine, 178(6), 1993, pp. 1935-1946
Risultati: 1-13 |