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Results: 1-25 | 26-36
Results: 1-25/36
Comparison of the effects of tacrolimus and cyclosporine on the pharmacokinetics of mycophenolic acid
Authors: van Gelder, T Klupp, J Barten, MJ Christians, U Morris, RE
Citation: T. Van Gelder et al., Comparison of the effects of tacrolimus and cyclosporine on the pharmacokinetics of mycophenolic acid, THER DRUG M, 23(2), 2001, pp. 119-128
ATP-binding cassette transporters and calcineurin inhibitors: Potential clinical implications
Authors: van Gelder, T Klupp, J Sawamoto, T Christians, U Morris, RE
Citation: T. Van Gelder et al., ATP-binding cassette transporters and calcineurin inhibitors: Potential clinical implications, TRANSPLAN P, 33(3), 2001, pp. 2420-2421
Comparison of the in vitro metabolism of the macrolide immunosuppressants sirolimus and RAD
Authors: Jacobsen, W Serkova, N Hausen, B Morris, RE Benet, LZ Christians, U
Citation: W. Jacobsen et al., Comparison of the in vitro metabolism of the macrolide immunosuppressants sirolimus and RAD, TRANSPLAN P, 33(1-2), 2001, pp. 514-515
Fast quantification method for sirolimus and its major metabolites
Authors: Kirchner, GI Jacobsen, W Deters, M Christians, U Nashan, B Winkler, M Vidal, C Kaever, V Sewing, KF Manns, MP
Citation: Gi. Kirchner et al., Fast quantification method for sirolimus and its major metabolites, TRANSPLAN P, 33(1-2), 2001, pp. 1091-1092
Coadministration of either cyclosporine or steroids with humanized monoclonal antibodies against CD80 and CD86 successfully prolong allograft survival after life supporting renal transplantation in cynomolgus monkeys
Authors: Hausen, B Klupp, J Christians, U Higgins, JP Baumgartner, RE Hook, LE Friedrich, S Celnicker, A Morris, RE
Citation: B. Hausen et al., Coadministration of either cyclosporine or steroids with humanized monoclonal antibodies against CD80 and CD86 successfully prolong allograft survival after life supporting renal transplantation in cynomolgus monkeys, TRANSPLANT, 72(6), 2001, pp. 1128-1137
Metabolism of sirolimus and its derivative everolimus by cytochrome P450 3A4: Insights from docking, molecular dynamics, and quantum chemical calculations
Authors: Kuhn, B Jacobsen, W Christians, U Benet, LZ Kollman, PA
Citation: B. Kuhn et al., Metabolism of sirolimus and its derivative everolimus by cytochrome P450 3A4: Insights from docking, molecular dynamics, and quantum chemical calculations, J MED CHEM, 44(12), 2001, pp. 2027-2034
Red wine decreases cyclosporine bioavailability
Authors: Tsunoda, SM Harris, RZ Christians, U Velez, RL Freeman, RB Benet, LZ Warshaw, A
Citation: Sm. Tsunoda et al., Red wine decreases cyclosporine bioavailability, CLIN PHARM, 70(5), 2001, pp. 462-467
The pharmacokinetics and metabolic disposition of tacrolimus: A comparisonacross ethnic groups
Authors: Mancinelli, LM Frassetto, L Floren, LC Dressler, D Carrier, S Bekersky, I Benet, LZ Christians, U
Citation: Lm. Mancinelli et al., The pharmacokinetics and metabolic disposition of tacrolimus: A comparisonacross ethnic groups, CLIN PHARM, 69(1), 2001, pp. 24-31
Sirolimus, but not the structurally related RAD (everolimus), enhances thenegative effects of cyclosporine on mitochondrial metabolism in the rat brain
Authors: Serkova, N Jacobsen, W Niemann, CU Litt, L Benet, LZ Leibfritz, D Christians, U
