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Results: 1-25 | 26-26
Results: 1-25/26
Recent advances in feeding suppressing agents: potential therapeutic strategy for the treatment of obesity
Authors: Chaki, S Nakazato, A
Citation: S. Chaki et A. Nakazato, Recent advances in feeding suppressing agents: potential therapeutic strategy for the treatment of obesity, EXPERT OP T, 11(11), 2001, pp. 1677-1692
Synthesis and structure-affinity relationships of 4-(5-aryl-1,2,3,6-tetrahydropyridino)pyrimidine derivatives as corticotropin-releasing factor(1) receptor antagonists
Authors: Kumagai, T Okubo, T Kataoka-Okubo, H Chaki, S Okuyama, S Nakazato, A
Citation: T. Kumagai et al., Synthesis and structure-affinity relationships of 4-(5-aryl-1,2,3,6-tetrahydropyridino)pyrimidine derivatives as corticotropin-releasing factor(1) receptor antagonists, BIO MED CH, 9(5), 2001, pp. 1349-1355
Chemical modification of aryl-1,2,3,6-tetrahydropyridinopyrimidine derivative to discover corticotropin-releasing factor(1) receptor antagonists: Aryl-1,2,3,6-tetrahydropyridino-purine, -3H-1,2,3-triazolo[4,5-d]pyrimidine, -purin-8-one, and -7H-pyrrolo[2,3-d]pyrimidine derivatives
Authors: Kumagai, T Okubo, T Kataoka-Okubo, H Chaki, S Okuyama, S Nakazato, A
Citation: T. Kumagai et al., Chemical modification of aryl-1,2,3,6-tetrahydropyridinopyrimidine derivative to discover corticotropin-releasing factor(1) receptor antagonists: Aryl-1,2,3,6-tetrahydropyridino-purine, -3H-1,2,3-triazolo[4,5-d]pyrimidine, -purin-8-one, and -7H-pyrrolo[2,3-d]pyrimidine derivatives, BIO MED CH, 9(5), 2001, pp. 1357-1363
Involvement of the hypothalamus-pituitary-adrenal axis in antidepressant activity of corticotropin-releasing factor subtype 1 receptor antagonists inthe rat learned helplessness test
Authors: Takamori, K Kawashima, N Chaki, S Nakazato, A Kameo, K
Citation: K. Takamori et al., Involvement of the hypothalamus-pituitary-adrenal axis in antidepressant activity of corticotropin-releasing factor subtype 1 receptor antagonists inthe rat learned helplessness test, PHARM BIO B, 69(3-4), 2001, pp. 445-449
Involvement of corticotropin-releasing factor subtype 1 receptor in the acquisition phase of learned helplessness in rats
Authors: Takamori, K Kawashima, N Chaki, S Nakazato, A Kameo, K
Citation: K. Takamori et al., Involvement of corticotropin-releasing factor subtype 1 receptor in the acquisition phase of learned helplessness in rats, LIFE SCI, 69(11), 2001, pp. 1241-1248
Neuropharmacological profiles of a novel atypical antipsychotic, NRA0562, in rats (vol 423, pg 27, 2001)
Authors: Kawashima, N Funakoshi, T Omura, T Chaki, S Kameo, K Okuyama, S
Citation: N. Kawashima et al., Neuropharmacological profiles of a novel atypical antipsychotic, NRA0562, in rats (vol 423, pg 27, 2001), EUR J PHARM, 428(3), 2001, pp. 389-390
Neuropharmacological profiles of a novel atypical antipsychotic, NRA0562, in rats
Authors: Kawashima, N Funakoshi, T Omura, T Chaki, S Kameo, K Okuyama, S
Citation: N. Kawashima et al., Neuropharmacological profiles of a novel atypical antipsychotic, NRA0562, in rats, EUR J PHARM, 423(1), 2001, pp. 27-33
Localization and characterization of a short isoform of the corticotropin-releasing factor receptor type 2 alpha (CRF2 alpha-tr) in the rat brain
Authors: Miyata, I Shiota, C Chaki, S Okuyama, S Inagami, T
Citation: I. Miyata et al., Localization and characterization of a short isoform of the corticotropin-releasing factor receptor type 2 alpha (CRF2 alpha-tr) in the rat brain, BIOC BIOP R, 280(2), 2001, pp. 553-557
