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Results: 1-16 |
Results: 16
PULMONARY BIOAVAILABILITY OF A PHOSPHOROTHIOATE OLIGONUCLEOTIDE (CGP 64128A) - COMPARISON WITH OTHER DELIVERY ROUTES
Authors: NICKLIN PL BAYLEY D GIDDINGS J CRAIG SJ CUMMINS LL HASTEWELL JG PHILLIPS JA
Citation: Pl. Nicklin et al., PULMONARY BIOAVAILABILITY OF A PHOSPHOROTHIOATE OLIGONUCLEOTIDE (CGP 64128A) - COMPARISON WITH OTHER DELIVERY ROUTES, Pharmaceutical research, 15(4), 1998, pp. 583-591
RAPID DECONVOLUTION OF COMBINATORIAL LIBRARIES USING HPLC FRACTIONATION
Authors: GRIFFEY RH AN HY CUMMINS LL GAUS HJ HALY B HERRMANN R COOK PD
Citation: Rh. Griffey et al., RAPID DECONVOLUTION OF COMBINATORIAL LIBRARIES USING HPLC FRACTIONATION, Tetrahedron, 54(16), 1998, pp. 4067-4076
CHARACTERIZATION OF OLIGONUCLEOTIDE METABOLISM IN-VIVO VIA LIQUID-CHROMATOGRAPHY ELECTROSPRAY TANDEM MASS-SPECTROMETRY WITH A QUADRUPOLE ION-TRAP MASS-SPECTROMETER
Authors: GRIFFEY RH GREIG MJ GAUS HJ LIU K MONTEITH D WINNIMAN M CUMMINS LL
Citation: Rh. Griffey et al., CHARACTERIZATION OF OLIGONUCLEOTIDE METABOLISM IN-VIVO VIA LIQUID-CHROMATOGRAPHY ELECTROSPRAY TANDEM MASS-SPECTROMETRY WITH A QUADRUPOLE ION-TRAP MASS-SPECTROMETER, Journal of mass spectrometry., 32(3), 1997, pp. 305-313
PHOSPHOROTHIOATE OLIGONUCLEOTIDE METABOLISM - CHARACTERIZATION OF THEN-MER BY CE AND HPLC-ES()MS/
Authors: CUMMINS LL WINNIMAN M GAUS HJ
Citation: Ll. Cummins et al., PHOSPHOROTHIOATE OLIGONUCLEOTIDE METABOLISM - CHARACTERIZATION OF THEN-MER BY CE AND HPLC-ES()MS/, Bioorganic & medicinal chemistry letters, 7(10), 1997, pp. 1225-1230
ONLINE HPLC ELECTROSPRAY MASS-SPECTROMETRY OF PHOSPHOROTHIOATE OLIGONUCLEOTIDE METABOLITES
Authors: GAUS HJ OWENS SR WINNIMAN M COOPER S CUMMINS LL
Citation: Hj. Gaus et al., ONLINE HPLC ELECTROSPRAY MASS-SPECTROMETRY OF PHOSPHOROTHIOATE OLIGONUCLEOTIDE METABOLITES, Analytical chemistry, 69(3), 1997, pp. 313-319
SOLUTION-PHASE COMBINATORIAL CHEMISTRY - DISCOVERY OF NOVEL POLYAZAPYRIDINOPHANES WITH POTENT ANTIBACTERIAL ACTIVITY BY A SOLUTION-PHASE SIMULTANEOUS ADDITION OF FUNCTIONALITIES APPROACH
Authors: AN HY CUMMINS LL GRIFFEY RH BHARADWAJ R HALY BD FRASER AS WILSONLINGARDO L RISEN LM WYATT JR COOK PD
