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Results: 1-14 |
Results: 14
COMMENTARY ON INTEGRATION OF IN-VITRO DATA AND BRAIN-WEIGHT IN ALLOMETRIC SCALING TO PREDICT CLEARANCE IN HUMANS - SOME SUGGESTIONS
Authors: LAVE T COASSOLO P
Citation: T. Lave et P. Coassolo, COMMENTARY ON INTEGRATION OF IN-VITRO DATA AND BRAIN-WEIGHT IN ALLOMETRIC SCALING TO PREDICT CLEARANCE IN HUMANS - SOME SUGGESTIONS, Journal of pharmaceutical sciences, 87(4), 1998, pp. 530-530
THE USE OF HUMAN HEPATOCYTES TO SELECT COMPOUNDS BASED ON THEIR EXPECTED HEPATIC EXTRACTION RATIOS IN HUMANS
Authors: LAVE T DUPIN S SCHMITT C VALLES B UBEAUD G CHOU RC JAECK D COASSOLO P
Citation: T. Lave et al., THE USE OF HUMAN HEPATOCYTES TO SELECT COMPOUNDS BASED ON THEIR EXPECTED HEPATIC EXTRACTION RATIOS IN HUMANS, Pharmaceutical research, 14(2), 1997, pp. 152-155
RO-61-1790, A NEW HYDROSOLUBLE ENDOTHELIN ANTAGONIST - GENERAL PHARMACOLOGY AND EFFECTS ON EXPERIMENTAL CEREBRAL VASOSPASM
Authors: ROUX S BREU V GILLER T NEIDHART W RAMUZ H COASSOLO P CLOZEL JP CLOZEL M
Citation: S. Roux et al., RO-61-1790, A NEW HYDROSOLUBLE ENDOTHELIN ANTAGONIST - GENERAL PHARMACOLOGY AND EFFECTS ON EXPERIMENTAL CEREBRAL VASOSPASM, The Journal of pharmacology and experimental therapeutics, 283(3), 1997, pp. 1110-1118
INTEGRATION OF IN-VITRO DATA INTO ALLOMETRIC SCALING TO PREDICT HEPATIC METABOLIC-CLEARANCE IN MAN - APPLICATION TO 10 EXTENSIVELY METABOLIZED DRUGS
Authors: LAVE T DUPIN S SCHMITT C CHOU RC JAECK D COASSOLO P
Citation: T. Lave et al., INTEGRATION OF IN-VITRO DATA INTO ALLOMETRIC SCALING TO PREDICT HEPATIC METABOLIC-CLEARANCE IN MAN - APPLICATION TO 10 EXTENSIVELY METABOLIZED DRUGS, Journal of pharmaceutical sciences, 86(5), 1997, pp. 584-590
INTERSPECIES SCALING OF BOSENTAN, A NEW ENDOTHELIN RECEPTOR ANTAGONIST AND INTEGRATION OF IN-VITRO DATA INTO ALLOMETRIC SCALING
Authors: LAVE T COASSOLO P UBEAUD G BRANDT R SCHMITT C DUPIN S JAECK D CHOU RC
Citation: T. Lave et al., INTERSPECIES SCALING OF BOSENTAN, A NEW ENDOTHELIN RECEPTOR ANTAGONIST AND INTEGRATION OF IN-VITRO DATA INTO ALLOMETRIC SCALING, Pharmaceutical research, 13(1), 1996, pp. 97-101
INTERSPECIES SCALING OF TOLCAPONE, A NEW INHIBITOR OF CATECHOL-O-METHYLTRANSFERASE (COMT) - USE OF IN-VITRO DATA FROM HEPATOCYTES TO PREDICT METABOLIC-CLEARANCE IN ANIMALS AND HUMANS
Authors: LAVE T DUPIN S SCHMITT M KAPPS M MEYER J MORGENROTH B CHOU RC JAECK D COASSOLO P
Citation: T. Lave et al., INTERSPECIES SCALING OF TOLCAPONE, A NEW INHIBITOR OF CATECHOL-O-METHYLTRANSFERASE (COMT) - USE OF IN-VITRO DATA FROM HEPATOCYTES TO PREDICT METABOLIC-CLEARANCE IN ANIMALS AND HUMANS, Xenobiotica, 26(8), 1996, pp. 839-851
PHARMACOKINETICS OF REMIKIREN, A POTENT ORALLY-ACTIVE INHIBITOR OF HUMAN RENIN, IN RAT, DOG AND PRIMATES
Authors: COASSOLO P FISCHLI W CLOZEL JP CHOU RC