Design, synthesis and structure-affinity relationships of 4-methylidenepiperidine and 4-aryl-1,2,3,6-tetrahydropyridine derivatives as corticotropin-releasing factor(1) receptor antagonists
Authors: Nakazato, A Kumagai, T Okubo, T Tanaka, H Chaki, S Okuyama, S Tomisawa, K
Citation: A. Nakazato et al., Design, synthesis and structure-affinity relationships of 4-methylidenepiperidine and 4-aryl-1,2,3,6-tetrahydropyridine derivatives as corticotropin-releasing factor(1) receptor antagonists, BIO MED CH, 8(5), 2000, pp. 1183-1193
Synthesis, SARs, and pharmacological characterization of 2-amino-3 or 6-fluorobicyclo[3.1.0]hexane-2,6-dicarboxylic acid derivatives as potent, selective, and orally active group II metabotropic glutamate receptor agonists
Authors: Nakazato, A Kumagai, T Sakagami, K Yoshikawa, R Suzuki, Y Chaki, S Ito, H Taguchi, T Nakanishi, S Okuyama, S
Citation: A. Nakazato et al., Synthesis, SARs, and pharmacological characterization of 2-amino-3 or 6-fluorobicyclo[3.1.0]hexane-2,6-dicarboxylic acid derivatives as potent, selective, and orally active group II metabotropic glutamate receptor agonists, J MED CHEM, 43(25), 2000, pp. 4893-4909
In vivo receptor labeling of peripheral benzodiazepine receptor by ex vivobinding of [H-3]PK11195
Authors: Funakoshi, T Chaki, S Okuyama, S Okubo, T Nakazato, A Nagamine, M Tomisawa, K
Citation: T. Funakoshi et al., In vivo receptor labeling of peripheral benzodiazepine receptor by ex vivobinding of [H-3]PK11195, RES COM M P, 105(1-2), 1999, pp. 35-41
Chemical modification of apomorphine to discover sigma ligands: 6H-dibenzo[b,d]pyran and carbazole analogues
Authors: Nakazato, A Sekiguchi, Y Ohta, K Chaki, S Okuyama, S
Citation: A. Nakazato et al., Chemical modification of apomorphine to discover sigma ligands: 6H-dibenzo[b,d]pyran and carbazole analogues, BIO MED CH, 7(9), 1999, pp. 2027-2035
A novel layout optimization technique for miniaturization and accurate design of MMICs
Authors: Chaki, S Sasaki, Y Andoh, N Nakajima, Y Nishitani, K
Citation: S. Chaki et al., A novel layout optimization technique for miniaturization and accurate design of MMICs, IEICE TR EL, E82C(11), 1999, pp. 1960-1967
A global multimedia research collaberation between the University of Chileand NTT Laboratories
Authors: Inoue, Y Vera, ES Yamamoto, H Hagishima, K Ishii, S Chaki, S Tsuji, Y Morikawa, K Yokoi, H Wakabayashi, K Yamauchi, N
Citation: Y. Inoue et al., A global multimedia research collaberation between the University of Chileand NTT Laboratories, NTT REVIEW, 11(2), 1999, pp. 34-37
Effects of NRA0045, NRA0160, and NRA0215 on regional Fos-like immunoreactivity in the rat brain
Authors: Kawashima, N Nakamura, A Okuyama, S Chaki, S Tomisawa, K
Citation: N. Kawashima et al., Effects of NRA0045, NRA0160, and NRA0215 on regional Fos-like immunoreactivity in the rat brain, GEN PHARM, 32(6), 1999, pp. 637-646
In vivo receptor occupancy of NRA0045, a putative atypical antipsychotic, in rats
Authors: Chaki, S Funakoshi, T Yoshikawa, R Okuyama, S Kumagai, T Nakazato, A Nagamine, M Tomisawa, K
Citation: S. Chaki et al., In vivo receptor occupancy of NRA0045, a putative atypical antipsychotic, in rats, NEUROPHARM, 38(8), 1999, pp. 1185-1194
Effects of selective dopamine D-4 receptor blockers, NRA0160 and L-745,870, on A9 and A10 dopamine neurons in rats
Authors: Kawashima, N Okuyama, S Omura, T Chaki, S Tomisawa, K