Citation: Hy. An et al., SOLUTION-PHASE COMBINATORIAL CHEMISTRY - DISCOVERY OF NOVEL POLYAZAPYRIDINOPHANES WITH POTENT ANTIBACTERIAL ACTIVITY BY A SOLUTION-PHASE SIMULTANEOUS ADDITION OF FUNCTIONALITIES APPROACH, Journal of the American Chemical Society, 119(16), 1997, pp. 3696-3708
ENHANCED ACTIVITY OF AN ANTISENSE OLIGONUCLEOTIDE TARGETING MURINE PROTEIN-KINASE C-ALPHA BY THE INCORPORATION OF 2'-O-PROPYL MODIFICATIONS
Authors: MCKAY RA CUMMINS LL GRAHAM MJ LESNIK EA OWENS SR WINNIMAN M DEAN NM
Citation: Ra. Mckay et al., ENHANCED ACTIVITY OF AN ANTISENSE OLIGONUCLEOTIDE TARGETING MURINE PROTEIN-KINASE C-ALPHA BY THE INCORPORATION OF 2'-O-PROPYL MODIFICATIONS, Nucleic acids research, 24(3), 1996, pp. 411-417
PHARMACOKINETIC PROPERTIES OF SEVERAL NOVEL OLIGONUCLEOTIDE ANALOGS IN MICE
Authors: CROOKE ST GRAHAM MJ ZUCKERMAN JE BROOKS D CONKLIN BS CUMMINS LL GREIG MJ GUINOSSO CJ KORNBRUST D MANOHARAN M SASMOR HM SCHLEICH T TIVEL KL GRIFFEY RH
Citation: St. Crooke et al., PHARMACOKINETIC PROPERTIES OF SEVERAL NOVEL OLIGONUCLEOTIDE ANALOGS IN MICE, The Journal of pharmacology and experimental therapeutics, 277(2), 1996, pp. 923-937
2'-O-AMINOPROPYL RIBONUCLEOTIDES - A ZWITTERIONIC MODIFICATION THAT ENHANCES THE EXONUCLEASE RESISTANCE AND BIOLOGICAL-ACTIVITY OF ANTISENSE OLIGONUCLEOTIDES
Authors: GRIFFEY RH MONIA BP CUMMINS LL FREIER S GREIG MJ GUINOSSO CJ LESNIK E MANALILI SM MOHAN V OWENS S ROSS BR SASMOR H WANCEWICZ E WEILER K WHEELER PD COOK PD
Citation: Rh. Griffey et al., 2'-O-AMINOPROPYL RIBONUCLEOTIDES - A ZWITTERIONIC MODIFICATION THAT ENHANCES THE EXONUCLEASE RESISTANCE AND BIOLOGICAL-ACTIVITY OF ANTISENSE OLIGONUCLEOTIDES, Journal of medicinal chemistry, 39(26), 1996, pp. 5100-5109
QUANTITATION OF PHOSPHOROTHIOATE OLIGONUCLEOTIDES IN HUMAN PLASMA
Authors: LEEDS JM GRAHAM MJ TRUONG L CUMMINS LL
Citation: Jm. Leeds et al., QUANTITATION OF PHOSPHOROTHIOATE OLIGONUCLEOTIDES IN HUMAN PLASMA, Analytical biochemistry, 235(1), 1996, pp. 36-43
MODIFIED OLIGONUCLEOTIDES - HYBRIDIZATION PROPERTIES, PHARMACOKINETICPROPERTIES AND PHARMACOLOGICAL ACTIVITY
Authors: FREIER SM BENNETT CF COOK PD CROOKE ST CUMMINS LL DEAN NM ECKER DJ GRIFFEY RH GUINOSSO CJ KORNBRUST D LEEDS J LESNIK EA MONIA BP SANGHVI YS ZUCKERMAN JE
Citation: Sm. Freier et al., MODIFIED OLIGONUCLEOTIDES - HYBRIDIZATION PROPERTIES, PHARMACOKINETICPROPERTIES AND PHARMACOLOGICAL ACTIVITY, Journal of cellular biochemistry, 1995, pp. 205-205