Citation: N. Serkova et al., Sirolimus, but not the structurally related RAD (everolimus), enhances thenegative effects of cyclosporine on mitochondrial metabolism in the rat brain, BR J PHARM, 133(6), 2001, pp. 875-885
Overcoming MDR by ultrasound-induced hyperthermia and P-glycoprotein modulation
Authors: Liu, Y Lillehei, K Cobb, WN Christians, U Ng, KY
Citation: Y. Liu et al., Overcoming MDR by ultrasound-induced hyperthermia and P-glycoprotein modulation, BIOC BIOP R, 289(1), 2001, pp. 62-68
Automated, fast and sensitive quantification of drugs in blood by liquid chromatography-mass spectrometry with on-line extraction: immunosuppressants
Authors: Christians, U Jacobsen, W Serkova, N Benet, LZ Vidal, C Sewing, KF Manns, MP Kirchner, GI
Citation: U. Christians et al., Automated, fast and sensitive quantification of drugs in blood by liquid chromatography-mass spectrometry with on-line extraction: immunosuppressants, J CHROMAT B, 748(1), 2000, pp. 41-53
Recommendations for bioequivalence testing of cyclosporine generics revisited
Authors: Christians, U First, MR Benet, LZ
Citation: U. Christians et al., Recommendations for bioequivalence testing of cyclosporine generics revisited, THER DRUG M, 22(3), 2000, pp. 330-345
In vitro evaluation of the disposition of a novel cysteine protease inhibitor
Authors: Jacobsen, W Christians, U Benet, LZ
Citation: W. Jacobsen et al., In vitro evaluation of the disposition of a novel cysteine protease inhibitor, DRUG META D, 28(11), 2000, pp. 1343-1351
Lactonization is the critical first step in the disposition of the 3-hydroxy-3-methylglutaryl-CoA reductase inhibitor atorvastatin
Authors: Jacobsen, W Kuhn, B Soldner, A Kirchner, G Sewing, KF Kollman, PA Benet, LZ Christians, U
Citation: W. Jacobsen et al., Lactonization is the critical first step in the disposition of the 3-hydroxy-3-methylglutaryl-CoA reductase inhibitor atorvastatin, DRUG META D, 28(11), 2000, pp. 1369-1378
An ex vivo model to study the intestinal biotransformation of immunosuppressive drugs
Authors: Braun, F Christians, U Laabs, S Elias, K Shipkova, M Schutz, E Ringe, B
Citation: F. Braun et al., An ex vivo model to study the intestinal biotransformation of immunosuppressive drugs, TRANSPLAN P, 32(7), 2000, pp. 1999-1999
An ex vivo model to study the intestinal biotransformation of immunosuppressives
Authors: Braun, F Christians, U Laabs, S Elias, K Shipkova, M Schutz, E Ringe, B
Citation: F. Braun et al., An ex vivo model to study the intestinal biotransformation of immunosuppressives, TRANSPLAN P, 32(7), 2000, pp. 2536-2536
Sirolimus (rapamycin) halts and reverses progression of allograft vasculardisease in non-human primates
Authors: Ikonen, TS Gummert, JF Hayase, M Honda, Y Hausen, B Christians, U Berry, GJ Yock, PG Morris, RE
Citation: Ts. Ikonen et al., Sirolimus (rapamycin) halts and reverses progression of allograft vasculardisease in non-human primates, TRANSPLANT, 70(6), 2000, pp. 969-975
Prevention of acute allograft rejection in nonhuman primate lung transplant recipients - Induction with chimeric anti-interleukin-2 receptor monoclonal antibody improves the tolerability and potentiates the immunosuppressiveactivity of a regimen using low doses of both microemulsion cyclosporine and 40-O-(2-hydroxyethyl)-rapamycin
Authors: Hausen, B Gummert, J Berry, GJ Christians, U Serkova, N Ikonen, T Hook, L Legay, F Schuler, W Schreier, MH Morris, RE
