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Results: 1-25 | 26-46
Results: 1-25/46
MOLECULAR-BASIS OF HYPERARGININEMIA - STRUCTURE-FUNCTION CONSEQUENCESOF MUTATIONS IN HUMAN LIVER ARGINASE
Authors: ASH DE SCOLNICK LR KANYO ZF VOCKLEY JG CEDERBAUM SD CHRISTIANSON DW
Citation: De. Ash et al., MOLECULAR-BASIS OF HYPERARGININEMIA - STRUCTURE-FUNCTION CONSEQUENCESOF MUTATIONS IN HUMAN LIVER ARGINASE, MOLECULAR GENETICS AND METABOLISM, 64(4), 1998, pp. 243-249
STRUCTURES OF MURINE CARBONIC-ANHYDRASE-IV AND HUMAN CARBONIC-ANHYDRASE-II COMPLEXED WITH BRINZOLAMIDE - MOLECULAR-BASIS OF ISOZYME-DRUG DISCRIMINATION
Authors: STAMS T CHEN Y BORIACKSJODIN PA HURT JD LIAO J MAY JA DEAN T LAIPIS P SILVERMAN DN CHRISTIANSON DW
Citation: T. Stams et al., STRUCTURES OF MURINE CARBONIC-ANHYDRASE-IV AND HUMAN CARBONIC-ANHYDRASE-II COMPLEXED WITH BRINZOLAMIDE - MOLECULAR-BASIS OF ISOZYME-DRUG DISCRIMINATION, Protein science, 7(3), 1998, pp. 556-563
RIBONUCLEASE-P PROTEIN-STRUCTURE - EVOLUTIONARY ORIGINS IN THE TRANSLATIONAL APPARATUS
Authors: STAMS T NIRANJANAKUMARI S FIERKE CA CHRISTIANSON DW
Citation: T. Stams et al., RIBONUCLEASE-P PROTEIN-STRUCTURE - EVOLUTIONARY ORIGINS IN THE TRANSLATIONAL APPARATUS, Science, 280(5364), 1998, pp. 752-755
ENGINEERING AN ANION-BINDING CAVITY IN ANTICHYMOTRYPSIN MODULATES THESPRING-LOADED SERPIN-PROTEASE INTERACTION
Authors: LUKACS CM RUBIN H CHRISTIANSON DW
Citation: Cm. Lukacs et al., ENGINEERING AN ANION-BINDING CAVITY IN ANTICHYMOTRYPSIN MODULATES THESPRING-LOADED SERPIN-PROTEASE INTERACTION, Biochemistry, 37(10), 1998, pp. 3297-3304
STRUCTURAL CHEMISTRY AND BIOLOGY OF MANGANESE METALLOENZYMES
Authors: CHRISTIANSON DW
Citation: Dw. Christianson, STRUCTURAL CHEMISTRY AND BIOLOGY OF MANGANESE METALLOENZYMES, Progress in Biophysics and Molecular Biology, 67(2-3), 1997, pp. 217
CRYSTAL-STRUCTURE OF PENTALENENE SYNTHASE - MECHANISTIC INSIGHTS ON TERPENOID CYCLIZATION REACTIONS IN BIOLOGY
Authors: LESBURG CA ZHAI GZ CANE DE CHRISTIANSON DW
Citation: Ca. Lesburg et al., CRYSTAL-STRUCTURE OF PENTALENENE SYNTHASE - MECHANISTIC INSIGHTS ON TERPENOID CYCLIZATION REACTIONS IN BIOLOGY, Science, 277(5333), 1997, pp. 1820-1824
HISTIDINE-]CARBOXAMIDE LIGAND SUBSTITUTIONS IN THE ZINC-BINDING SITE OF CARBONIC-ANHYDRASE-II ALTER METAL COORDINATION GEOMETRY BUT RETAIN CATALYTIC ACTIVITY
Authors: LESBURG CA HUANG CC CHRISTIANSON DW FIERKE CA
