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Results: 1-18 |
Results: 18
SYNTHESIS OF TETRAZOLE ANALOGS OF ALPHA-AMINO-ACIDS BY ALKYLATION OF A SCHIFF-BASE OF ALPHA-AMINOMETHYLTETRAZOLE
Authors: SATOH Y DELOMBAERT S MARCOPULOS N MOLITERNI J MOSKAL M TAN J WALLACE E
Citation: Y. Satoh et al., SYNTHESIS OF TETRAZOLE ANALOGS OF ALPHA-AMINO-ACIDS BY ALKYLATION OF A SCHIFF-BASE OF ALPHA-AMINOMETHYLTETRAZOLE, Tetrahedron letters, 39(21), 1998, pp. 3367-3370
ANTIHYPERTENSIVE AND NATRIURETIC EFFECTS OF CGS-30440, A DUAL INHIBITOR OF ANGIOTENSIN-CONVERTING ENZYME AND NEUTRAL ENDOPEPTIDASE-24.11
Authors: CHATELAIN RE GHAI RD TRAPANI AJ ODORICO LM DARDIK BN DELOMBAERT S LAPPE RW FINK CA
Citation: Re. Chatelain et al., ANTIHYPERTENSIVE AND NATRIURETIC EFFECTS OF CGS-30440, A DUAL INHIBITOR OF ANGIOTENSIN-CONVERTING ENZYME AND NEUTRAL ENDOPEPTIDASE-24.11, The Journal of pharmacology and experimental therapeutics, 284(3), 1998, pp. 974-982
POTENT NONPEPTIDIC DUAL INHIBITORS OF ENDOTHELIN-CONVERTING ENZYME AND NEUTRAL ENDOPEPTIDASE-24.11
Authors: DELOMBAERT S STAMFORD LB BLANCHARD L TAN J HOYER D DIEFENBACHER CG WEI DC WALLACE EM MOSKAL MA SAVAGE P JENG AY
Citation: S. Delombaert et al., POTENT NONPEPTIDIC DUAL INHIBITORS OF ENDOTHELIN-CONVERTING ENZYME AND NEUTRAL ENDOPEPTIDASE-24.11, Bioorganic & medicinal chemistry letters, 7(8), 1997, pp. 1059-1064
DUAL INHIBITION OF ANGIOTENSIN-CONVERTING ENZYME AND NEUTRAL ENDOPEPTIDASE BY TRICYCLIC BENZAZEPINONE THIOLS
Authors: DELOMBAERT S BLANCHARD L STAMFORD LB SAKANE Y BERRY C GHAI RD TRAPANI AJ
Citation: S. Delombaert et al., DUAL INHIBITION OF ANGIOTENSIN-CONVERTING ENZYME AND NEUTRAL ENDOPEPTIDASE BY TRICYCLIC BENZAZEPINONE THIOLS, Bioorganic & medicinal chemistry letters, 6(23), 1996, pp. 2875-2880
3-DIMENSIONAL MODELS OF ACE AND NEP INHIBITORS AND THEIR USE IN THE DESIGN OF POTENT DUAL ACE NEP INHIBITORS/
Authors: BOHACEK R DELOMBAERT S MCMARTIN C PRIESTLE J GRUTTER M
Citation: R. Bohacek et al., 3-DIMENSIONAL MODELS OF ACE AND NEP INHIBITORS AND THEIR USE IN THE DESIGN OF POTENT DUAL ACE NEP INHIBITORS/, Journal of the American Chemical Society, 118(35), 1996, pp. 8231-8249
A RAPID INDIRECT METHOD TO DETERMINE THE PLASMA-CONCENTRATIONS OF NEUTRAL ENDOPEPTIDASE INHIBITORS
Authors: GHAI RD DELOMBAERT S KSANDER GM BERRY C SAKANE Y TRAPANI AJ
Citation: Rd. Ghai et al., A RAPID INDIRECT METHOD TO DETERMINE THE PLASMA-CONCENTRATIONS OF NEUTRAL ENDOPEPTIDASE INHIBITORS, Research communications in molecular pathology and pharmacology, 87(2), 1995, pp. 211-220