Citation: P. Coassolo et al., PHARMACOKINETICS OF REMIKIREN, A POTENT ORALLY-ACTIVE INHIBITOR OF HUMAN RENIN, IN RAT, DOG AND PRIMATES, Xenobiotica, 26(3), 1996, pp. 333-345
ANIMAL PHARMACOKINETICS AND INTERSPECIES SCALING FROM ANIMALS TO MAN OF LAMIFIBAN, A NEW PLATELET-AGGREGATION INHIBITOR
Authors: LAVE T SANER A COASSOLO P BRANDT R SCHMITTHOFFMANN AH CHOU RC
Citation: T. Lave et al., ANIMAL PHARMACOKINETICS AND INTERSPECIES SCALING FROM ANIMALS TO MAN OF LAMIFIBAN, A NEW PLATELET-AGGREGATION INHIBITOR, Journal of Pharmacy and Pharmacology, 48(6), 1996, pp. 573-577
RELATIONSHIPS BETWEEN IN-VITRO AND IN-VIVO BIOTRANSFORMATION OF DRUGSIN HUMANS AND ANIMALS - PHARMACOTOXICOLOGICAL CONSEQUENCES
Authors: DESOUSA G FLORENCE N VALLES B COASSOLO P RAHMANI R
Citation: G. Desousa et al., RELATIONSHIPS BETWEEN IN-VITRO AND IN-VIVO BIOTRANSFORMATION OF DRUGSIN HUMANS AND ANIMALS - PHARMACOTOXICOLOGICAL CONSEQUENCES, Cell biology and toxicology, 11(3-4), 1995, pp. 147-153
IN-VIVO AND IN-VITRO KINETICS OF MOFAROTENE IN MOUSE, RAT, DOG AND MAN
Authors: VALLES B BA B WYSS R REIGNER B COASSOLO P
Citation: B. Valles et al., IN-VIVO AND IN-VITRO KINETICS OF MOFAROTENE IN MOUSE, RAT, DOG AND MAN, European journal of drug metabolism and pharmacokinetics, 20(1), 1995, pp. 49-53
METABOLISM OF MOFAROTENE IN HEPATOCYTES AND LIVER-MICROSOMES FROM DIFFERENT SPECIES - COMPARISON WITH IN-VIVO DATA AND EVALUATION OF THE CYTOCHROME-P450 ISOENZYMES INVOLVED IN HUMAN BIOTRANSFORMATION
Authors: VALLES B SCHILLER CD COASSOLO P DESOUSA G WYSS R JAECK D VIGERCHOUGNET A RAHMANI R
Citation: B. Valles et al., METABOLISM OF MOFAROTENE IN HEPATOCYTES AND LIVER-MICROSOMES FROM DIFFERENT SPECIES - COMPARISON WITH IN-VIVO DATA AND EVALUATION OF THE CYTOCHROME-P450 ISOENZYMES INVOLVED IN HUMAN BIOTRANSFORMATION, Drug metabolism and disposition, 23(10), 1995, pp. 1051-1057
BOSENTAN, A NEW ENDOTHELIN RECEPTOR ANTAGONIST - PREDICTION OF THE SYSTEMIC PLASMA-CLEARANCE IN MAN FROM COMBINED IN-VIVO AND IN-VITRO DATA
Authors: UBEAUD G SCHMITT C JAECK D LAVE T COASSOLO P
Citation: G. Ubeaud et al., BOSENTAN, A NEW ENDOTHELIN RECEPTOR ANTAGONIST - PREDICTION OF THE SYSTEMIC PLASMA-CLEARANCE IN MAN FROM COMBINED IN-VIVO AND IN-VITRO DATA, Xenobiotica, 25(12), 1995, pp. 1381-1390
A NEW EXTRAPOLATION METHOD FROM ANIMALS TO MAN - APPLICATION TO A METABOLIZED COMPOUND, MOFAROTENE
Authors: LAVE T SCHMITTHOFFMANN AH COASSOLO P VALLES B UBEAUD G BA B BRANDT R CHOU RC
Citation: T. Lave et al., A NEW EXTRAPOLATION METHOD FROM ANIMALS TO MAN - APPLICATION TO A METABOLIZED COMPOUND, MOFAROTENE, Life sciences, 56(26), 1995, pp. 473-478
IN-VITRO HEPATIC BIOTRANSFORMATION OF MOCLOBEMIDE (RO 11-1163) IN MANAND RAT
Authors: VALLES B COASSOLO P DESOUSA G AUBERT C RAHMANI R
Citation: B. Valles et al., IN-VITRO HEPATIC BIOTRANSFORMATION OF MOCLOBEMIDE (RO 11-1163) IN MANAND RAT, Xenobiotica, 23(10), 1993, pp. 1101-1111
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