Citation: Ca. Lesburg et al., HISTIDINE-]CARBOXAMIDE LIGAND SUBSTITUTIONS IN THE ZINC-BINDING SITE OF CARBONIC-ANHYDRASE-II ALTER METAL COORDINATION GEOMETRY BUT RETAIN CATALYTIC ACTIVITY, Biochemistry, 36(50), 1997, pp. 15780-15791
ALTERING THE BINUCLEAR MANGANESE CLUSTER OF ARGINASE DIMINISHES THERMOSTABILITY AND CATALYTIC FUNCTION
Authors: SCOLNICK LR KANYO ZF CAVALLI RC ASH DE CHRISTIANSON DW
Citation: Lr. Scolnick et al., ALTERING THE BINUCLEAR MANGANESE CLUSTER OF ARGINASE DIMINISHES THERMOSTABILITY AND CATALYTIC FUNCTION, Biochemistry, 36(34), 1997, pp. 10558-10565
NOVEL BINDING MODE OF HYDROXAMATE INHIBITORS TO HUMAN CARBONIC-ANHYDRASE-II
Authors: SCOLNICK LR CLEMENTS AM LIAO J CRENSHAW L HELLBERG M MAY J DEAN TR CHRISTIANSON DW
Citation: Lr. Scolnick et al., NOVEL BINDING MODE OF HYDROXAMATE INHIBITORS TO HUMAN CARBONIC-ANHYDRASE-II, Journal of the American Chemical Society, 119(4), 1997, pp. 850-851
INHIBITION OF MN-2(2-ARGINASE BY BORATE LEADS TO THE DESIGN OF A TRANSITION-STATE ANALOG INHIBITOR, 2(S)-AMINO-6-BORONOHEXANOIC ACID())
Authors: BAGGIO R ELBAUM D KANYO ZF CARROLL PJ CAVALLI RC ASH DE CHRISTIANSON DW
Citation: R. Baggio et al., INHIBITION OF MN-2(2-ARGINASE BY BORATE LEADS TO THE DESIGN OF A TRANSITION-STATE ANALOG INHIBITOR, 2(S)-AMINO-6-BORONOHEXANOIC ACID()), Journal of the American Chemical Society, 119(34), 1997, pp. 8107-8108
ARGININE SUBSTITUTIONS IN THE HINGE REGION OF ANTICHYMOTRYPSIN AFFECTSERPIN BETA-SHEET REARRANGEMENT
Authors: LUKACS CM ZHONG JQ PLOTNICK MI RUBIN H COOPERMAN BS CHRISTIANSON DW
Citation: Cm. Lukacs et al., ARGININE SUBSTITUTIONS IN THE HINGE REGION OF ANTICHYMOTRYPSIN AFFECTSERPIN BETA-SHEET REARRANGEMENT, Nature structural biology, 3(10), 1996, pp. 888-893
IS THE BINDING OF BETA-AMYLOID PROTEIN TO ANTICHYMOTRYPSIN IN ALZHEIMER PLAQUES MEDIATED BY A BETA-STRAND INSERTION
Authors: LUKACS CM CHRISTIANSON DW
Citation: Cm. Lukacs et Dw. Christianson, IS THE BINDING OF BETA-AMYLOID PROTEIN TO ANTICHYMOTRYPSIN IN ALZHEIMER PLAQUES MEDIATED BY A BETA-STRAND INSERTION, Proteins, 25(4), 1996, pp. 420-424
STRUCTURE OF A UNIQUE BINUCLEAR MANGANESE CLUSTER IN ARGINASE
Authors: KANYO ZF SCOLNICK LR ASH DE CHRISTIANSON DW
Citation: Zf. Kanyo et al., STRUCTURE OF A UNIQUE BINUCLEAR MANGANESE CLUSTER IN ARGINASE, Nature, 383(6600), 1996, pp. 554-557
CRYSTAL-STRUCTURE OF THE SECRETORY FORM OF MEMBRANE-ASSOCIATED HUMAN CARBONIC-ANHYDRASE-IV AT 2.8-ANGSTROM RESOLUTION
