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Results: 1-7 |
Results: 7
Bone-targeted Src SH2 inhibitors block Src cellular activity and osteoclast-mediated resorption
Authors: Violette, SM Guan, W Bartlett, C Smith, JA Bardelay, C Antoine, E Rickles, RJ Mandine, E Van Schravendijk, MR Adams, SE Lynch, BA Shakespeare, WC Yang, M Jacobsen, VA Takeuchi, CS Macek, KJ Bohacek, RS Dalgarno, DC Weigele, M Lesuisse, D Sawyer, TK Baron, R
Citation: Sm. Violette et al., Bone-targeted Src SH2 inhibitors block Src cellular activity and osteoclast-mediated resorption, BONE, 28(1), 2001, pp. 54-64
A novel phosphotyrosine mimetic 4 '-carboxymethyloxy-3 '-phosphonophenylalanine (Cpp): Exploitation in the design of nonpeptide inhibitors of pp60(Src) SH2 domain
Authors: Kawahata, N Yang, MG Luke, GP Shakespeare, WC Sundaramoorthi, R Wang, YH Johnson, D Merry, T Violette, S Guan, W Bartlett, C Smith, J Hatada, M Lu, XD Dalgarno, DC Eyermann, CJ Bohacek, RS Sawyer, TK
Citation: N. Kawahata et al., A novel phosphotyrosine mimetic 4 '-carboxymethyloxy-3 '-phosphonophenylalanine (Cpp): Exploitation in the design of nonpeptide inhibitors of pp60(Src) SH2 domain, BIOORG MED, 11(17), 2001, pp. 2319-2323
Selective inhibition of Src SH2 by a novel thiol-targeting tricarbonyl-modified inhibitor and mechanistic analysis by H-1/C-13 NMR spectroscopy
Authors: Sundaramoorthi, R Siedem, C Vu, CB Dalgarno, DC Laird, EC Botfield, MC Combs, AB Adams, SE Yuan, RW Weigele, M Narula, SS
Citation: R. Sundaramoorthi et al., Selective inhibition of Src SH2 by a novel thiol-targeting tricarbonyl-modified inhibitor and mechanistic analysis by H-1/C-13 NMR spectroscopy, BIOORG MED, 11(13), 2001, pp. 1665-1669
X-ray structure of citrate bound to Src SH2 leads to a high-affinity, bone-targeted Src SH2 inhibitor
Authors: Bohacek, RS Dalgarno, DC Hatada, M Jacobsen, VA Lynch, BA Macek, KJ Merry, T Metcalf, CA Narula, SS Sawyer, TK Shakespeare, WC Violette, SM Weigele, M
Citation: Rs. Bohacek et al., X-ray structure of citrate bound to Src SH2 leads to a high-affinity, bone-targeted Src SH2 inhibitor, J MED CHEM, 44(5), 2001, pp. 660-663
Structure-based design of novel bicyclic nonpeptide inhibitors for the SrcSH2 domain
Authors: Shakespeare, WC Bohacek, RS Azimioara, MD Macek, KJ Luke, GP Dalgarno, DC Hatada, MH Lu, XD Violette, SM Bartlett, C Sawyer, TK
Citation: Wc. Shakespeare et al., Structure-based design of novel bicyclic nonpeptide inhibitors for the SrcSH2 domain, J MED CHEM, 43(21), 2000, pp. 3815-3819
An efficient synthesis of a 4 '-phosphonodifluoromethyl-3 '-formyl-phenylalanine containing Src SH2 ligand
Authors: Shakespeare, WC Bohacek, RS Narula, SS Azimioara, MD Yuan, RW Dalgarno, DC Madden, L Botfield, MC Holt, DA
Citation: Wc. Shakespeare et al., An efficient synthesis of a 4 '-phosphonodifluoromethyl-3 '-formyl-phenylalanine containing Src SH2 ligand, BIOORG MED, 9(21), 1999, pp. 3109-3112
Structure-based design and synthesis of a novel class of Src SH2 inhibitors
Authors: Buchanan, JL Bohacek, RS Luke, GP Hatada, M Lu, XD Dalgarno, DC Narula, SS Yuan, R Holt, DA
Citation: Jl. Buchanan et al., Structure-based design and synthesis of a novel class of Src SH2 inhibitors, BIOORG MED, 9(16), 1999, pp. 2353-2358
Risultati: 1-7 |