NONPEPTIDIC INHIBITORS OF NEUTRAL ENDOPEPTIDASE-24.11 .1. DISCOVERY AND OPTIMIZATION OF POTENCY
Authors: DELOMBAERT S BLANCHARD L TAN J SAKANE Y BERRY C GHAI RD
Citation: S. Delombaert et al., NONPEPTIDIC INHIBITORS OF NEUTRAL ENDOPEPTIDASE-24.11 .1. DISCOVERY AND OPTIMIZATION OF POTENCY, Bioorganic & medicinal chemistry letters, 5(2), 1995, pp. 145-150
NONPEPTIDIC INHIBITORS OP NEUTRAL ENDOPEPTIDASE-24.11 .2. DESIGN AND PHARMACOLOGY OF ORALLY-ACTIVE PHOSPHONATE PRODRUGS
Authors: DELOMBAERT S BLANCHARD L BERRY C GHAI RD TRAPANI AJ
Citation: S. Delombaert et al., NONPEPTIDIC INHIBITORS OP NEUTRAL ENDOPEPTIDASE-24.11 .2. DESIGN AND PHARMACOLOGY OF ORALLY-ACTIVE PHOSPHONATE PRODRUGS, Bioorganic & medicinal chemistry letters, 5(2), 1995, pp. 151-154
INHIBITION OF BIG ET-1-INDUCED PRESSOR-RESPONSE BY AN ORALLY-ACTIVE DUAL INHIBITOR OF ENDOTHELIN-CONVERTING ENZYME AND NEUTRAL ENDOPEPTIDASE-24.11
Authors: TRAPANI AJ DELOMBAERT S KUZMICH S JENG AY
Citation: Aj. Trapani et al., INHIBITION OF BIG ET-1-INDUCED PRESSOR-RESPONSE BY AN ORALLY-ACTIVE DUAL INHIBITOR OF ENDOTHELIN-CONVERTING ENZYME AND NEUTRAL ENDOPEPTIDASE-24.11, Journal of cardiovascular pharmacology, 26, 1995, pp. 69-71
CHEMICAL AND PLASMA HYDROLYZES OF A DIPHENYL ALPHA-AMINOMETHYL PHOSPHONATE PRODRUG INHIBITOR OF NEUTRAL ENDOPEPTIDASE-24.11
Authors: DELOMBAERT S SINGH K BLANCHARD L SOLIMAN VF
Citation: S. Delombaert et al., CHEMICAL AND PLASMA HYDROLYZES OF A DIPHENYL ALPHA-AMINOMETHYL PHOSPHONATE PRODRUG INHIBITOR OF NEUTRAL ENDOPEPTIDASE-24.11, Bioorganic & medicinal chemistry letters, 4(7), 1994, pp. 899-902
DUAL INHIBITION OF NEUTRAL ENDOPEPTIDASE AND ANGIOTENSIN-CONVERTING ENZYME BY N-PHOSPHONOMETHYL AND N-CARBOXYALKYL DIPEPTIDES
Authors: DELOMBAERT S TAN J STAMFORD LJ SAKANE Y BERRY C GHAI RD
Citation: S. Delombaert et al., DUAL INHIBITION OF NEUTRAL ENDOPEPTIDASE AND ANGIOTENSIN-CONVERTING ENZYME BY N-PHOSPHONOMETHYL AND N-CARBOXYALKYL DIPEPTIDES, Bioorganic & medicinal chemistry letters, 4(22), 1994, pp. 2715-2720
A RAPID INDIRECT METHOD TO DETERMINE THE PHARMACOKINETICS OF NEUTRAL ENDOPEPTIDASE (NEP-3.4.24.11) INHIBITORS
Authors: GHAI RD DELOMBAERT S KSANDER GM BERRY C SAKANE Y TRAPANI AJ
Citation: Rd. Ghai et al., A RAPID INDIRECT METHOD TO DETERMINE THE PHARMACOKINETICS OF NEUTRAL ENDOPEPTIDASE (NEP-3.4.24.11) INHIBITORS, The FASEB journal, 8(4), 1994, pp. 10000099-10000099
INHIBITION OF NEUTRAL ENDOPEPTIDASE-24.11 (NEP) AND ENDOTHELIN-CONVERTING ENZYME (ECE) BY AMINOPHOSPHONATE ANALOGS IN-VITRO AND IN-VIVO