Authors: STAMS T NAIR SK OKUYAMA T WAHEED A SLY WS CHRISTIANSON DW
Citation: T. Stams et al., CRYSTAL-STRUCTURE OF THE SECRETORY FORM OF MEMBRANE-ASSOCIATED HUMAN CARBONIC-ANHYDRASE-IV AT 2.8-ANGSTROM RESOLUTION, Proceedings of the National Academy of Sciences of the United Statesof America, 93(24), 1996, pp. 13589-13594
UNEXPECTED BINDING MODE OF THE SULFONAMIDE FLUOROPHORE 5-DIMETHYLAMINO-1-NAPHTHALENE SULFONAMIDE TO HUMAN CARBONIC-ANHYDRASE-II - IMPLICATIONS FOR THE DEVELOPMENT OF A ZINC BIOSENSOR
Authors: NAIR SK ELBAUM D CHRISTIANSON DW
Citation: Sk. Nair et al., UNEXPECTED BINDING MODE OF THE SULFONAMIDE FLUOROPHORE 5-DIMETHYLAMINO-1-NAPHTHALENE SULFONAMIDE TO HUMAN CARBONIC-ANHYDRASE-II - IMPLICATIONS FOR THE DEVELOPMENT OF A ZINC BIOSENSOR, The Journal of biological chemistry, 271(2), 1996, pp. 1003-1007
X-RAY CRYSTALLOGRAPHIC STUDIES OF ALANINE-65 VARIANTS OF CARBONIC-ANHYDRASE-II REVEAL THE STRUCTURAL BASIS OF COMPROMISED PROTON-TRANSFER IN CATALYSIS
Authors: SCOLNICK LR CHRISTIANSON DW
Citation: Lr. Scolnick et Dw. Christianson, X-RAY CRYSTALLOGRAPHIC STUDIES OF ALANINE-65 VARIANTS OF CARBONIC-ANHYDRASE-II REVEAL THE STRUCTURAL BASIS OF COMPROMISED PROTON-TRANSFER IN CATALYSIS, Biochemistry, 35(51), 1996, pp. 16429-16434
STRUCTURE-BASED DESIGN OF AN INTRAMOLECULAR PROTON-TRANSFER SITE IN MURINE CARBONIC-ANHYDRASE-V
Authors: HECK RW BORIACKSJODIN PA QIAN MZ TU CK CHRISTIANSON DW LAIPIS PJ SILVERMAN DN
Citation: Rw. Heck et al., STRUCTURE-BASED DESIGN OF AN INTRAMOLECULAR PROTON-TRANSFER SITE IN MURINE CARBONIC-ANHYDRASE-V, Biochemistry, 35(36), 1996, pp. 11605-11611
STRUCTURAL-CHANGE IN ALPHA-CHYMOTRYPSIN INDUCED BY COMPLEXATION WITH ALPHA(1)-ANTICHYMOTRYPSIN AS SEEN BY ENHANCED SENSITIVITY TO PROTEOLYSIS
Authors: STAVRIDI ES OMALLEY K LUKACS CM MOORE WT LAMBRIS JD CHRISTIANSON DW RUBIN H COOPERMAN BS
Citation: Es. Stavridi et al., STRUCTURAL-CHANGE IN ALPHA-CHYMOTRYPSIN INDUCED BY COMPLEXATION WITH ALPHA(1)-ANTICHYMOTRYPSIN AS SEEN BY ENHANCED SENSITIVITY TO PROTEOLYSIS, Biochemistry, 35(33), 1996, pp. 10608-10615
REDESIGN OF THE ZINC-BINDING SITE IN CARBONIC-ANHYDRASE
Authors: FIERKE CA CHRISTIANSON DW
Citation: Ca. Fierke et Dw. Christianson, REDESIGN OF THE ZINC-BINDING SITE IN CARBONIC-ANHYDRASE, Biochemistry, 35(28), 1996, pp. 2-2
