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Results: 1-7 |
Results: 7
Parallel extraction columns and parallel analytical columns coupled with liquid chromatography/tandem mass spectrometry for on-line simultaneous quantification of a drug candidate and its six metabolites in dog plasma
Authors: Xia, YQ Hop, CECA Liu, DQ Vincent, SH Chiu, SHL
Citation: Yq. Xia et al., Parallel extraction columns and parallel analytical columns coupled with liquid chromatography/tandem mass spectrometry for on-line simultaneous quantification of a drug candidate and its six metabolites in dog plasma, RAP C MASS, 15(22), 2001, pp. 2135-2144
Use of on-line hydrogen/deuterium exchange to facilitate metabolite identification
Authors: Liu, DQ Hop, CECA Beconi, MG Mao, A Chiu, SHL
Citation: Dq. Liu et al., Use of on-line hydrogen/deuterium exchange to facilitate metabolite identification, RAP C MASS, 15(19), 2001, pp. 1832-1839
Phosphorylated morpholine acetal human neurokinin-1 receptor antagonists as water-soluble prodrugs
Authors: Hale, JJ Mills, SG MacCoss, M Dorn, CP Finke, PE Budhu, RJ Reamer, RA Huskey, SEW Luffer-Atlas, D Dean, BJ McGowan, EM Feeney, WP Chiu, SHL Cascieri, MA Chicchi, GG Kurtz, MM Sadowski, S Ber, E Tattersall, FD Rupniak, NMJ Williams, AR Rycroft, W Hargreaves, R Metzger, JM MacIntyre, DE
Citation: Jj. Hale et al., Phosphorylated morpholine acetal human neurokinin-1 receptor antagonists as water-soluble prodrugs, J MED CHEM, 43(6), 2000, pp. 1234-1241
L-770,644: A potent and selective human beta(3) adrenergic receptor agonist with improved oral bioavailability
Authors: Shih, TL Candelore, MR Cascieri, MA Chiu, SHL Colwell, LF Deng, LP Feeney, WP Forrest, MJ Hom, GJ MacIntyre, DE Miller, RR Stearns, RA Strader, CD Tota, L Wyvratt, MJ Fisher, MH Weber, AE
Citation: Tl. Shih et al., L-770,644: A potent and selective human beta(3) adrenergic receptor agonist with improved oral bioavailability, BIOORG MED, 9(9), 1999, pp. 1251-1254
Roles of human hepatic cytochrome P450s 2C9 and 3A4 in the metabolic activation of diclofenac
Authors: Tang, W Stearns, RA Wang, RW Chiu, SHL Baillie, TA
Citation: W. Tang et al., Roles of human hepatic cytochrome P450s 2C9 and 3A4 in the metabolic activation of diclofenac, CHEM RES T, 12(2), 1999, pp. 192-199
Studies on cytochrome P-450-mediated bioactivation of diclofenac in rats and in human hepatocytes: Identification of glutathione conjugated metabolites
Authors: Tang, W Stearns, RA Bandiera, SM Zhang, Y Raab, C Braun, MP Dean, DC Pang, JM Leung, KH Doss, GA Strauss, JR Kwei, GY Rushmore, TH Chiu, SHL Baillie, TA
Citation: W. Tang et al., Studies on cytochrome P-450-mediated bioactivation of diclofenac in rats and in human hepatocytes: Identification of glutathione conjugated metabolites, DRUG META D, 27(3), 1999, pp. 365-372
Substance P receptor antagonist I: Conversion of phosphoramidate prodrug after i.v. administration to rats and dogs
Authors: Huskey, SEW Luffer-Atlas, D Dean, BJ McGowan, EM Feeney, WP Chiu, SHL
Citation: Sew. Huskey et al., Substance P receptor antagonist I: Conversion of phosphoramidate prodrug after i.v. administration to rats and dogs, DRUG META D, 27(11), 1999, pp. 1367-1373
Risultati: 1-7 |