Citation: N. Kawashima et al., Effects of selective dopamine D-4 receptor blockers, NRA0160 and L-745,870, on A9 and A10 dopamine neurons in rats, LIFE SCI, 65(24), 1999, pp. 2561-2571
A selective dopamine D-4 receptor antagonist, NRA0160: A preclinical neuropharmacological profile
Authors: Okuyama, S Kawashima, N Chaki, S Yoshikawa, R Funakoshi, T Ogawa, S Suzuki, Y Ikeda, Y Kumagai, T Nakazato, A Nagamine, M Tomisawa, K
Citation: S. Okuyama et al., A selective dopamine D-4 receptor antagonist, NRA0160: A preclinical neuropharmacological profile, LIFE SCI, 65(20), 1999, pp. 2109-2125
Neuropharmacological profile of peripheral benzodiazepine receptor agonists, DAA1097 and DAA1106
Authors: Okuyama, S Chaki, S Yoshikawa, R Ogawa, S Suzuki, Y Okubo, T Nakazato, A Nagamine, M Tomisawa, K
Citation: S. Okuyama et al., Neuropharmacological profile of peripheral benzodiazepine receptor agonists, DAA1097 and DAA1106, LIFE SCI, 64(16), 1999, pp. 1455-1464
Receptor binding, behavioral, and electrophysiological profiles of nonpeptide corticotropin-releasing factor subtype 1 receptor antagonists CRA1000 and CRA1001
Authors: Okuyama, S Chaki, S Kawashima, N Suzuki, Y Ogawa, SI Nakazato, A Kumagai, T Okubo, T Tomisawa, K
Citation: S. Okuyama et al., Receptor binding, behavioral, and electrophysiological profiles of nonpeptide corticotropin-releasing factor subtype 1 receptor antagonists CRA1000 and CRA1001, J PHARM EXP, 289(2), 1999, pp. 926-935
Design, synthesis, structure-activity relationships, and biological characterization of novel arylalkoxyphenylalkylamine sigma ligands as potential antipsychotic drugs
Authors: Nakazato, A Ohta, K Sekiguchi, Y Okuyama, S Chaki, S Kawashima, Y Hatayama, K
Citation: A. Nakazato et al., Design, synthesis, structure-activity relationships, and biological characterization of novel arylalkoxyphenylalkylamine sigma ligands as potential antipsychotic drugs, J MED CHEM, 42(6), 1999, pp. 1076-1087
Synthesis and SAR of 1-alkyl-2-phenylethylamine derivatives designed from N,N-dipropyl-4-methoxy-3-(2-phenylethoxy)phenylethylamine to discover sigma(1) ligands
Authors: Nakazato, A Kumagai, T Ohta, K Chaki, S Okuyama, S Tomisawa, K
Citation: A. Nakazato et al., Synthesis and SAR of 1-alkyl-2-phenylethylamine derivatives designed from N,N-dipropyl-4-methoxy-3-(2-phenylethoxy)phenylethylamine to discover sigma(1) ligands, J MED CHEM, 42(19), 1999, pp. 3965-3970
Binding characteristics of [H-3]DAA1106, a novel and selective ligand for peripheral benzodiazepine receptors
Authors: Chaki, S Funakoshi, T Yoshikawa, R Okuyama, S Okubo, T Nakazato, A Nagamine, M Tomisawa, K
Citation: S. Chaki et al., Binding characteristics of [H-3]DAA1106, a novel and selective ligand for peripheral benzodiazepine receptors, EUR J PHARM, 371(2-3), 1999, pp. 197-204
In vitro pharmacological profile of nonpeptide CRF1 receptor antagonists, CRA1000 and CRA1001
Authors: Chaki, S Okuyama, S Nakazato, A Kumagai, T Okubo, T Ikeda, Y Oshida, Y Hamajima, Y Tomisawa, K
Citation: S. Chaki et al., In vitro pharmacological profile of nonpeptide CRF1 receptor antagonists, CRA1000 and CRA1001, EUR J PHARM, 371(2-3), 1999, pp. 205-211
Anxiety-like behavior in mice lacking the angiotensin II type-2 receptor
Authors: Okuyama, S Sakagawa, T Chaki, S Imagawa, Y Ichiki, T Inagami, T
Citation: S. Okuyama et al., Anxiety-like behavior in mice lacking the angiotensin II type-2 receptor, BRAIN RES, 821(1), 1999, pp. 150-159
Risultati: 1-25 | 26-26