Authors: TRAPANI AJ BEIL ME BERRY C DELOMBAERT S GERLOCK TE GHAI RD GRAYBILL SC JENG AY SAKANE Y SAVAGE P
Citation: Aj. Trapani et al., INHIBITION OF NEUTRAL ENDOPEPTIDASE-24.11 (NEP) AND ENDOTHELIN-CONVERTING ENZYME (ECE) BY AMINOPHOSPHONATE ANALOGS IN-VITRO AND IN-VIVO, The FASEB journal, 8(4), 1994, pp. 10000104-10000104
PHARMACOLOGICAL PROFILE OF CGS-24128, A POTENT, LONG-ACTING INHIBITOROF NEUTRAL ENDOPEPTIDASE-24.11
Authors: TRAPANI AJ BELL ME COTE DT DELOMBAERT S ERION MD GERLOCK TE GHAI RD HOPKINS MF PEPPARD JV WEBB RL LAPPE RW WORCEL M
Citation: Aj. Trapani et al., PHARMACOLOGICAL PROFILE OF CGS-24128, A POTENT, LONG-ACTING INHIBITOROF NEUTRAL ENDOPEPTIDASE-24.11, Journal of cardiovascular pharmacology, 23(3), 1994, pp. 358-364
PRACTICAL SYNTHESES OF A NOVEL TRICYCLIC DIPEPTIDE MIMETIC BASED ON A[6H]-AZEPINO INDOLINE NUCLEUS - APPLICATION TO ANGIOTENSIN-CONVERTINGENZYME-INHIBITION
Authors: DELOMBAERT S BLANCHARD L STAMFORD LB SPERBECK DM GRIM MD JENSON TM RODRIGUEZ HR
Citation: S. Delombaert et al., PRACTICAL SYNTHESES OF A NOVEL TRICYCLIC DIPEPTIDE MIMETIC BASED ON A[6H]-AZEPINO INDOLINE NUCLEUS - APPLICATION TO ANGIOTENSIN-CONVERTINGENZYME-INHIBITION, Tetrahedron letters, 35(41), 1994, pp. 7513-7516
N-PHOSPHONOMETHYL DIPEPTIDES AND THEIR PHOSPHONATE PRODRUGS, A NEW-GENERATION OF NEUTRAL ENDOPEPTIDASE (NEP,EC-3.4.24.11) INHIBITORS
Authors: DELOMBAERT S ERION MD TAN J BLANCHARD L ELCHEHABI L GHAI RD SAKANE Y BERRY C TRAPANI AJ
Citation: S. Delombaert et al., N-PHOSPHONOMETHYL DIPEPTIDES AND THEIR PHOSPHONATE PRODRUGS, A NEW-GENERATION OF NEUTRAL ENDOPEPTIDASE (NEP,EC-3.4.24.11) INHIBITORS, Journal of medicinal chemistry, 37(4), 1994, pp. 498-511
PHARMACOLOGICAL PROFILE OF A NONPEPTIDIC DUAL INHIBITOR OF NEUTRAL ENDOPEPTIDASE-24.11 AND ENDOTHELIN-CONVERTING ENZYME
Authors: DELOMBAERT S GHAI RD JENG AY TRAPANI AJ WEBB RL
Citation: S. Delombaert et al., PHARMACOLOGICAL PROFILE OF A NONPEPTIDIC DUAL INHIBITOR OF NEUTRAL ENDOPEPTIDASE-24.11 AND ENDOTHELIN-CONVERTING ENZYME, Biochemical and biophysical research communications, 204(1), 1994, pp. 407-412
THE PHARMACOLOGY OF CCS-25462 - A POTENT, ORALLY BIOAVAILABLE, LONG-ACTING INHIBITOR OF NEUTRAL ENDOPEPTIDASE 24.11
Authors: TRAPANI AJ DELOMBAERT S ERION MD GHAI RD PEPPARD JV LAPPE RW WORCEL M
Citation: Aj. Trapani et al., THE PHARMACOLOGY OF CCS-25462 - A POTENT, ORALLY BIOAVAILABLE, LONG-ACTING INHIBITOR OF NEUTRAL ENDOPEPTIDASE 24.11, Journal of hypertension, 11, 1993, pp. 190000220-190000221
Risultati: 1-18 |