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Results: 1-11 |
Results: 11
DIBASIC BENZO[B]THIOPHENE DERIVATIVES AS A NOVEL CLASS OF ACTIVE-SITE-DIRECTED THROMBIN INHIBITORS - 2 - EXPLORING INTERACTIONS AT THE PROXIMAL (S-2) BINDING-SITE
Authors: SALL DJ BRIGGS SL CHIRGADZE NY CLAWSON DK GIFFORDMOORE DS KLIMKOWSKI VJ MCCOWAN JR SMITH GF WIKEL JH
Citation: Dj. Sall et al., DIBASIC BENZO[B]THIOPHENE DERIVATIVES AS A NOVEL CLASS OF ACTIVE-SITE-DIRECTED THROMBIN INHIBITORS - 2 - EXPLORING INTERACTIONS AT THE PROXIMAL (S-2) BINDING-SITE, Bioorganic & medicinal chemistry letters, 8(18), 1998, pp. 2527-2532
THE CRYSTAL-STRUCTURE OF HUMAN ALPHA-THROMBIN COMPLEXED WITH LY178550, A NONPEPTIDYL, ACTIVE-SITE-DIRECTED INHIBITOR
Authors: CHIRGADZE NY SALL DJ KLIMKOWSKI VJ CLAWSON DK BRIGGS SL HERMANN R SMITH GF GIFFORDMOORE DS WERY JP
Citation: Ny. Chirgadze et al., THE CRYSTAL-STRUCTURE OF HUMAN ALPHA-THROMBIN COMPLEXED WITH LY178550, A NONPEPTIDYL, ACTIVE-SITE-DIRECTED INHIBITOR, Protein science, 6(7), 1997, pp. 1412-1417
A SINGLE SEQUENCE CHANGE DESTABILIZES THE INFLUENZA-VIRUS NEURAMINIDASE TETRAMER
Authors: COLACINO JM CHIRGADZE NY GARMAN E MURTI KG LONCHARICH RJ BAXTER AJ STASCHKE KA LAVER WG
Citation: Jm. Colacino et al., A SINGLE SEQUENCE CHANGE DESTABILIZES THE INFLUENZA-VIRUS NEURAMINIDASE TETRAMER, Virology, 236(1), 1997, pp. 66-75
VIRACEPT (NELFINAVIR MESYLATE, AG1343) - A POTENT, ORALLY BIOAVAILABLE INHIBITOR OF HIV-1 PROTEASE
Authors: KALDOR SW KALISH VJ DAVIES JF SHETTY BV FRITZ JE APPELT K BURGESS JA CAMPANALE KM CHIRGADZE NY CLAWSON DK DRESSMAN BA HATCH SD KHALIL DA KOSA MB LUBBEHUSEN PP MUESING MA PATICK AK REICH SH SU KS TATLOCK JH
Citation: Sw. Kaldor et al., VIRACEPT (NELFINAVIR MESYLATE, AG1343) - A POTENT, ORALLY BIOAVAILABLE INHIBITOR OF HIV-1 PROTEASE, Journal of medicinal chemistry, 40(24), 1997, pp. 3979-3985
DIBASIC BENZO[B]THIOPHENE DERIVATIVES AS A NOVEL CLASS OF ACTIVE-SITE-DIRECTED THROMBIN INHIBITORS .1. DETERMINATION OF THE SERINE-PROTEASESELECTIVITY, STRUCTURE-ACTIVITY-RELATIONSHIPS, AND BINDING ORIENTATION
Authors: SALL DJ BASTIAN JA BRIGGS SL BUBEN JA CHIRGADZE NY CLAWSON DK DENNEY ML GIERA DD GIFFORDMOORE DS HARPER RW HAUSER KL KLIMKOWSKI VJ KOHN TJ LIN HS MCCOWAN JR PALKOWITZ AD SMITH GF TAKEUCHI K THRASHER KJ TINSLEY JM UTTERBACK BG YAN SCB ZHANG MS
Citation: Dj. Sall et al., DIBASIC BENZO[B]THIOPHENE DERIVATIVES AS A NOVEL CLASS OF ACTIVE-SITE-DIRECTED THROMBIN INHIBITORS .1. DETERMINATION OF THE SERINE-PROTEASESELECTIVITY, STRUCTURE-ACTIVITY-RELATIONSHIPS, AND BINDING ORIENTATION, Journal of medicinal chemistry, 40(22), 1997, pp. 3489-3493
D-PHE-PRO-P-AMIDINOBENZYLAMINE - A POTENT AND HIGHLY SELECTIVE THROMBIN INHIBITOR