CHARACTERIZATION OF FULLY 2'-MODIFIED OLIGORIBONUCLEOTIDE HETERODUPLEX AND HOMODUPLEX HYBRIDIZATION AND NUCLEASE SENSITIVITY
Authors: CUMMINS LL OWENS SR RISEN LM LESNIK EA FREIER SM MCGEE D GUINOSSO CJ COOK PD
Citation: Ll. Cummins et al., CHARACTERIZATION OF FULLY 2'-MODIFIED OLIGORIBONUCLEOTIDE HETERODUPLEX AND HOMODUPLEX HYBRIDIZATION AND NUCLEASE SENSITIVITY, Nucleic acids research, 23(11), 1995, pp. 2019-2024
MEASUREMENT OF MACROMOLECULAR BINDING USING ELECTROSPRAY MASS-SPECTROMETRY - DETERMINATION OF DISSOCIATION-CONSTANTS FOR OLIGONUCLEOTIDE-SERUM ALBUMIN COMPLEXES
Authors: GREIG MJ GAUS H CUMMINS LL SASMOR H GRIFFEY RH
Citation: Mj. Greig et al., MEASUREMENT OF MACROMOLECULAR BINDING USING ELECTROSPRAY MASS-SPECTROMETRY - DETERMINATION OF DISSOCIATION-CONSTANTS FOR OLIGONUCLEOTIDE-SERUM ALBUMIN COMPLEXES, Journal of the American Chemical Society, 117(43), 1995, pp. 10765-10766
REMARKABLE ENHANCEMENT OF BINDING-AFFINITY OF HETEROCYCLE-MODIFIED DNA TO DNA AND RNA - SYNTHESIS, CHARACTERIZATION AND BIOPHYSICAL EVALUATION OF N-2-IMIDAZOLYLPROPYLGUANINE AND N-2-IMIDAZOLYLPROPYL-2-AMINOADENINE MODIFIED OLIGONUCLEOTIDES
Authors: RAMASAMY KS ZOUNES M GONZALEZ C FREIER SM LESNIK EA CUMMINS LL GRIFFEY RH MONIA BP COOK PD
Citation: Ks. Ramasamy et al., REMARKABLE ENHANCEMENT OF BINDING-AFFINITY OF HETEROCYCLE-MODIFIED DNA TO DNA AND RNA - SYNTHESIS, CHARACTERIZATION AND BIOPHYSICAL EVALUATION OF N-2-IMIDAZOLYLPROPYLGUANINE AND N-2-IMIDAZOLYLPROPYL-2-AMINOADENINE MODIFIED OLIGONUCLEOTIDES, Tetrahedron letters, 35(2), 1994, pp. 215-218
EFFECT OF 2'-SUBSTITUTION OF OLIGONUCLEOTIDES ON ANTISENSE INHIBITIONOF GENE-EXPRESSION
Authors: MONIA BP JOHNSTON JF CUMMINS LL OWENS SR RISEN LM LESNIK EA FREIER SM
Citation: Bp. Monia et al., EFFECT OF 2'-SUBSTITUTION OF OLIGONUCLEOTIDES ON ANTISENSE INHIBITIONOF GENE-EXPRESSION, Clinical chemistry, 40(12), 1994, pp. 2337-2337
OLIGODEOXYNUCLEOTIDES CONTAINING 2'-O-MODIFIED ADENOSINE - SYNTHESIS AND EFFECTS ON STABILITY OF DNA-RNA DUPLEXES
Authors: LESNIK EA GUINOSSO CJ KAWASAKI AM SASMOR H ZOUNES M CUMMINS LL ECKER DJ COOK PD FREIER SM
Citation: Ea. Lesnik et al., OLIGODEOXYNUCLEOTIDES CONTAINING 2'-O-MODIFIED ADENOSINE - SYNTHESIS AND EFFECTS ON STABILITY OF DNA-RNA DUPLEXES, Biochemistry, 32(30), 1993, pp. 7832-7838
Risultati: 1-16 |