REVERSAL OF THE HYDROGEN-BOND TO ZINC LIGAND HISTIDINE-119 DRAMATICALLY DIMINISHES CATALYSIS AND ENHANCES METAL EQUILIBRATION KINETICS IN CARBONIC-ANHYDRASE-II
Authors: HUANG CC LESBURG CA KIEFER LL FIERKE CA CHRISTIANSON DW
Citation: Cc. Huang et al., REVERSAL OF THE HYDROGEN-BOND TO ZINC LIGAND HISTIDINE-119 DRAMATICALLY DIMINISHES CATALYSIS AND ENHANCES METAL EQUILIBRATION KINETICS IN CARBONIC-ANHYDRASE-II, Biochemistry, 35(11), 1996, pp. 3439-3446
STRUCTURE-BASED DESIGN OF A SULFONAMIDE PROBE FOR FLUORESCENCE ANISOTROPY DETECTION OF ZINC WITH A CARBONIC ANHYDRASE-BASED BIOSENSOR
Authors: ELBAUM D NAIR SK PATCHAN MW THOMPSON RB CHRISTIANSON DW
Citation: D. Elbaum et al., STRUCTURE-BASED DESIGN OF A SULFONAMIDE PROBE FOR FLUORESCENCE ANISOTROPY DETECTION OF ZINC WITH A CARBONIC ANHYDRASE-BASED BIOSENSOR, Journal of the American Chemical Society, 118(35), 1996, pp. 8381-8387
CARBONIC-ANHYDRASE - EVOLUTION OF THE ZINC-BINDING SITE BY NATURE ANDBY DESIGN
Authors: CHRISTIANSON DW FIERKE CA
Citation: Dw. Christianson et Ca. Fierke, CARBONIC-ANHYDRASE - EVOLUTION OF THE ZINC-BINDING SITE BY NATURE ANDBY DESIGN, Accounts of chemical research, 29(7), 1996, pp. 331-339
CRYSTALLIZATION AND PRELIMINARY-X-RAY DIFFRACTION ANALYSIS OF RECOMBINANT PENTALENENE SYNTHASE
Authors: LESBURG CA LLOYD MD CANE DE CHRISTIANSON DW
Citation: Ca. Lesburg et al., CRYSTALLIZATION AND PRELIMINARY-X-RAY DIFFRACTION ANALYSIS OF RECOMBINANT PENTALENENE SYNTHASE, Protein science, 4(11), 1995, pp. 2436-2438
STRUCTURE OF HIS94-]ASP CARBONIC-ANHYDRASE-II IN A NEW CRYSTALLINE FORM REVEALS A PARTIALLY OCCUPIED ZINC-BINDING SITE
Authors: IPPOLITO JA NAIR SK ALEXANDER RS KIEFER LL FIERKE CA CHRISTIANSON DW
Citation: Ja. Ippolito et al., STRUCTURE OF HIS94-]ASP CARBONIC-ANHYDRASE-II IN A NEW CRYSTALLINE FORM REVEALS A PARTIALLY OCCUPIED ZINC-BINDING SITE, Protein engineering, 8(10), 1995, pp. 975-980
STRUCTURE DETERMINATION OF MURINE MITOCHONDRIAL CARBONIC-ANHYDRASE-V AT 2.45-ANGSTROM RESOLUTION - IMPLICATIONS FOR CATALYTIC PROTON-TRANSFER AND INHIBITOR DESIGN
Authors: BORIACKSJODIN PA HECK RW LAIPIS PJ SILVERMAN DN CHRISTIANSON DW
Citation: Pa. Boriacksjodin et al., STRUCTURE DETERMINATION OF MURINE MITOCHONDRIAL CARBONIC-ANHYDRASE-V AT 2.45-ANGSTROM RESOLUTION - IMPLICATIONS FOR CATALYTIC PROTON-TRANSFER AND INHIBITOR DESIGN, Proceedings of the National Academy of Sciences of the United Statesof America, 92(24), 1995, pp. 10949-10953
Risultati: 1-25 | 26-46