Authors: WILEY MR CHIRGADZE NY CLAWSON DK CRAFT TJ GIFFORDMOORE DS JONES ND OLKOWSKI JL WEIR LC SMITH GF
Citation: Mr. Wiley et al., D-PHE-PRO-P-AMIDINOBENZYLAMINE - A POTENT AND HIGHLY SELECTIVE THROMBIN INHIBITOR, Bioorganic & medicinal chemistry letters, 6(20), 1996, pp. 2387-2392
INDOLE INHIBITORS OF HUMAN NONPANCREATIC SECRETORY PHOSPHOLIPASE A(2).1. INDOLE-3-ACETAMIDES
Authors: DILLARD RD BACH NJ DRAHEIM SE BERRY DR CARLSON DG CHIRGADZE NY CLAWSON DK HARTLEY LW JOHNSON LM JONES ND MCKINNEY ER MIHELICH ED OLKOWSKI JL SCHEVITZ RW SMITH AC SNYDER DW SOMMERS CD WERY JP
Citation: Rd. Dillard et al., INDOLE INHIBITORS OF HUMAN NONPANCREATIC SECRETORY PHOSPHOLIPASE A(2).1. INDOLE-3-ACETAMIDES, Journal of medicinal chemistry, 39(26), 1996, pp. 5119-5136
INDOLE INHIBITORS OF HUMAN NONPANCREATIC SECRETORY PHOSPHOLIPASE A(2).2. INDOLE-3-ACETAMIDES WITH ADDITIONAL FUNCTIONALITY
Authors: DILLARD RD BACH NJ DRAHEIM SE BERRY DR CARLSON DG CHIRGADZE NY CLAWSON DK HARTLEY LW JOHNSON LM JONES ND MCKINNEY ER MIHELICH ED OLKOWSKI JL SCHEVITZ RW SMITH AC SNYDER DW SOMMERS CD WERY JP
Citation: Rd. Dillard et al., INDOLE INHIBITORS OF HUMAN NONPANCREATIC SECRETORY PHOSPHOLIPASE A(2).2. INDOLE-3-ACETAMIDES WITH ADDITIONAL FUNCTIONALITY, Journal of medicinal chemistry, 39(26), 1996, pp. 5137-5158
INDOLE INHIBITORS OF HUMAN NONPANCREATIC SECRETORY PHOSPHOLIPASE A(2).3. INDOLE-3-GLYOXAMIDES
Authors: DRAHEIM SE BACH NJ DILLARD RD BERRY DR CARLSON DG CHIRGADZE NY CLAWSON DK HARTLEY LW JOHNSON LM JONES ND MCKINNEY ER MIHELICH ED OLKOWSKI JL SCHEVITZ RW SMITH AC SNYDER DW SOMMERS CD WERY JP
Citation: Se. Draheim et al., INDOLE INHIBITORS OF HUMAN NONPANCREATIC SECRETORY PHOSPHOLIPASE A(2).3. INDOLE-3-GLYOXAMIDES, Journal of medicinal chemistry, 39(26), 1996, pp. 5159-5175
STRUCTURE-BASED DESIGN OF THE FIRST POTENT AND SELECTIVE INHIBITOR OFHUMAN NONPANCREATIC SECRETORY PHOSPHOLIPASE-A(2)
Authors: SCHEVITZ RW BACH NJ CARLSON DG CHIRGADZE NY CLAWSON DK DILLARD RD DRAHEIM SE HARTLEY LW JONES ND MIHELICH ED OLKOWSKI JL SNYDER DW SOMMERS C WERY JP
Citation: Rw. Schevitz et al., STRUCTURE-BASED DESIGN OF THE FIRST POTENT AND SELECTIVE INHIBITOR OFHUMAN NONPANCREATIC SECRETORY PHOSPHOLIPASE-A(2), Nature structural biology, 2(6), 1995, pp. 458-465
SERINE-PROTEASE SELECTIVITY OF THE THROMBIN INHIBITOR D-PHE-PRO-AGMATINE AND ITS HOMOLOGS
Authors: WILEY MR CHIRGADZE NY CLAWSON DK CRAFT TJ GIFFORDMOORE DS JONES ND OLKOWSKI JL SCHACHT AL WEIR LC SMITH GF
Citation: Mr. Wiley et al., SERINE-PROTEASE SELECTIVITY OF THE THROMBIN INHIBITOR D-PHE-PRO-AGMATINE AND ITS HOMOLOGS, Bioorganic & medicinal chemistry letters, 5(23), 1995, pp. 2835-2840
Risultati: 1-11 |