Citation: B. Hausen et al., Prevention of acute allograft rejection in nonhuman primate lung transplant recipients - Induction with chimeric anti-interleukin-2 receptor monoclonal antibody improves the tolerability and potentiates the immunosuppressiveactivity of a regimen using low doses of both microemulsion cyclosporine and 40-O-(2-hydroxyethyl)-rapamycin, TRANSPLANT, 69(4), 2000, pp. 488-496
Combined immunosuppression with cyclosporine (Neoral) and SDZ RAD in non-human primate lung transplantation: Systematic pharmacokinetic-based trials to improve efficacy and tolerability
Authors: Hausen, B Ikonen, T Briffa, N Berry, GJ Christians, U Robbins, RC Hook, L Serkova, N Benet, LZ Schuler, W Morris, RE
Citation: B. Hausen et al., Combined immunosuppression with cyclosporine (Neoral) and SDZ RAD in non-human primate lung transplantation: Systematic pharmacokinetic-based trials to improve efficacy and tolerability, TRANSPLANT, 69(1), 2000, pp. 76-86
Tissue distribution and clinical monitoring of the novel macrolide immunosuppressant SDZ-RAD and its metabolites in monkey lung transplant recipients: Interaction with cyclosporine
Authors: Serkova, N Hausen, B Berry, GJ Jacobsen, W Benet, LZ Morris, RE Christians, U
Citation: N. Serkova et al., Tissue distribution and clinical monitoring of the novel macrolide immunosuppressant SDZ-RAD and its metabolites in monkey lung transplant recipients: Interaction with cyclosporine, J PHARM EXP, 294(1), 2000, pp. 323-332
Active transport of the angiotensin-II antagonist losartan and its main metabolite EXP 3174 across MDCK-MDR1 and Caco-2 cell monolayers
Authors: Soldner, A Benet, LZ Mutschler, E Christians, U
Citation: A. Soldner et al., Active transport of the angiotensin-II antagonist losartan and its main metabolite EXP 3174 across MDCK-MDR1 and Caco-2 cell monolayers, BR J PHARM, 129(6), 2000, pp. 1235-1243
The novel immunosuppressant SDZ-RAD protects rat brain slices from cyclosporine-induced reduction of high-energy phosphates
Authors: Serkova, N Litt, L Leibfritz, D Hausen, B Morris, RE James, TL Benet, LZ Christians, U
Citation: N. Serkova et al., The novel immunosuppressant SDZ-RAD protects rat brain slices from cyclosporine-induced reduction of high-energy phosphates, BR J PHARM, 129(3), 2000, pp. 485-492
Successful treatment of acute, ongoing rat lung allograft rejection with the novel immunosuppressant SDZ-RAD
Authors: Hausen, B Boeke, K Berry, GJ Christians, U Schuler, W Morris, RE
Citation: B. Hausen et al., Successful treatment of acute, ongoing rat lung allograft rejection with the novel immunosuppressant SDZ-RAD, ANN THORAC, 69(3), 2000, pp. 904-909
Simultaneous on-line extraction and analysis of sirolimus (rapamycin) and ciclosporin in blood by liquid chromatography electrospray mass spectrometry
Authors: Kirchner, GI Vidal, C Jacobsen, W Franzke, A Hallensleben, K Christians, U Sewing, KF
Citation: Gi. Kirchner et al., Simultaneous on-line extraction and analysis of sirolimus (rapamycin) and ciclosporin in blood by liquid chromatography electrospray mass spectrometry, J CHROMAT B, 721(2), 1999, pp. 285-294
High-performance liquid chromatographic assay with a simple extraction procedure for sensitive quantification of mycophenolic acid in rat and human plasma
Authors: Gummert, JF Christians, U Barten, M Silva, H Morris, RE
Citation: Jf. Gummert et al., High-performance liquid chromatographic assay with a simple extraction procedure for sensitive quantification of mycophenolic acid in rat and human plasma, J CHROMAT B, 721(2), 1999, pp. 321-326
Risultati: 1-25 | 26-36